{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T18:21:48Z","timestamp":1785867708821,"version":"3.56.0"},"reference-count":10,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>The non-Hodgkin\u2019s lymphomas are a diverse group of lymphoid neoplasms that collectively rank fifth in cancer incidence and mortality. Patients treated with mediastinal radiotherapy and\/or anthracycline-containing chemotherapy are known to have increased risks of coronary heart disease, valvular heart disease, and heart failure. This may be the result of cancer treatment cardiotoxicity or may be due to accelerated development of cardiovascular disease. We presented 41-year-old male who was admitted to the hospital because of congestive heart failure. He has a medical history of non-Hodgkin\u2019s lymphoma treated with anthracycline-based chemotherapy and mediastinal radiotherapy almost 20 years ago. Echocardiography showed significant aortic valve stenosis, thickened and fibrotic pericardium. Coronary angiography showed diffuse three-vessel coronary artery disease. The patient was referred for surgical treatment. Aortic valve replacement, coronary artery bypass grafting and pericardiectomy were successfully performed, symptoms of heart failure reduced.<\/jats:p>","DOI":"10.3390\/medicina58040489","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T21:41:30Z","timestamp":1648590090000},"page":"489","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cardiovascular Disorder after Cardiotoxic Non-Hodking\u2019s Lymphoma Treatment: A Case Report"],"prefix":"10.3390","volume":"58","author":[{"given":"Diana","family":"\u017daliaduonyt\u0117","sequence":"first","affiliation":[{"name":"Department of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eiveni\u0173 St. 2, 50161 Kaunas, Lithuania"},{"name":"Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus St. 9, 44307 Kaunas, Lithuania"},{"name":"Kaunas Region Society of Cardiology, 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Kleinauskien\u0117","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eiveni\u0173 St. 2, 50161 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gintar\u0117","family":"Muckien\u0117","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eiveni\u0173 St. 2, 50161 Kaunas, Lithuania"},{"name":"Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus St. 9, 44307 Kaunas, Lithuania"},{"name":"Kaunas Region Society of Cardiology, 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vytautas","family":"Zabiela","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eiveni\u0173 St. 2, 50161 Kaunas, Lithuania"},{"name":"Medical Academy, Lithuanian University of Health Sciences, Mickeviciaus St. 9, 44307 Kaunas, Lithuania"},{"name":"Kaunas Region Society of Cardiology, 50009 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1093\/eurheartj\/ehw211","article-title":"2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC)","volume":"37","author":"Zamorano","year":"2016","journal-title":"Eur. Heart J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.4103\/jfmpc.jfmpc_1037_19","article-title":"Non-hodgkin lymphomas: A review","volume":"9","author":"Singh","year":"2020","journal-title":"J. Family Med. Prim. Care."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3837","DOI":"10.1200\/JCO.2017.72.4211","article-title":"Preexisting cardiovascular risk and subsequent heart failure among Non-Hodgkin lymphoma survivors","volume":"34","author":"Salz","year":"2017","journal-title":"J. Clin. Oncol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/jcpt.12124","article-title":"Incidence and risk-factors of CHOP\/R-CHOP-related cardiotoxicity in patients with aggressive Non-Hodgkin\u2019s lymphoma","volume":"39","author":"Limat","year":"2014","journal-title":"J. Clin. Pharm. Ther."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"214","DOI":"10.2174\/157340311799960645","article-title":"Anthracycline Cardiotoxicity: Prevalence, Pathogenesis and Treatment","volume":"7","author":"Volkova","year":"2012","journal-title":"Curr. Cardiol. Rev."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1007\/s11906-010-0146-y","article-title":"Mechanisms of anthracycline cardiotoxicity and strategies to decrease cardiac damage","volume":"12","author":"Geisberg","year":"2010","journal-title":"Curr. Hypertens. Rep."},{"key":"ref_7","first-page":"93","article-title":"Radiotherapy and anthracyclines\u2014cardiovascular toxicity","volume":"19","author":"Mozdzanowska","year":"2015","journal-title":"Contemp. Oncol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s11883-017-0658-x","article-title":"Radiation-induced cardiovascular disease","volume":"19","author":"Raghunathan","year":"2017","journal-title":"Curr. Atheroscler. Rep."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/clc.22634","article-title":"Short and long term radiation induced cardiovascular disease in patients with cancer","volume":"40","author":"Nielsen","year":"2017","journal-title":"Clin. Cardiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1093\/jjco\/hyx068","article-title":"Cardio-oncology: A multidisciplinary approach for detection, prevention and management of cardiac dysfunction in cancer patients","volume":"1","author":"Tajiri","year":"2017","journal-title":"Jpn. J. Clin. Oncol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/4\/489\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:45:24Z","timestamp":1760136324000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/4\/489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,29]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,4]]}},"alternative-id":["medicina58040489"],"URL":"https:\/\/doi.org\/10.3390\/medicina58040489","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,29]]}}}