{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T22:27:45Z","timestamp":1768516065957,"version":"3.49.0"},"reference-count":6,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>In the last decades, several new and modern techniques have been developed for the continuous monitoring of vitals for patients undergoing surgery under general anesthesia. These complex methods are meant to come as an adjunct to classical monitoring protocols used in general anesthesia to increase patient safety. The main objectives of multimodal monitoring are avoiding the over- or underdosing of anesthetic drugs, adapting the concentration for the substances in use, reducing post-anesthetic complications, and increasing patient comfort. Recent studies have shown a series of benefits with significant clinical impact such as a reduced incidence of nausea and vomiting, shorter reversal times, a reduction in opioid consumption, shorter hospital stays, and an increase in patient satisfaction.<\/jats:p>","DOI":"10.3390\/medicina58070956","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T23:10:22Z","timestamp":1658272222000},"page":"956","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["General Anesthesia as a Multimodal Individualized Clinical Concept"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1286-4431","authenticated-orcid":false,"given":"Alexandru Florin","family":"Rogobete","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Clinic of Anaesthesia and Intensive Care, Emergency County Hospital \u201cPius Brinzeu\u201d, 325100 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorel","family":"Sandesc","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Clinic of Anaesthesia and Intensive Care, Emergency County Hospital \u201cPius Brinzeu\u201d, 325100 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Cotae, A.-M., \u0162igli\u015f, M., Cobilinschi, C., B\u0103etu, A., Iacob, D., and Grin\u0163escu, I. (2021). The Impact of Monitoring Depth of Anesthesia and Nociception on Postoperative Cognitive Function in Adult Multiple Trauma Patients. Medicina, 57.","DOI":"10.3390\/medicina57050408"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Rogobete, A., Bedreag, O., Papurica, M., Popovici, S., Bratu, L., Rata, A., Barsac, C., Maghiar, A., Garofil, D., and Negrea, M. (2021). Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance during General Anesthesia\u2014A New Era in Patient Safety Standards and Healthcare Management. Medicina, 57.","DOI":"10.20944\/preprints202011.0657.v2"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"\u021aigli\u0219, M., Neagu, T., Niculae, A., Lasc\u0103r, I., and Grin\u021bescu, I. (2020). Incidence of Iron Deficiency and the Role of Intravenous Iron Use in Perioperative Periods. Medicina, 56.","DOI":"10.3390\/medicina56100528"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Balan, C., Bubenek-Turconi, S.-I., Tomescu, D., and Valeanu, L. (2021). Ultrasound-Guided Regional Anesthesia\u2013Current Strategies for Enhanced Recovery after Cardiac Surgery. Medicina, 57.","DOI":"10.3390\/medicina57040312"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Fiedler, M., Sch\u00e4tzle, E., Contzen, M., Gernoth, C., Wei\u00df, C., Walter, T., Viergutz, T., and Kalenka, A. (2020). Evaluation of Different Positive End-Expiratory Pressures Using Supreme\u2122 Airway Laryngeal Mask during Minor Surgical Procedures in Children. Medicina, 56.","DOI":"10.3390\/medicina56100551"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Secosan, I., Virga, D., Crainiceanu, Z., Bratu, L., and Bratu, T. (2020). Infodemia: Another Enemy for Romanian Frontline Healthcare Workers to Fight during the COVID-19 Outbreak. Medicina, 56.","DOI":"10.3390\/medicina56120679"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/7\/956\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:53:54Z","timestamp":1760140434000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/7\/956"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,19]]},"references-count":6,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7]]}},"alternative-id":["medicina58070956"],"URL":"https:\/\/doi.org\/10.3390\/medicina58070956","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,19]]}}}