{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:11:59Z","timestamp":1760235119381,"version":"build-2065373602"},"reference-count":33,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T00:00:00Z","timestamp":1627603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: A rare case of cor triatriatum sinistrum in combination with anomalies in the atrial septum and in the right atrium of a 60-year-old female body donor is described here. Materials and Methods: In addition to classical dissection, ultrasound and magnetic resonance imaging, computer tomography and cinematic rendering were performed. In a reference series of 59 regularly formed hearts (33 men, 26 women), we looked for features in the left and right atrium or atrial septum. In addition, we measured the atrial and ventricular wall thickness in 15 regularly formed hearts (7 men, 8 women). Results: In the case described, the left atrium was partly divided into two chambers by an intra-atrial membrane penetrated by two small openings. The 2.5 cm-high membrane originated in the upper level of the oval fossa and left an opening of about 4 cm in diameter. Apparently, the membrane did not lead to a functionally significant flow obstruction due to the broad intra-atrial communication between the proximal and distal chamber of the left atrium. In concordance with this fact, left atrial wall thickness was not elevated in the cor triatriatum sinistrum when compared with 15 regularly formed hearts. In addition, two further anomalies were found: 1. the oval fossa was deepened and arched in the direction of the left atrium; 2. the right atrium showed a membrane-like structure at its posterior and lateral walls, which began at the lower edge of the oval fossa. It probably corresponds to a strongly developed eustachian valve (valve of the inferior vena cava). Conclusions: The case described suggests that malformations in the development of the atrial septum and in the regression of the valve of the right sinus vein are involved in the pathogenesis of cor triatriatum sinistrum.<\/jats:p>","DOI":"10.3390\/medicina57080777","type":"journal-article","created":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T21:44:32Z","timestamp":1627854272000},"page":"777","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cor Triatriatum Sinistrum Combined with Changes in Atrial Septum and Right Atrium in a 60-Year-Old Woman"],"prefix":"10.3390","volume":"57","author":[{"given":"Horst","family":"Claassen","sequence":"first","affiliation":[{"name":"Department of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057 Rostock, Germany"},{"name":"Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Universit\u00e4tsstrasse 19, 91054 Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Busch","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Federal Armed Forces Hospital, Lesserstrasse 180, 22049 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2540-850X","authenticated-orcid":false,"given":"Matthias Stefan","family":"May","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Maximiliansplatz 3, 91054 Erlangen, Germany"},{"name":"Imaging Science Institute Erlangen, Ulmenweg 18, 91054 Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Schicht","sequence":"additional","affiliation":[{"name":"Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Universit\u00e4tsstrasse 19, 91054 Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Scholz","sequence":"additional","affiliation":[{"name":"Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Universit\u00e4tsstrasse 19, 91054 Erlangen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8189-811X","authenticated-orcid":false,"given":"Marko","family":"Schulze","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057 Rostock, Germany"},{"name":"AG 3 Anatomie und Zellbiologie, Medizinische Fakult\u00e4t OWL Universit\u00e4t Bielefeld, Morgenbreede 1, 33615 Bielefeld, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0527-0953","authenticated-orcid":false,"given":"Friedrich","family":"Paulsen","sequence":"additional","affiliation":[{"name":"Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Universit\u00e4tsstrasse 19, 91054 Erlangen, Germany"},{"name":"Department of Topographic Anatomy and Operative Surgery, Sechenov University, Rossolimo Street 15\/13, 119992 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Wree","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Rostock University Medical Center, Gertrudenstrasse 9, 18057 Rostock, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,7,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/674018","article-title":"Cor triatriatum sinister identified after new onset atrial fibrillation in an elderly man","volume":"2014","author":"Zepeda","year":"2014","journal-title":"Case. 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