{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T01:15:23Z","timestamp":1778202923315,"version":"3.51.4"},"reference-count":48,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T00:00:00Z","timestamp":1634515200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objective: During the COVID-19 pandemic, health systems worldwide made major changes to their organization, delaying diagnosis and treatment across a broad spectrum of pathologies. Concerning surgery, there was an evident reduction in all elective and emergency activities, particularly for benign pathologies such as acute diverticulitis, for which we have identified a reduction in emergency room presentation with mild forms and an increase with more severe forms. The aim of our review was to discover new data on emergency presentation for patients with acute diverticulitis during the Covid-19 pandemic and their current management, and to define a better methodology for surgical decision-making. Method: We conducted a scoping review on 25 trials, analyzing five points: reduced hospital access for patients with diverticulitis, the preferred treatment for non-complicated diverticulitis, the role of CT scanning in primary evaluation and percutaneous drainage as a treatment, and changes in surgical decision-making and preferred treatment strategies for complicated diverticulitis. Results: We found a decrease in emergency access for patients with diverticular disease, with an increased incidence of complicated diverticulitis. The preferred treatment was conservative for non-complicated forms and in patients with COVID-related pneumonia, percutaneous drainage for abscess, or with surgery delayed or reserved for diffuse peritonitis or sepsis. Conclusion: During the COVID-19 pandemic we observed an increased number of complicated forms of diverticulitis, while the total number decreased, possibly due to delay in hospital or ambulatory presentation because of the fear of contracting COVID-19. We observed a greater tendency to treat these more severe forms by conservative means or drainage. When surgery was necessary, there was a preference for an open approach or a delayed operation.<\/jats:p>","DOI":"10.3390\/medicina57101127","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T22:52:47Z","timestamp":1634683967000},"page":"1127","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Management of Acute Colonic Diverticulitis in the COVID-19 Era: A Scoping Review"],"prefix":"10.3390","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2457-0636","authenticated-orcid":false,"given":"Roberto","family":"Cirocchi","sequence":"first","affiliation":[{"name":"Department of Medicine and Surgery, University of Perugia, 06123 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Nascimbeni","sequence":"additional","affiliation":[{"name":"Department of Molecular and Translational Medicine, University of Brescia, 25121 Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0907-4965","authenticated-orcid":false,"given":"Gloria","family":"Burini","sequence":"additional","affiliation":[{"name":"General & Emergency Surgical Clinic, University of Ancona, Hospital \u201cOspedali Riuniti di Ancona\u201d, 60126 Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Boselli","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, University of Perugia, 06123 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Barberini","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, University of Perugia, 06123 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Davies","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Addenbrooke\u2019s Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salomone","family":"Di Saverio","sequence":"additional","affiliation":[{"name":"Colorectal Unit, Addenbrooke\u2019s Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0QQ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diletta","family":"Cassini","sequence":"additional","affiliation":[{"name":"General and Laparoscopic Surgery, ASST Nord Milano, Sesto San Giovanni, 20099 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4262-8467","authenticated-orcid":false,"given":"Bruno","family":"Amato","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples \u201cFederico II\u201d, 80138 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Andrea","family":"Binda","sequence":"additional","affiliation":[{"name":"General Surgery, Biomedical Institute, 16152 Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0237-1812","authenticated-orcid":false,"given":"Gabrio","family":"Bassotti","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, University of Perugia, 06123 Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical Features of Patients Infected With 2019 Novel Coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.21037\/atm-20-5272","article-title":"A Narrative Review on the Basic and Clinical Aspects of the Novel SARS-Cov-2, the Etiologic Agent of COVID-19","volume":"8","author":"Hokello","year":"2020","journal-title":"Ann. Transl. Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/joim.13184","article-title":"The Impact of Novel Coronavirus COVID-19 on Noncommunicable Disease Patients and Health Systems: A Review","volume":"289","author":"Chang","year":"2021","journal-title":"J. Intern. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s13017-020-00341-0","article-title":"WSES COVID-19 Emergency Surgery Survey Collaboration Group. Impact of the SARS-Cov-2 Pandemic on Emergency Surgery Services\u2014A Multi-National Survey among WSES Members","volume":"15","author":"Reichert","year":"2020","journal-title":"World J. Emerg. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1177\/2050640614547068","article-title":"Italian Consensus Conference for Colonic Diverticulosis and Diverticular Disease","volume":"2","author":"Cuomo","year":"2014","journal-title":"United Eur. Gastroenterol. J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.15403\/jgld-562","article-title":"International Consensus on Diverticulosis and Diverticular Disease. Statements from the 3rd International Symposium on Diverticular Disease","volume":"28","author":"Tursi","year":"2019","journal-title":"J. Gastrointest. Liver Dis."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/codi.15140","article-title":"European Society of Coloproctology: Guidelines for the Management of Diverticular Disease of the Colon","volume":"22","author":"Schultz","year":"2020","journal-title":"Color. Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"6757524","DOI":"10.1155\/2019\/6757524","article-title":"Gastrointestinal Tract Disorders in Older Age","volume":"2019","author":"Dumic","year":"2019","journal-title":"Can. J. Gastroenterol. Hepatol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s13304-020-00943-y","article-title":"Urgent and Emergency Surgery for Secondary Peritonitis During The COVID-19 Outbreak: An Unseen Burden of a Healthcare Crisis","volume":"73","author":"Fallani","year":"2021","journal-title":"Updat. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/XEB.0000000000000050","article-title":"Guidance for Conducting Systematic Scoping Reviews","volume":"13","author":"Peters","year":"2015","journal-title":"Int. J. Evid. Based Health."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1748-5908-5-69","article-title":"Scoping Studies: Advancing the Methodology","volume":"5","author":"Levac","year":"2010","journal-title":"Implement. Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/1364557032000119616","article-title":"Scoping Studies: Towards a Methodological Framework","volume":"8","author":"Arksey","year":"2005","journal-title":"Int. J. Soc. Res. Methodol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"467","DOI":"10.7326\/M18-0850","article-title":"PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation","volume":"169","author":"Tricco","year":"2018","journal-title":"Ann. Intern. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13017-020-00313-4","article-title":"2020 Update of the WSES Guidelines for the Management of Acute Colonic Diverticulitis in the Emergency Setting","volume":"15","author":"Sartelli","year":"2020","journal-title":"World J. Emerg. Surg."},{"key":"ref_15","unstructured":"OCEBM Levels of Evidence Working Group (2021, February 11). The Oxford Levels of Evidence 2. Available online: https:\/\/www.cebm.ox.ac.uk\/resources\/levels-of-evidence\/ocebm-levels-of-evidence."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1007\/s00268-020-05595-y","article-title":"Surgical Strategy During the COVID-19 Pandemic in a University Metropolitan Hospital in Milan, Italy","volume":"44","author":"Mariani","year":"2020","journal-title":"World J. Surg."},{"key":"ref_17","unstructured":"Intercollegiate General Surgery Guidance (2020, June 15). COVID-19 UPDATE. Available online: https:\/\/www.rcsed.ac.uk\/news-public-affairs\/news\/2020\/march\/intercollegiate-general-surgery-guidance-on-covid-19-update."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"468","DOI":"10.23736\/S0026-4733.20.08487-4","article-title":"COVID-19 and Acute Perforated Diverticulitis: Management and Surgical Timing","volume":"75","author":"Costanzi","year":"2020","journal-title":"Minerva Chir."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s11605-020-04798-x","article-title":"The Immediate, Hospital-Level Impact of Stay-at-Home Order on Diverticulitis Burden","volume":"25","author":"Soriano","year":"2021","journal-title":"J. Gastrointest. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1007\/s10140-020-01865-3","article-title":"Impact of the COVID-19 Pandemic on Emergency Department CT for Suspected Diverticulitis","volume":"27","author":"Gibson","year":"2020","journal-title":"Emerg. Radiol."},{"key":"ref_21","first-page":"11919","article-title":"Surgical Emergencies during SARS-Cov-2 Pandemic Lockdown: What Happened?","volume":"24","author":"Rosa","year":"2020","journal-title":"Eur. Rev. Med. Pharm. Sci."},{"key":"ref_22","first-page":"120","article-title":"Impact of COVID-19 on Emergency","volume":"8","author":"Hussain","year":"2020","journal-title":"Gen. Surg."},{"key":"ref_23","unstructured":"American College of Surgeons (ACS) (2020, June 13). COVID 19: Elective Case Triage Guidelines for Surgical Care. Available online: https:\/\/www.facs.org\/covid-19\/clinical-guidance\/elective-case."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1097\/TA.0000000000002727","article-title":"Laparoscopy at All Costs? Not Now During COVID-19 Outbreak and Not for Acute Care Surgery and Emergency Colorectal Surgery: A Practical Algorithm from a Hub Tertiary Teaching Hospital in Northern Lombardy, Italy","volume":"88","author":"Khan","year":"2020","journal-title":"J. Trauma Acute Care Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s10151-020-02209-6","article-title":"Italian Society of Colorectal Surgery Recommendations for Good Clinical Practice in Colorectal Surgery during the Novel Coronavirus Pandemic","volume":"24","author":"Gallo","year":"2020","journal-title":"Tech. Coloproctol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/ans.15900","article-title":"Impact of the COVID-19 Pandemic on Surgical Services: Early Experiences at a Nominated COVID-19 Centre","volume":"90","author":"McBride","year":"2020","journal-title":"ANZ J. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.ciresp.2020.04.031","article-title":"Atenci\u00f3n de la urgencia quir\u00fargica durante la pandemia COVID-19. Recomendaciones de la Asociaci\u00f3n Espa\u00f1ola de Cirujanos [Emergency surgery and trauma care during COVID-19 pandemic. Recommendations of the Spanish Association of Surgeons]","volume":"98","year":"2020","journal-title":"Cirug\u00eda Espa\u00f1ola"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"509","DOI":"10.11622\/smedj.2020070","article-title":"Deeply Reconsidering Elective Surgery: Worldwide Concerns Regarding Colorectal Surgery in a COVID-19 Pandemic and a Singapore Perspective","volume":"61","author":"Chew","year":"2020","journal-title":"Singap. Med. J."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/codi.15056","article-title":"Coronavirus Pandemic and Colorectal Surgery: Practical Advice Based on the Italian Experience","volume":"22","author":"Pata","year":"2020","journal-title":"Colorectal Dis."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1308\/rcsann.2020.0097","article-title":"Emergency Surgery During the COVID-19 Pandemic: What You Need to Know for Practice","volume":"102","author":"Chouillard","year":"2020","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"ref_31","unstructured":"Segura-Sampedro, J.J., Reyes, M.L., Garc\u00eda-Granero, A., and de la Portilla, F. (2020, June 15). Recomendaciones de Actuaci\u00f3n Patolog\u00eda Colorrectal de la AECP ante COVID-19. Available online: https:\/\/aecp-es.org\/images\/site\/slider\/Recomendaciones_de_actuacion_ante_COVID.pdf."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1002\/bjs.11627","article-title":"COVID-19 Pandemic: Perspectives on an Unfolding Crisis","volume":"107","author":"Spinelli","year":"2020","journal-title":"BJS"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.ciresp.2020.04.001","article-title":"SARS-CoV-2 Pandemic on the Activity and Professionals of a General Surgery and Digestive Surgery Service in a Tertiary Hospital","volume":"98","year":"2020","journal-title":"Cirug\u00eda Espa\u00f1ola"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/codi.15112","article-title":"COVID-19: Impact on Colorectal Surgery","volume":"22","author":"Wexner","year":"2020","journal-title":"Colorectal Dis."},{"key":"ref_35","first-page":"e20202614","article-title":"Management of Non Traumatic Surgical Emergencies during the COVID-19","volume":"47","author":"Parreira","year":"2020","journal-title":"Pandemia"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s10140-020-01854-6","article-title":"Patients Avoided Important Care During the Early Weeks of the Coronavirus Pandemic: Diverticulitis Patients were More Likely to Present with an Abscess on CT","volume":"28","author":"Zintsmaster","year":"2021","journal-title":"Emerg. Radiol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"S834","DOI":"10.14309\/01.ajg.0000708548.90106.60","article-title":"MSc2 S1625 Acute Perforated Diverticulitis as a Potential Complication of SARS-CoV-2 (COVID-19)","volume":"115","author":"Patel","year":"2020","journal-title":"Am. J. Gastroenterol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/ans.16562","article-title":"The Effect of National Public Health Interventions for COVID-19 on Emergency General Surgery in Northland, New Zealand","volume":"91","author":"McGuinness","year":"2021","journal-title":"ANZ J. Surg."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Hossain, N., Naidu, V., Hosny, S., Khalifa, M., Mathur, P., and Al Whouhayb, M. (2020). Hospital Presentations of Acute Diverticulitis During COVID-19 Pandemic may be More Likely to Require Surgery due to Increased Severity: A Single-Centre Experience. Am. Surg.","DOI":"10.1177\/0003134820982560"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2478\/jtim-2021-0019","article-title":"SARS-CoV-2 and Acute Diverticulitis: The Expanding Gastrointestinal Manifestations of COVID-19 Infection","volume":"9","author":"Weissman","year":"2021","journal-title":"J. Transl. Intern. Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1097\/DCR.0000000000001679","article-title":"Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis","volume":"63","author":"Hall","year":"2020","journal-title":"Dis. Colon Rectum"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10151-020-02346-y","article-title":"Management of Perforated Diverticulitis with Generalized Peritonitis. A Multidisciplinary Review and Position Paper","volume":"25","author":"Nascimbeni","year":"2021","journal-title":"Tech. Coloproctol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"102072","DOI":"10.1016\/j.jflm.2020.102072","article-title":"COVID-19 Pandemic: Coroner\u2019s Database of Death Inquiries with Clinical Epidemiology and Total and Excess Mortality Analyses in the District of Kildare March to June 2020","volume":"76","author":"Cusack","year":"2020","journal-title":"J. Forensic Leg. Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"106409","DOI":"10.1016\/j.ypmed.2020.106409","article-title":"Dying at Home of Covid-19: Meeting the Need for Home-Based Care","volume":"145","author":"Fallon","year":"2021","journal-title":"Prev. Med."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ijsu.2020.07.002","article-title":"Acute Care Surgery during the COVID-19 Pandemic in Spain: Changes in Volume, Causes and Complications. A Multicentre Retrospective Cohort Study","volume":"80","author":"Morales","year":"2020","journal-title":"Int. J. Surg."},{"key":"ref_46","unstructured":"COVIDSurg Collaborative (2020). Mortality and Pulmonary Complications in Patients Undergoing Surgery with Perioperative SARS-CoV-2 Infection: An International Cohort Study. Lancet, 396, 27\u201338."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e364","DOI":"10.1002\/bjs.11800","article-title":"Impact of Asymptomatic COVID-19 Patients in Global Surgical Practice During the COVID-19 Pandemic","volume":"107","author":"Bellato","year":"2020","journal-title":"BJS"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"020507","DOI":"10.7189\/jogh.10.020507","article-title":"Screening Policies, Preventive Measures and In-Hospital Infection of COVID-19 in Global Surgical Practices","volume":"10","author":"Bellato","year":"2020","journal-title":"J. Glob. Health"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/57\/10\/1127\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:17:02Z","timestamp":1760167022000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/57\/10\/1127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,18]]},"references-count":48,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,10]]}},"alternative-id":["medicina57101127"],"URL":"https:\/\/doi.org\/10.3390\/medicina57101127","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,18]]}}}