{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:36:48Z","timestamp":1777905408640,"version":"3.51.4"},"reference-count":10,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2021,10,2]],"date-time":"2021-10-02T00:00:00Z","timestamp":1633132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background: Spontaneous hepatic rupture associated with the syndrome characterized by hemolysis, elevated liver enzymes, and a low platelet count (HELLP syndrome) is a rare and life-threatening condition, and only a few cases regarding the management of this condition through transcatheter arterial embolization (TAE) have been previously reported. Case summary: Herein, we report a case involving a 35-year-old pregnant woman who presented at 28 weeks of gestation with right upper quadrant pain, hypotension, and elevated levels of liver enzymes. Transabdominal ultrasound revealed fetal death. She required an emergency cesarean section, and hepatic rupture was identified after the fetus had been delivered. Hepatic packing and TAE were performed. The postprocedural course was uneventful, and the patient was discharged 14 days after she had been admitted to our hospital. Conclusions: Spontaneous hepatic rupture associated with HELLP syndrome is a very serious condition that requires prompt and decisive management. The high maternal and fetal mortality rates associated with this condition can be reduced through early accurate diagnosis and adequate management. The findings in the reported case indicate that TAE may be an attractive alternative to surgery for the management of spontaneous hepatic rupture associated with HELLP syndrome.<\/jats:p>","DOI":"10.3390\/medicina57101055","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:57:54Z","timestamp":1633917474000},"page":"1055","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Transcatheter Arterial Embolization for Spontaneous Hepatic Rupture Associated with HELLP Syndrome: A Case Report"],"prefix":"10.3390","volume":"57","author":[{"given":"In-Chul","family":"Nam","sequence":"first","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-Ho","family":"Won","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sungbin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyungsoo","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2267-0366","authenticated-orcid":false,"given":"Kyung-Nyeo","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Il","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7814-7430","authenticated-orcid":false,"given":"Eun","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji-Eun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Yool","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2832-8900","authenticated-orcid":false,"given":"Sung-Eun","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ajog.2006.01.016","article-title":"Characteristics and treatment of hepatic rupture caused by HELLP syndrome","volume":"195","author":"Araujo","year":"2006","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s00404-008-0829-7","article-title":"Postpartum spontaneous rupture of a liver hematoma associated with preeclampsia and HELLP syndrome","volume":"279","author":"Miguelote","year":"2009","journal-title":"Arch. Gynecol. Obstet."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/00006250-199102000-00001","article-title":"Spontaneous rupture of liver during pregnancy: Current therapy","volume":"77","author":"Smith","year":"1991","journal-title":"Obstet. Gynecol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ijgo.2012.03.042","article-title":"Pre-eclampsia\/eclampsia and hepatic rupture","volume":"118","year":"2012","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1097\/GRF.0000000000000253","article-title":"Diagnosis and management of HELLP syndrome complicated by liver hematoma","volume":"60","author":"Ditisheim","year":"2017","journal-title":"Clin. Obstet. Gynecol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jsurg.2009.04.001","article-title":"Diagnosis and surgical management of spontaneous hepatic rupture associated with HELLP syndrome","volume":"66","author":"Pavlis","year":"2009","journal-title":"J. Surg. Educ."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1148\/radiology.174.3.174-3-1039","article-title":"Spontaneous hepatic hemorrhage in preeclampsia: Treatment with hepatic arterial embolization","volume":"174","author":"Terasaki","year":"1990","journal-title":"Radiology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.tjog.2020.07.003","article-title":"Hepatic rupture in preeclampsia and HELLP syndrome: A catastrophic presentation","volume":"59","author":"Dubey","year":"2020","journal-title":"Taiwan J. Obstet. Gynecol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.ijscr.2017.07.057","article-title":"Right hepatectomy after spontaneous hepatic rupture in a patient with preeclampsia: A case report","volume":"39","author":"Millan","year":"2017","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3348\/kjr.2018.19.4.585","article-title":"Recent update of embolization of postpartum hemorrhage","volume":"19","author":"Chen","year":"2018","journal-title":"Korean J. Radiol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/57\/10\/1055\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:08:43Z","timestamp":1760166523000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/57\/10\/1055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,2]]},"references-count":10,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,10]]}},"alternative-id":["medicina57101055"],"URL":"https:\/\/doi.org\/10.3390\/medicina57101055","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,2]]}}}