{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T02:36:08Z","timestamp":1792722968710,"version":"4.5.0"},"reference-count":31,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Tuberculous pleurisy is a common extrapulmonary TB that poses a health threat. However, diagnosis of TB pleurisy is challenging because of the low positivity rate of pleural effusion mycobacterial culture and difficulty in retrieval of optimal pleural tissue. This study aimed to investigate the efficacy of mycobacterial culture from pleural tissue, obtained by forceps biopsy through medical pleuroscopy, in the diagnosis of TB pleurisy. Materials and Methods: This study retrospectively enrolled 68 TB pleurisy patients. Among them, 46 patients received semi-rigid pleuroscopy from April 2016 to March 2021 in a tertiary hospital. We analyzed the mycobacterial culture from pleural tissue obtained by forceps biopsy. Results: The average age of the study participants was 62.8 years, and 64.7% of them were men. In the pleuroscopic group, the sensitivity of positive Mycobacterium tuberculosis (M. TB) cultures for sputum, pleural effusion, and pleural tissue were 35.7% (15\/42), 34.8% (16\/46), and 78.3% (18\/23), respectively. High sensitivities of M. TB culture from pleural tissue were up to 94.4% and 91.7% when pleural characteristic patterns showed adhesion lesions and both adhesion lesions and presence of micronodules, respectively. Conclusions: M. TB culture from pleural tissue should be considered a routine test when facing unknown pleural effusion during pleuroscopic examination.<\/jats:p>","DOI":"10.3390\/medicina58091280","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T01:35:10Z","timestamp":1663292110000},"page":"1280","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Clinical Experience of Mycobacterial Culture Yield of Pleural Tissue by Pleuroscopic Pleural Biopsy among Tuberculous Pleurisy Patients"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0466-7796","authenticated-orcid":false,"given":"Chung-Shu","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Thoracic Medicine, School of Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei 105406, Taiwan"},{"name":"Department of Pulmonary and Critical Care Medicine, New Taipei Municipal Tucheng Hospital, New Taipei City 236017, Taiwan"},{"name":"Department of Respiratory Therapy, New Taipei Municipal Tucheng Hospital, New Taipei City 236017, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1660-7715","authenticated-orcid":false,"given":"Li-Chung","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine, School of Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei 105406, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9573-969X","authenticated-orcid":false,"given":"Chih-Hao","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine, School of Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei 105406, Taiwan"},{"name":"Department of Pulmonary and Critical Care Medicine, New Taipei Municipal Tucheng Hospital, New Taipei City 236017, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-Tsai","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine, School of Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei 105406, Taiwan"},{"name":"Department of Pulmonary and Critical Care Medicine, New Taipei Municipal Tucheng Hospital, New Taipei City 236017, Taiwan"},{"name":"Department of Respiratory Therapy, New Taipei Municipal Tucheng Hospital, New Taipei City 236017, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3755-0287","authenticated-orcid":false,"given":"Shih-Hong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine, School of Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei 105406, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Liang","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine, School of Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei 110301, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anatomic Pathology, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan 333423, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0834-564X","authenticated-orcid":false,"given":"Shu-Min","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine, School of Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taipei 105406, Taiwan"},{"name":"Department of Respiratory Therapy, College of Medicine, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 333423, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,15]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2021). 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