{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T17:05:03Z","timestamp":1778951103552,"version":"3.51.4"},"reference-count":65,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T00:00:00Z","timestamp":1635897600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Prematurity of birth occurs before the 37th week of gestation and affects up to 10% of births worldwide. It is correlated with critical outcomes; therefore, constant monitoring in neonatal intensive care units or home environments is required. The aim of this work was to develop solutions for remote neonatal intensive supervision systems, which should assist medical diagnosis of premature infants and raise alarm at cardiac abnormalities, such as bradycardia. Additionally, the COVID-19 pandemic has put a worldwide stress upon the medical staff and the management of healthcare units. Materials and Methods: A traditional medical diagnosing scheme was set up, implemented with the aid of powerful mathematical operators. The algorithm was tailored to the infants\u2019 personal ECG characteristics and was tested on real ECG data from the publicly available PhysioNet database \u201cPreterm Infant Cardio-Respiratory Signals Database\u201d. Different processing problems were solved: noise filtering, baseline drift removal, event detection and compression of medical data using the \u00e0 trous wavelet transform. Results: In all 10 available clinical cases, the bradycardia events annotated by the physicians were correctly detected using the RR intervals. Compressing the ECG signals for remote transmission, we obtained compression ratios (CR) varying from 1.72 to 7.42, with the median CR value around 3. Conclusions: We noticed that a significant amount of noise can be added to a signal while monitoring using standard clinical sensors. We tried to offer solutions for these technical problems. Recent studies have shown that persons infected with the COVID-19 disease are frequently reported to develop cardiovascular symptoms and cardiac arrhythmias. An automatic surveillance system (both for neonates and adults) has a practical medical application. The proposed algorithm is personalized, no fixed reference value being applied, and the algorithm follows the neonate\u2019s cardiac rhythm changes. The performance depends on the characteristics of the input ECG. The signal-to-noise ratio of the processed ECG was improved, with a value of up to 10 dB.<\/jats:p>","DOI":"10.3390\/medicina57111199","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T21:57:49Z","timestamp":1635976669000},"page":"1199","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Automated Medical Care: Bradycardia Detection and Cardiac Monitoring of Preterm Infants"],"prefix":"10.3390","volume":"57","author":[{"given":"Beatrice","family":"Arvinti","sequence":"first","affiliation":[{"name":"Fundamentals of Physics for Engineers Department, \u201cPolitehnica\u201d University Timisoara, Bd. Vasile P\u00e2rvan 2, 300223 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5863-6613","authenticated-orcid":false,"given":"Emil Radu","family":"Iacob","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, \u201cVictor Babes\u201d University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0510-7344","authenticated-orcid":false,"given":"Alexandru","family":"Isar","sequence":"additional","affiliation":[{"name":"Faculty of Electronics, Telecommunications and Information Technologies, \u201cPolitehnica\u201d University Timisoara, Bd. Vasile P\u00e2rvan 2, 300223 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Iacob","sequence":"additional","affiliation":[{"name":"Department of Neonatology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marius","family":"Costache","sequence":"additional","affiliation":[{"name":"Fundamentals of Physics for Engineers Department, \u201cPolitehnica\u201d University Timisoara, Bd. Vasile P\u00e2rvan 2, 300223 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Sbrollini, A., Mancinelli, M., Marcantoni, I., Morettini, M., and Burattini, L. (2019, January 26\u201328). Bradycardia Assessment in Preterm Infants. 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