{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:51:29Z","timestamp":1760151089053,"version":"build-2065373602"},"reference-count":31,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2022,2,19]],"date-time":"2022-02-19T00:00:00Z","timestamp":1645228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Carcinosarcomas are biphasic tumors comprising carcinoma and sarcoma components that occur in many tissues but are rarely found in the orbit. A 70-year-old male presented to the ophthalmic clinic with progressive proptosis, having decreased vision in the left eye for 8 months. On examination, severe exophthalmos and lagophthalmos with limited extraocular movement were noted. Orbital computed tomography scans revealed a large, well-defined, heterogeneously enhanced mass in the left retrobulbar orbital cavity. The tumor was completely resected, and the pathological examination revealed a carcinosarcoma. The prognosis was excellent without local recurrence at 48 months postoperatively. Thus, when considering treatment for effective management of such tumors, tumor resection followed by radiotherapy or chemotherapy is highly recommended.<\/jats:p>","DOI":"10.3390\/medicina58020317","type":"journal-article","created":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T08:22:19Z","timestamp":1645431739000},"page":"317","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful Resection of Retrobulbar Carcinosarcoma without Recurrence: A Case Report"],"prefix":"10.3390","volume":"58","author":[{"given":"Chun-Hao","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Taichung Armed Forces General Hospital, Taichung City 41168, Taiwan"},{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4745-4088","authenticated-orcid":false,"given":"Lung-Chi","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Wei","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"},{"name":"Department of Pathology, Tungs\u2019 Taichung Metroharbor Hospital No. 699, Section 8, Taiwan Boulevard, Wuqi District, Taichung City 43503, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke-Hung","family":"Chien","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/S1368-8375(00)00016-6","article-title":"Salivary gland carcinosarcoma: Immunohistochemical, molecular genetic and electron microscopic findings","volume":"36","author":"Riedel","year":"2000","journal-title":"Oral Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.ygyno.2015.03.041","article-title":"Uterine carcinosarcoma: A review of the literature","volume":"137","author":"Cantrell","year":"2015","journal-title":"Gynecol Oncol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1097\/IGC.0000000000000296","article-title":"Gynecologic Cancer InterGroup (GCIG) consensus review for uterine and ovarian carcinosarcoma","volume":"24","author":"Ledermann","year":"2014","journal-title":"Int. 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