{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T02:17:52Z","timestamp":1762049872667,"version":"build-2065373602"},"reference-count":27,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Complete mesocolon excision and high vascular ligation have become a standard procedure in the treatment of colon cancer. The transverse colon has certain embryological and anatomical particularities which require special attention in case of oncological surgeries. Proximal transverse colon cancer (TCC) can metastasize to the lymph nodes in the gastrocolic ligament. The aim of this study is to assess the tumor involvement of these lymph nodes and to determine the applicability of gastrocolic ligament lymph nodes dissection as the standard approach for proximal transverse colon cancer. Materials and Methods: this study analyzes the cases of patients admitted to the Surgery Department, diagnosed with proximal transverse colon cancer, with tumor invasion \u2265 T2 and for which complete mesocolon excision with high vascular ligation and lymphadenectomy of the gastrocolic ligament (No. 204, 206, 214v) were performed. Results: A total of 43 cases operated during 2015\u20132020 were included in the study. The median total number of retrieved central lymph nodes was 23 (range, 12\u201338), that had tumor involvement in 22 cases (51.2%). Gastrocolic ligament tumor involvement was found in 5 cases (11.6%). The median operation time was 180 min, while the median blood loss was 115 mL (range 0\u2013210). The median time of hospitalization was 6 days (range, 5\u201311). Grade IIIA in the Clavien-Dindo classification was noticed in 3 patients, with no mortality. Upon Kaplan\u2013Meier analysis, tumors &gt; T3 (p &lt; 0.016) and lymph node ratio &lt; 0.05 (p &lt; 0.025) were statistically significant. Conclusions: lymph node dissection of the gastrocolic ligament in patients with advanced proximal transverse colon cancer may improve the oncological outcome in T3\/T4 tumors, and therefore standardization could be feasible<\/jats:p>","DOI":"10.3390\/medicina58050596","type":"journal-article","created":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T11:45:55Z","timestamp":1650973555000},"page":"596","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Extended Lymphadenectomy for Proximal Transverse Colon Cancer: Is There a Place for Standardization?"],"prefix":"10.3390","volume":"58","author":[{"given":"R\u0103zvan C\u0103t\u0103lin","family":"Popescu","sequence":"first","affiliation":[{"name":"Department of General Surgery, Emergency Hospital of Constan\u021ba, 900591 Constanta, Romania"},{"name":"Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7104-747X","authenticated-orcid":false,"given":"Florin","family":"Botea","sequence":"additional","affiliation":[{"name":"\u201cDan Setlacec\u201d Center of General Surgery and Liver Transplantation, Fundeni Clinical Institute, 022328 Bucharest, Romania"},{"name":"Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7268-3723","authenticated-orcid":false,"given":"Eugen","family":"Dumitru","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania"},{"name":"Department of Gastroenterology, Emergency Hospital of Constan\u021ba, 900591 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6195-4500","authenticated-orcid":false,"given":"Laura","family":"Mazilu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania"},{"name":"Department of Oncology, Emergency Hospital of Constan\u021ba, 900591 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lumini\u021ba Gen\u021biana","family":"Micu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania"},{"name":"Department of Pathology, Emergency Hospital of Constan\u021ba, 900591 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Tocia","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania"},{"name":"Department of Gastroenterology, Emergency Hospital of Constan\u021ba, 900591 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Dumitru","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania"},{"name":"Department of Gastroenterology, Emergency Hospital of Constan\u021ba, 900591 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4216-6570","authenticated-orcid":false,"given":"Adina","family":"Croitoru","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Titu Maiorescu University, 031593 Bucharest, Romania"},{"name":"Department of Medical Oncology, Fundeni Clinical Institute, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoleta","family":"Leopa","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Emergency Hospital of Constan\u021ba, 900591 Constanta, Romania"},{"name":"Faculty of Medicine and Pharmacy Constanta, Ovidius University, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3322\/caac.21395","article-title":"Colorectal cancer statistics, 2017","volume":"67","author":"Siegel","year":"2017","journal-title":"CA Cancer J. 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