{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T15:28:09Z","timestamp":1783524489731,"version":"3.55.0"},"reference-count":34,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T00:00:00Z","timestamp":1631664000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and objectives: To assess the pain relief of bipolar RFA combined or not with vertebroplasty in patients with painful vertebral metastases and to evaluate the feasibility and tolerance of the RFA procedure performed under local anesthesia. Materials and Methods: 25 patients (18 men, 7 women, mean age: 60.X y.o) with refractory painful vertebral metastasis were consecutively included between 2012 and 2019. A total of 29 radiofrequency ablation (RFA) procedures were performed under CT guidance, local anesthesia and nitrous oxide inhalation, including 16 procedures combined with vertebroplasty for bone consolidation purposes. Pain efficacy was clinically evaluated using the visual analogue scale (VAS) at day 1, 1 month, 3 months, 6 months and 12 months, and the tolerance of the procedure was evaluated. Results: Procedure tolerance was graded as either not painful or tolerable in 97% of cases. Follow-up postprocedure mean VAS score decrease was 74% at day 1: 6.6 (p &lt; 0.001), 79% at 1 month: 6.6 (p &lt; 0.001), 79% at 3 months: 6.5 (p &lt; 0.001), 77% at 6 months, and 79% at 12 months: 6.6 (p &lt; 0.001). Conclusions: Bipolar RFA, with or without combined vertebroplasty, appears to be an effective and reliable technique for the treatment of refractory vertebral metastases in patients in the palliative care setting. It is a feasible procedure under local anesthesia which is well tolerated by patients therefore allowing to broaden the indications of such procedures. Field of study: interventional radiology.<\/jats:p>","DOI":"10.3390\/medicina57090966","type":"journal-article","created":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T04:50:28Z","timestamp":1631681428000},"page":"966","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Bipolar Radiofrequency Ablation of Painful Spinal Bone Metastases Performed under Local Anesthesia: Feasibility Regarding Patient\u2019s Experience and Pain Outcome"],"prefix":"10.3390","volume":"57","author":[{"given":"Adrian","family":"Kastler","sequence":"first","affiliation":[{"name":"Diagnostic and Interventional Neuroradiology Unit, CHUGA Grenoble Hospital, Universit\u00e9 Grenoble Alpes, 38400 Saint Martin d\u2019Heres, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel-Ange","family":"Barb\u00e9","sequence":"additional","affiliation":[{"name":"Imagerie Medicale Pays D\u2019agde, 34300 Agde, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Alemann","sequence":"additional","affiliation":[{"name":"Cabinet M\u00e9dial Clemenceau Selestat, 67600 Selestat, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Hadjidekov","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital Lozenets, 1407 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1058-0884","authenticated-orcid":false,"given":"Francois H.","family":"Cornelis","sequence":"additional","affiliation":[{"name":"Adult Radiology Department, Necker Hospital, Paris V University, 75015 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Kastler","sequence":"additional","affiliation":[{"name":"Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3171\/2010.3.SPINE09202","article-title":"Diagnosis and management of metastatic spine disease. 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