{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:55:10Z","timestamp":1787028910351,"version":"build-2736575974"},"reference-count":22,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"IRCCS","award":["Current Research Funds 2022"],"award-info":[{"award-number":["Current Research Funds 2022"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Personality change is an important psychiatric complication following stroke linked to severe affective dysregulation and behavioral alterations. Methods: We investigated personality traits in 20 patients (age 45.37 \u00b1 13.41 years) with subacute stroke submitted to rehabilitation training within 1\u20133 months after a first-onset stroke. All patients underwent psychological evaluation by using the Personality Inventory for DSM-5 for adults (PID-5), a specific instrument that enables traits (dimensions and facets) to be assessed by providing a personality profile, and the Inventory of Interpersonal Problems 47 (IIP-47), a brief and valid self-report measure for screening personality disorders. Results: Personality change was identified by a positive correlation IIP-47 and PID-5 (r = 0.76; p = 0.03). Our patients, after a stroke, presented maladaptive personality traits associated with negative affect such as anxiety, emotional lability, and rigid perfectionism, and they reported interpersonal problems. These negative affective disorders correlated positively with cluster C personality disorders, including the avoidant, dependent, and obsessive compulsive personality disorders. Conclusion: Preliminary results show personality changes in stroke survivors. The evaluation of personality changes could be useful to improve the management of the patient\u2019s behavioral alterations in a familiar environment and permit the possibility of prevention of psychological distress of the patients and their respective caregivers.<\/jats:p>","DOI":"10.3390\/medicina58050683","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T13:56:12Z","timestamp":1653054972000},"page":"683","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Investigations of Personality Trait in Subacute Post-Stroke Patients: Some Preliminary Observations"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8027-6098","authenticated-orcid":false,"given":"Viviana","family":"Lo Buono","sequence":"first","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Noto","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0282-405X","authenticated-orcid":false,"given":"Lilla","family":"Bonanno","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Formica","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4862-3832","authenticated-orcid":false,"given":"Francesco","family":"Corallo","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Zuckerman, M. 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