{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T21:56:52Z","timestamp":1784325412982,"version":"3.55.0"},"reference-count":66,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objective: Acute Achilles tendon rupture (AATR) is a common injury with a significant impact on daily living. Although various systematic reviews and meta-analyses have been written on the topic, no actual consensus exists on the best treatment. We aimed to collect the highest quality of evidence on the subject and to produce a document to which to refer, from the diagnosis to the final treatment. Material and Methods: Inclusion criteria were systematic reviews discussing Achilles tendon rupture, concerning either diagnostic criteria, classification, or treatment; English language; clearly stated inclusion and exclusion criteria for patients\u2019 selection. Results: Thirteen systematic reviews were included in the study. A strong consensus exists about the higher risk of re-rupture associated with non-operative treatment and a higher risk of complications associated with surgical repair. Conclusions: The combination of minimally invasive repair and accelerated functional rehabilitation seems to offer the best results in the treatment of Achilles tendon rupture.<\/jats:p>","DOI":"10.3390\/medicina58091195","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:19:01Z","timestamp":1662077941000},"page":"1195","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Acute Achilles Tendon Rupture: An Evidence-Based Approach from the Diagnosis to the Treatment"],"prefix":"10.3390","volume":"58","author":[{"given":"Francesco","family":"Amendola","sequence":"first","affiliation":[{"name":"Plastic and Reconstructive Surgery Department, I.R.C.C.S. Istituto Ortopedico Galeazzi, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3892-3559","authenticated-orcid":false,"given":"L\u00e9a","family":"Barbasse","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Department, AP-HP, H\u00f4pital Saint-Louis, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Carbonaro","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Department, I.R.C.C.S. Istituto Ortopedico Galeazzi, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Alessandri-Bonetti","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Department, I.R.C.C.S. Istituto Ortopedico Galeazzi, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4141-7112","authenticated-orcid":false,"given":"Giuseppe","family":"Cottone","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Department, I.R.C.C.S. Istituto Ortopedico Galeazzi, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Riccio","sequence":"additional","affiliation":[{"name":"Hand Surgery Unit, Department of Plastic and Reconstructive Surgery, Azienda \u201cOspedali Riuniti\u201d, Via Conca 21, 60126 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2977-7828","authenticated-orcid":false,"given":"Francesco","family":"De Francesco","sequence":"additional","affiliation":[{"name":"Hand Surgery Unit, Department of Plastic and Reconstructive Surgery, Azienda \u201cOspedali Riuniti\u201d, Via Conca 21, 60126 Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Vaienti","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery Department, I.R.C.C.S. Istituto Ortopedico Galeazzi, 20122 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Serror","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Department, AP-HP, H\u00f4pital Saint-Louis, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Ma, G.W., and Griffith, T.G. (1977). Percutaneous repair of acute closed ruptured Achilles tendon: A new technique. Clin. Orthop. Relat. Res., 247\u2013255.","DOI":"10.1097\/00003086-197710000-00036"},{"key":"ref_2","first-page":"224","article-title":"Percutaneous technique for Achilles tendon repair with the Dresden Instruments","volume":"108","author":"Amlang","year":"2005","journal-title":"Der Unf."},{"key":"ref_3","first-page":"345","article-title":"Treatment of subcutaneous ruptures of the Achilles tendon by percutaneous tenorraphy","volume":"78","author":"Delponte","year":"1992","journal-title":"Rev. Chir. Orthop. Reparatrice Appar. Mot."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"556","DOI":"10.2106\/00004623-200202000-00001","article-title":"Limited open repair of Achilles tendon ruptures: A technique with a new instrument and findings of a prospective multicenter study","volume":"84","author":"Assal","year":"2002","journal-title":"J. Bone Jt. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1007\/s40279-014-0200-z","article-title":"Predictors of primary Achilles tendon ruptures","volume":"44","author":"Claessen","year":"2014","journal-title":"Sports Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.jemermed.2021.09.008","article-title":"Diagnosing Achilles Tendon Rupture with Ultrasound in Patients Treated Surgically: A Systematic Review and Meta-Analysis","volume":"61","author":"Aminlari","year":"2021","journal-title":"J. Emerg. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2325967120909918","DOI":"10.1177\/2325967120909918","article-title":"Operative versus Nonoperative Treatment of Acute Achilles Tendon Ruptures: A Pilot Economic Decision Analysis","volume":"8","author":"Su","year":"2020","journal-title":"Orthop. J. Sports Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.fas.2020.07.004","article-title":"Multiple comparisons of the efficacy and safety for six treatments in Acute Achilles Tendon Rupture patients: A systematic review and network meta-analysis","volume":"27","author":"Shi","year":"2021","journal-title":"Foot Ankle Surg."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Attia, A.K., Mahmoud, K., d\u2019Hooghe, P., Bariteau, J., Labib, S.A., and Myerson, M.S. (2021). Outcomes and Complications of Open Versus Minimally Invasive Repair of Acute Achilles Tendon Ruptures: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Am. J. Sports Med., 3635465211053619.","DOI":"10.1177\/03635465211053619"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.2106\/JBJS.17.01364","article-title":"Minimally invasive versus open repair for acute Achilles tendon rupture meta-analysis showing reduced complications, with similar outcomes, after minimally invasive surgery","volume":"100","author":"Grassi","year":"2018","journal-title":"J. Bone Jt. Surg.-Am. Vol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1177\/0363546518824601","article-title":"Complications in the Management of Acute Achilles Tendon Rupture: A Systematic Review and Network Meta-analysis of 2060 Patients","volume":"47","author":"Wu","year":"2019","journal-title":"Am. J. Sports Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3728","DOI":"10.1177\/0363546521998284","article-title":"Treatment of Acute Achilles Tendon Ruptures: A Systematic Review and Meta-analysis of Complication Rates With Best- and Worst-Case Analyses for Rerupture Rates","volume":"49","author":"Seow","year":"2021","journal-title":"Am. J. Sports Med."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Khan, R.J., and Carey Smith, R.L. (2010). Surgical interventions for treating acute Achilles tendon ruptures. Cochrane Database Syst. Rev., CD003674.","DOI":"10.1002\/14651858.CD003674.pub4"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"k5120","DOI":"10.1136\/bmj.k5120","article-title":"Operative treatment versus nonoperative treatment of Achilles tendon ruptures: Systematic review and meta-analysis","volume":"364","author":"Ochen","year":"2019","journal-title":"BMJ"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"23259671211024605","DOI":"10.1177\/23259671211024605","article-title":"Is Early Controlled Motion and Weightbearing Recommended for Nonoperatively Treated Acute Achilles Tendon Rupture? A Systematic Review and Meta-Analysis","volume":"9","author":"Zhang","year":"2021","journal-title":"Orthop. J. Sports Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/j.injury.2022.01.028","article-title":"Early versus late weightbearing in conservative management of acute achilles tendon rupture: A systematic review and meta-analysis of randomized controlled trials","volume":"53","author":"Ghaddaf","year":"2022","journal-title":"Injury"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2325967119884071","DOI":"10.1177\/2325967119884071","article-title":"Defining Components of Early Functional Rehabilitation for Acute Achilles Tendon Rupture: A Systematic Review","volume":"7","author":"Zellers","year":"2019","journal-title":"Orthop. J. Sports Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"394","DOI":"10.2106\/00004623-198163030-00012","article-title":"Surgical and non-surgical treatment of Achilles tendon rupture. A prospective randomized study","volume":"63","author":"Nistor","year":"1981","journal-title":"J. Bone Jt. Surg.-Ser. A"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"899","DOI":"10.3928\/0147-7447-19920801-06","article-title":"Separation of tendon ends after Achilles tendon repair: A prospective, randomized, multicenter study","volume":"15","author":"Mortensen","year":"1992","journal-title":"Orthopedics"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1302\/0301-620X.74B2.1544953","article-title":"The Sheffield splint for controlled early mobilisation after rupture of the calcaneal tendon: A prospective, randomised comparison with plaster treatment","volume":"74","author":"Saleh","year":"1992","journal-title":"J. Bone Jt. Surg.-Ser. B"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1177\/036354659302100606","article-title":"Operative versus nonoperative treatment of Achilles tendon rupture A prospective randomized study and review of the literature","volume":"21","author":"Cetti","year":"1993","journal-title":"Am. J. Sports Med."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"983","DOI":"10.2106\/00004623-199907000-00011","article-title":"Early motion of the ankle after operative treatment of a rupture of the Achilles tendon: A prospective, randomized clinical and radiographic study","volume":"81","author":"Mortensen","year":"1999","journal-title":"J. Bone Jt. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Majewski, M., Rickert, M., and Steinbruck, K. (2000). Die frische Achillessehnenruptur-Eine prospektive Untersuchung zur Beurteilung verschiedener Therapiem\u00f6glichkeiten. Der Orthop\u00e4de, 7.","DOI":"10.1007\/PL00003753"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1177\/107110070102200705","article-title":"Percutaneous vs. Open Repair of the Ruptured Achilles Tendon-A Prospective Randomized Controlled Study","volume":"22","author":"Lim","year":"2001","journal-title":"Foot Ankle Int."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1302\/0301-620X.83B6.0830843","article-title":"Acute rupture of tendo Achillis: A prospective, randomised study of comparison between surgical and non-surgical treatment","volume":"83","author":"Granhed","year":"2001","journal-title":"J. Bone Jt. Surgery. Br. Vol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1007\/s004020100312","article-title":"Functional treatment after surgical repair of acute Achilles tendon rupture: Wrap vs. walking cast","volume":"122","author":"Kerkhoffs","year":"2002","journal-title":"Arch. Orthop. Trauma. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1097\/01.TA.0000047945.20863.A2","article-title":"Early functional treatment versus early immobilization in tension of the musculotendinous unit after achilles rupture repair: A prospective, randomized, clinical study","volume":"54","author":"Kangas","year":"2003","journal-title":"J. Trauma Acute Care Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/S0020-1383(02)00205-X","article-title":"Immediate full-weight-bearing mobilisation for repaired Achilles tendon ruptures: A pilot study","volume":"34","author":"Costa","year":"2003","journal-title":"Injury"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1302\/0301-620X.88B1.16549","article-title":"Randomised controlled trials of immediate weight-bearing mobilisation for rupture of the tendo Achillis","volume":"88","author":"Costa","year":"2006","journal-title":"J. Bone Jt. Surg.-Ser. B"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1177\/0363546507307503","article-title":"Early motion for Achilles tendon ruptures: Is surgery important? A randomized, prospective study","volume":"35","author":"Twaddle","year":"2007","journal-title":"Am. J. Sports Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1177\/0363546506293255","article-title":"Achilles tendon elongation after rupture repair: A randomized comparison of 2 postoperative regimens","volume":"35","author":"Kangas","year":"2007","journal-title":"Am. J. Sports Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s00167-007-0448-z","article-title":"Open versus percutaneous repair in the treatment of acute Achilles tendon rupture: A randomized prospective study","volume":"16","author":"Gigante","year":"2008","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1177\/0363546508319312","article-title":"Acute Achilles tendon rupture: Minimally invasive surgery versus nonoperative treatment with immediate full weightbearing\u2014A randomized controlled trial","volume":"36","author":"Metz","year":"2008","journal-title":"Am. J. Sports Med."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.2106\/JBJS.G.01242","article-title":"The influence of early weight-bearing compared with non-weight-bearing after surgical repair of the achilles tendon","volume":"90","author":"Suchak","year":"2008","journal-title":"J. Bone Jt. Surg."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3113\/FAI-2009-0391","article-title":"Open Versus Minimal Invasive Repair With Achillon Device","volume":"30","author":"Aktas","year":"2009","journal-title":"Foot Ankle. Int."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.2106\/JBJS.G.01089","article-title":"Augmented compared with nonaugmented surgical repair of a fresh total achilles tendon rupture: A prospective randomized study","volume":"91","author":"Pajala","year":"2009","journal-title":"J. Bone Jt. Surg."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1177\/0363546510376052","article-title":"Acute achilles tendon rupture: A randomized, controlled study comparing surgical and nonsurgical treatments using validated outcome measures","volume":"38","author":"Olsson","year":"2010","journal-title":"Am. J. Sports Med."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.2106\/JBJS.I.01401","article-title":"Operative versus nonoperative treatment of acute achilles tendon ruptures: A multicenter randomized trial using accelerated functional rehabilitation","volume":"92","author":"Willits","year":"2010","journal-title":"J. Bone Jt. Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1302\/0301-620X.93B8.25998","article-title":"Operative versus non-operative treatment of acute rupture of tendo Achillis: A prospective randomised evaluation of functional outcome","volume":"93","author":"Keating","year":"2011","journal-title":"J. Bone Jt. Surgery. Br. Vol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00264-012-1737-9","article-title":"Efficacy and complications of open and minimally invasive surgery in acute Achilles tendon rupture: A prospective randomised clinical study-Preliminary report","volume":"37","author":"Bohatyrewicz","year":"2013","journal-title":"Int. Orthop."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s00590-013-1350-7","article-title":"Percutaneous versus open repair of acute Achilles tendon ruptures","volume":"24","author":"Karabinas","year":"2014","journal-title":"Eur. J. Orthop. Surg. Traumatol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1177\/0363546513503282","article-title":"Stable surgical repair with accelerated rehabilitation versus nonsurgical treatment for acute achilles tendon ruptures: A randomized controlled study","volume":"41","author":"Olsson","year":"2013","journal-title":"Am. J. Sports Med."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1177\/0363546513501785","article-title":"Early controlled tension improves the material properties of healing human achilles tendons after ruptures: A randomized trial","volume":"41","author":"Schepull","year":"2013","journal-title":"Am. J. Sports Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.2106\/JBJS.M.01273","article-title":"Nonoperative dynamic treatment of acute achilles tendon rupture: The influence of early weight-bearing on clinical outcome: A blinded, randomized controlled trial","volume":"96","author":"Barfod","year":"2014","journal-title":"J. Bone Jt. Surg.-Am. Vol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1177\/1071100714536167","article-title":"Functional treatment or cast immobilization after minimally invasive repair of an acute achilles tendon rupture: Prospective, randomized trial","volume":"35","author":"Groetelaers","year":"2014","journal-title":"Foot Ankle. Int."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.2106\/JBJS.M.00248","article-title":"Weight-bearing in the nonoperative treatment of acute achilles tendon ruptures: A randomized controlled trial","volume":"96","author":"Young","year":"2014","journal-title":"J. Bone Jt. Surg."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s00776-015-0710-z","article-title":"Weight bearing the same day versus non-weight bearing for 4 weeks in Achilles tendon rupture","volume":"20","author":"Korkmaz","year":"2015","journal-title":"J. Orthop. Sci."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/ans.12910","article-title":"Randomized controlled trial of accelerated rehabilitation versus standard protocol following surgical repair of ruptured Achilles tendon","volume":"85","author":"Porter","year":"2015","journal-title":"ANZ J. Surg."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1302\/0301-620X.97B5.34581","article-title":"Intermittent pneumatic compression reduces the risk of deep vein thrombosis during postoperative lower limb immobilisation: A prospective randomised trial of acute ruptures of the Achilles tendon","volume":"97-B","author":"Labruto","year":"2015","journal-title":"Bone Jt. J."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1177\/0363546516651060","article-title":"A prospective randomized trial comparing surgical and nonsurgical treatments of acute achilles tendon ruptures","volume":"44","author":"Lantto","year":"2016","journal-title":"Am. J. Sports Med."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.foot.2015.10.003","article-title":"Prospective randomized clinical trial of aggressive rehabilitation after acute Achilles tendon ruptures repaired with Dresden technique","volume":"26","author":"Marambio","year":"2016","journal-title":"Foot"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2106\/JBJS.O.00496","article-title":"Augmented compared with nonaugmented surgical repair after total achilles rupture results of a prospective randomized trial with thirteen or more years of follow-up","volume":"98","author":"Heikkinen","year":"2016","journal-title":"J. Bone Jt. Surg.-Am. Vol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"9364170","DOI":"10.1155\/2016\/9364170","article-title":"A Prospective Study of Platelet-Rich Plasma as Biological Augmentation for Acute Achilles Tendon Rupture Repair","volume":"2016","author":"Zou","year":"2016","journal-title":"Biomed. Res. Int."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1007\/s00167-016-4270-3","article-title":"Functional weight-bearing mobilization after Achilles tendon rupture enhances early healing response: A single-blinded randomized controlled trial","volume":"25","author":"Valkering","year":"2017","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.injury.2017.10.046","article-title":"A novel minimally invasive surgery combined with early exercise therapy promoting tendon regeneration in the treatment of spontaneous Achilles tendon rupture","volume":"49","author":"Aisaiding","year":"2018","journal-title":"Injury"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1177\/1071100718757971","article-title":"Outcome of Percutaneous Fixation of Acute Achilles Tendon Ruptures","volume":"39","author":"Rozis","year":"2018","journal-title":"Foot Ankle. Int."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1177\/0363546518781826","article-title":"The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial","volume":"46","author":"Eliasson","year":"2018","journal-title":"Am. J. Sports Med."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.fas.2019.07.011","article-title":"Outcomes of open \u201ccrown\u201d type v. percutaneous Bunnell type repair of acute Achilles tendon ruptures. Randomized control study","volume":"26","author":"Klinga","year":"2020","journal-title":"Foot Ankle Surg."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1053\/j.jfas.2019.02.002","article-title":"Acute Achilles Tendon Ruptures: Efficacy of Conservative and Surgical (Percutaneous, Open) Treatment\u2014A Randomized, Controlled, Clinical Trial","volume":"58","author":"Manent","year":"2019","journal-title":"J. Foot Ankle Surg."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1007\/s00167-018-5058-4","article-title":"Early weight-bearing in nonoperative treatment of acute Achilles tendon rupture did not influence mid-term outcome: A blinded, randomised controlled trial","volume":"27","author":"Kastoft","year":"2019","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s00167-019-05767-x","article-title":"Early mobilization does not reduce the risk of deep venous thrombosis after Achilles tendon rupture: A randomized controlled trial","volume":"28","author":"Aufwerber","year":"2020","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1136\/bjsports-2019-100709","article-title":"Efficacy of early controlled motion of the ankle compared with immobilisation in non-operative treatment of patients with an acute Achilles tendon rupture: An assessor-blinded, randomised controlled trial","volume":"54","author":"Barfod","year":"2020","journal-title":"Br. J. Sports Med."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0140-6736(19)32942-3","article-title":"Plaster cast versus functional brace for non-surgical treatment of Achilles tendon rupture (UKSTAR): A multicentre randomised controlled trial and economic evaluation","volume":"395","author":"Costa","year":"2020","journal-title":"Lancet"},{"key":"ref_64","first-page":"9","article-title":"Calf muscle function after Achilles tendon rupture A prospective, randomised study comparing surgical and non-surgical treatment","volume":"12","author":"Lind","year":"2002","journal-title":"J. Med. Sci. Sports"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Vaienti, L., Cottone, G., Zaccaria, G., Rampino Cordaro, E., and Amendola, F. (2020). One-Step Approach for Infections After Achilles Tendon Open Repair: The Distally Based Peroneus Brevis Muscle Flap. Int. J. Low. Extrem. Wounds, 1534734620951540.","DOI":"10.1177\/1534734620951540"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1056\/NEJMoa2108447","article-title":"Nonoperative or Surgical Treatment of Acute Achilles\u2019 Tendon Rupture","volume":"386","author":"Myhrvold","year":"2022","journal-title":"N. Engl. J. 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