{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:41:52Z","timestamp":1760136112244,"version":"build-2065373602"},"reference-count":9,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T00:00:00Z","timestamp":1642377600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Cerebral venous sinus thrombosis (CVST) is a rare venous thromboembolic disease that affects young adults in their thirties, with a female predilection. Head trauma accounts for only 1\u20133% of cases among possible etiologies. Here, we present a particular case of trauma-related CVST with delayed-onset symptoms and signs in a young boy. A 12-year-old boy presented to the emergency department with non-specific visual symptoms 11 days after head trauma. Apart from mild-grade disc swelling in the right eye and dyschromatopsia in both eyes, no significant findings were revealed during physical examinations and a non-contrast cranial computed tomography (CT) scan. Unfortunately, the patient suffered multiple seizure attacks the following day. Trauma-related CVST, complicated by delayed-onset increased intracranial pressure, and bilateral papilledema were finally diagnosed. Physicians need increased awareness of a possible CVST diagnosis if a patient with a history of head trauma shows persistent or worsening neurological symptoms despite negative results on serial non-contrast cranial CT scans.<\/jats:p>","DOI":"10.3390\/medicina58010140","type":"journal-article","created":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T20:46:03Z","timestamp":1642452363000},"page":"140","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Delayed Onset Bilateral Papilledema in a Young Boy\u2019s Eyes after Trauma"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-9527","authenticated-orcid":false,"given":"Ting-Yi","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke-Hung","family":"Chien","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1007\/s10072-017-3082-7","article-title":"Cerebral venous thrombosis: Continental disparities","volume":"38","author":"Maali","year":"2017","journal-title":"Neurol. Sci."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1111\/jth.14210","article-title":"Cerebral venous sinus thrombosis","volume":"16","author":"Capecchi","year":"2018","journal-title":"J. Thromb. Haemost."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1111\/head.12873","article-title":"Cerebral Sinus Thrombosis","volume":"56","author":"Agrawal","year":"2016","journal-title":"Headache"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1161\/01.STR.0000117571.76197.26","article-title":"Prognosis of cerebral vein and dural sinus thrombosis: Results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT)","volume":"35","author":"Ferro","year":"2004","journal-title":"Stroke"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.nec.2010.03.006","article-title":"Cerebral venous sinus (sinovenous) thrombosis in children","volume":"21","author":"Dlamini","year":"2010","journal-title":"Neurosurg. Clin. N. Am."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/cxo.12092","article-title":"Papilloedema associated with dural venous sinus thrombosis","volume":"97","author":"Slagle","year":"2014","journal-title":"Clin. Exp. Optom."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ajo.2019.12.022","article-title":"Presentation and Progression of Papilledema in Cerebral Venous Sinus Thrombosis","volume":"213","author":"Liu","year":"2020","journal-title":"Am. J. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1161\/01.STR.0000173401.76085.98","article-title":"A negative D-dimer assay does not rule out cerebral venous thrombosis: A series of seventy-three patients","volume":"36","author":"Crassard","year":"2005","journal-title":"Stroke"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0049-3848(75)90148-6","article-title":"Immunologic measurement of antithrombin III-heparin cofactor and alpha2 macroglobulin in disseminated intravascular coagulation and hepatic failure coagulopathy","volume":"6","author":"Damus","year":"1975","journal-title":"Thromb. Res."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/1\/140\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:02:53Z","timestamp":1760133773000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/1\/140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,17]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1]]}},"alternative-id":["medicina58010140"],"URL":"https:\/\/doi.org\/10.3390\/medicina58010140","relation":{},"ISSN":["1648-9144"],"issn-type":[{"type":"electronic","value":"1648-9144"}],"subject":[],"published":{"date-parts":[[2022,1,17]]}}}