{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:42:06Z","timestamp":1780051326601,"version":"3.53.1"},"reference-count":24,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Malignant neoplasms are common causes of acute pleuropericardial effusion. Pleuropericarditis denotes poor patient prognosis, is associated with shortened average survival time, and represents a surgical emergency. Materials and Methods: We analyzed the impact of two minimally invasive surgical approaches, the type of cancer, and other clinical variables on the mortality of 338 patients with pleuropericarditis admitted to an emergency hospital in Romania between 2009 and 2020. All patients underwent minimally invasive surgeries to prevent the recurrence of the disease and to increase their life expectancy. Log-rank tests were used to check for survival probability differences by surgical approach. We also applied univariate and multivariate Cox proportional hazard models to assess the effect of each covariate. Results: No significant differences were found in the 2-year overall survival rate between patients who underwent the two types of surgery. The multivariate Cox proportional regression model adjusted for relevant covariates showed that age, having lung cancer, and a diagnosis of pericarditis and right pleural effusion increased the mortality risk. The surgical approach was not associated with mortality in these patients. Conclusion: These findings open up avenues for future research to advance the understanding of survival among patients with pleuropericarditis.<\/jats:p>","DOI":"10.3390\/medicina58060718","type":"journal-article","created":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T01:40:45Z","timestamp":1653702045000},"page":"718","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis\u2014A 10 Year Retrospective Observational Study"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2274-5666","authenticated-orcid":false,"given":"Claudiu-Eduard","family":"Nistor","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Central Military Emergency University Hospital Bucharest, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 010825 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camelia Stanciu","family":"G\u0103van","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Central Military Emergency University Hospital Bucharest, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 010825 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0924-2343","authenticated-orcid":false,"given":"Alexandra-Andreea","family":"Ciritel","sequence":"additional","affiliation":[{"name":"Family and Fertility Department, ESRC Centre for Population Change, Building 58, Room 2001, Faculty of Social Sciences, University of Southampton, Southampton SO17 1TW, UK"},{"name":"FMR Global Health, 22 Rue Jean Mermoz, 75008 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra Floriana","family":"Nemes","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Louis \u0162urcanu Clinical Emergency Hospital for Children, 300011 Timi\u015foara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Ciuche","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Central Military Emergency University Hospital Bucharest, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 010825 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/eurheartj\/ehv318","article-title":"ESC Guidelines for the diagnosis and management of pericardial diseases; The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC) Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS)","volume":"36","author":"Adler","year":"2015","journal-title":"Eur. 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