{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:21:47Z","timestamp":1773055307993,"version":"3.50.1"},"reference-count":42,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T00:00:00Z","timestamp":1659398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Purpose: To evaluate the long-term outcomes of femtosecond laser-assisted in situ keratomileusis (Femto-LASIK) to correct residual astigmatism after deep anterior lamellar keratoplasty (DALK). Methods: This retrospective case series study included 10 eyes that underwent Femto-LASIK after a DALK. The refractive error, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, thinnest corneal thickness (TCT), and central corneal thickness (CCT) were registered. The postoperative follow-up ranged between 36 and 60 months. Results: All surgeries were uneventful, with no intra- or postoperative complications. The mean UDVA (Snellen scale) rose from 0.13 \u00b1 0.05 to 0.47 \u00b1 0.15 six months after Femto-LASIK (p &lt; 0.001). All cases experienced a significant improvement in UDVA. None of the eyes lost lines of CDVA, and seven eyes (70%) improved the CDVA compared to preoperative values. The refractive cylinder changed from a preoperative value of \u22123.88 \u00b1 1.00 D to \u22120.93 \u00b1 0.39 six months after Femto-LASIK (p &lt; 0.0001). In eight eyes (80%), the UDVA and refractive outcomes remained stable at postoperative follow-up visits. In contrast, one eye experienced a refractive regression over the follow-up. TCT and CCT were stable at the different postoperative follow-up visits. Conclusions: Our findings suggest that Femto-LASIK might safely and effectively corrects residual astigmatism after DALK. Despite these encouraging results, further long-term studies, including a larger number of cases, are required to confirm the safety of the procedure. The refractive stability in eyes with prior RK might be lower than for other DALK indications.<\/jats:p>","DOI":"10.3390\/medicina58081036","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T00:15:26Z","timestamp":1659485726000},"page":"1036","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Femto-LASIK after Deep Anterior Lamellar Keratoplasty to Correct Residual Astigmatism: A Long-Term Case Series Study"],"prefix":"10.3390","volume":"58","author":[{"given":"Bel\u00e9n","family":"Alfonso-Bartolozzi","sequence":"first","affiliation":[{"name":"Fern\u00e1ndez-Vega Ophthalmological Institute, 33012 Oviedo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Lisa","sequence":"additional","affiliation":[{"name":"Fern\u00e1ndez-Vega Ophthalmological Institute, 33012 Oviedo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Fern\u00e1ndez-Vega-Cueto","sequence":"additional","affiliation":[{"name":"Fern\u00e1ndez-Vega Ophthalmological Institute, 33012 Oviedo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3927-2858","authenticated-orcid":false,"given":"David","family":"Madrid-Costa","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Eye Research Group (CEER), Faculty of Optics and Optometry, Universidad Complutense de Madrid, 28037 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 F.","family":"Alfonso","sequence":"additional","affiliation":[{"name":"Fern\u00e1ndez-Vega Ophthalmological Institute, 33012 Oviedo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ophtha.2010.11.002","article-title":"Deep anterior lamellar keratoplasty as an alternative to penetrating keratoplasty: A report by the American academy of ophthalmology","volume":"118","author":"Reinhart","year":"2011","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1016\/j.ophtha.2004.02.010","article-title":"Comparison of deep lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus","volume":"111","author":"Watson","year":"2004","journal-title":"Ophthalmology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ajo.2006.10.043","article-title":"Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts","volume":"143","author":"Ardjomand","year":"2007","journal-title":"Am. 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