{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T07:37:55Z","timestamp":1763105875210,"version":"build-2065373602"},"reference-count":9,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:00:00Z","timestamp":1658707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background: The main etiology of acute pancreatitis includes biliary origin and alcohol, although various other causes include drugs (i.e., L-asparaginase) or malignant tumors. Since accurate identification of etiologies is crucial for determining therapeutic planning, the assessment of cause should be performed as early as possible. Case presentation: A 57-year-old Korean man was admitted for chemotherapy. The patient did not drink alcohol for religious reason. 26 days prior to admission, a 4 cm-sized testicular mass was observed in ultrasound and he received right radial orchiectomy. Extranodal natural killer\/T-cell lymphoma, nasal type, was diagnosed. After confirming no additional abnormal findings, chemotherapy (using the regimens Dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide) was begun. On Day 8 of chemotherapy, L-asparaginase was started and he complained of sudden onset epigastric pain after 2 days. Acute pancreatitis was diagnosed and, in order to determine if the acute pancreatitis occurred due to L-asparaginase or pancreas involvement of extranodal natural killer\/T-cell lymphoma, endoscopic ultrasonography guided fine needle biopsy was performed and observed diffusely infiltrated tumor cells. Therefore, he was given a final diagnosis of acute pancreatitis due to pancreas involvement of extranodal natural killer\/T-cell lymphoma, nasal type. Discussion: Acute pancreatitis caused by pancreas involvement of extranodal natural killer\/T-cell lymphoma, nasal type, is a very rare disease but can occur during chemotherapy. To identify the cause of acute pancreatitis, endoscopic ultrasonography guided fine needle biopsy can be considered.<\/jats:p>","DOI":"10.3390\/medicina58080991","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T21:20:59Z","timestamp":1658784059000},"page":"991","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pancreas Involvement of Extranodal Natural Killer\/T-Cell Lymphoma, Nasal Type, Presenting as Acute Pancreatitis: A Case Report"],"prefix":"10.3390","volume":"58","author":[{"given":"Dong Wook","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Jeong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9903-1282","authenticated-orcid":false,"given":"Chang Min","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1742-7843.2005.pto_274.x","article-title":"Pathophysiology and treatment of acute pancreatitis: New therapeutic targets\u2014A ray of hope?","volume":"97","author":"Felderbauer","year":"2005","journal-title":"Basic Clin. 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Lett."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Lee, K.H., Kim, E.Y., Cho, J., Kang, D., Bang, S., Kim, H.K., Kim, G.H., Choi, H.J., Han, J.H., and Jeon, S.W. (2017). Risk factors associated with adverse events during endoscopic ultrasound-guided tissue sampling. 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