{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:14:24Z","timestamp":1760238864988,"version":"build-2065373602"},"reference-count":36,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,20]],"date-time":"2022-07-20T00:00:00Z","timestamp":1658275200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: the comorbidity of personality disorders in patients who use psychoactive substances is common in psychiatric practice. The epidemiology of disharmonious personality traits in patients with ADHD and addictions in adulthood is still insufficiently researched. The study investigated the typology of personality traits in a group of adult patients consuming psychoactive substances, in whom symptoms of ADHD were identified. Materials and Methods: the study evaluates a group of 104 patients with chronic psychoactive substances abuse, in whom symptoms of ADHD were identified in early adulthood, in terms of comorbid personality traits. Results: statistically significant data have been obtained regarding the presence of clinical traits characteristic for cluster B personality disorders, the patients presenting lower levels of self-control, self-image instability, difficulties in the areas of social relationships and own identity integration. Conclusions: ADHD symptomatology precedes the clinical traits of personality disorders in patients with addictions, negatively influencing chronic evolution and quality of life.<\/jats:p>","DOI":"10.3390\/medicina58070962","type":"journal-article","created":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T03:34:40Z","timestamp":1658374480000},"page":"962","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Maladaptive Personality Traits in a Group of Patients with Substance Use Disorder and ADHD"],"prefix":"10.3390","volume":"58","author":[{"given":"Alexandra Mariana","family":"Buic\u0103","sequence":"first","affiliation":[{"name":"Child and Adolescent Psychiatry Department, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1885-2231","authenticated-orcid":false,"given":"Diana Monica","family":"Preda","sequence":"additional","affiliation":[{"name":"\u201cGrigore Alexandrescu\u201d Emergency Children Hospital, 10556 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2127-2641","authenticated-orcid":false,"given":"Lucia Emanuela","family":"Andrei","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry Department, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela","family":"Stancu","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry Department, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolae","family":"Gic\u0103","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology Department, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florina","family":"Rad","sequence":"additional","affiliation":[{"name":"Child and Adolescent Psychiatry Department, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,20]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"Persistent variations in neuronal DNA methylation following cocaine self-administration and protracted abstinence in mice","volume":"4","author":"Zhao","year":"2021","journal-title":"Neuroepigenetics"},{"key":"ref_2","first-page":"7","article-title":"Epigenetics of Drug Addiction","volume":"11","author":"Steward","year":"2021","journal-title":"Cold Spring Harb. 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