{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:11:36Z","timestamp":1787235096658,"version":"build-2736575974"},"reference-count":8,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical Templates AG, Egg, Zurich, Switzerland"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: To describe preliminary results upon the application of the \u201cCube Navigation System\u201d (CNS) for computed tomography (CT)-guided splanchnic nerve radiofrequency neurolysis. Materials and Methods: CT-guided splanchnic nerve neurolysis was performed in five patients; in all cases, neurolysis was performed under CT guidance using the CNS. The mean patient age was 71.6 years (range 54\u201381 years; male\/female: 5\/0). Technical success, parameters of the neurolysis session and complications were evaluated. Technical success was defined as a needle position on the defined target. Session parameters included procedure time and number of scans. The CIRSE reporting system was used for complications\u2019 classification and grading. Results: Technical success was obtained in all cases; in 1\/5 patients, a slight correction in needle orientation was necessary. Mean procedure time was 12.4 min (range 8\u201319 min); an average of four CT scans was recorded in the five neurolysis sessions. There were no complications or material failures reported in the present study. Conclusions: Preliminary results of the present study show that computed tomography (CT)-guided splanchnic nerve radiofrequency neurolysis using the CNS is an accurate and time-efficient percutaneous procedure. More prospective and comparative studies with larger patient samples are necessary for verification of this system as well as for drawing broader conclusions.<\/jats:p>","DOI":"10.3390\/medicina58101359","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T22:53:19Z","timestamp":1664405599000},"page":"1359","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Navigation Guidance for Percutaneous Splanchnic Nerve Radiofrequency Neurolysis: Preliminary Results"],"prefix":"10.3390","volume":"58","author":[{"given":"Stavros","family":"Grigoriadis","sequence":"first","affiliation":[{"name":"2nd Department of Radiology, National and Kapodistrian University of Athens, \u201cAttikon\u201d University Hospital, 12462 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Filippiadis","sequence":"additional","affiliation":[{"name":"2nd Department of Radiology, National and Kapodistrian University of Athens, \u201cAttikon\u201d University Hospital, 12462 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Stamatopoulou","sequence":"additional","affiliation":[{"name":"2nd Department of Radiology, National and Kapodistrian University of Athens, \u201cAttikon\u201d University Hospital, 12462 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efthimia","family":"Alexopoulou","sequence":"additional","affiliation":[{"name":"2nd Department of Radiology, National and Kapodistrian University of Athens, \u201cAttikon\u201d University Hospital, 12462 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaos","family":"Kelekis","sequence":"additional","affiliation":[{"name":"2nd Department of Radiology, National and Kapodistrian University of Athens, \u201cAttikon\u201d University Hospital, 12462 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5429-6041","authenticated-orcid":false,"given":"Alexis","family":"Kelekis","sequence":"additional","affiliation":[{"name":"2nd Department of Radiology, National and Kapodistrian University of Athens, \u201cAttikon\u201d University Hospital, 12462 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Mahnken, A.H., and Ricke, J. (2009). CT-guided interventions\u2014Indications, technique, pitfalls. CT- and MR-Guided Interventions in Radiology, Springer.","DOI":"10.1007\/978-3-540-73085-9"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1055\/s-0035-1564705","article-title":"Navigational tools for interventional radiology and interventional oncology applications","volume":"32","author":"Chehab","year":"2015","journal-title":"Semin. Interv. Radiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00234-018-2107-0","article-title":"Evaluation of a novel, patient-mounted system for CT-guided needle navigation-an ex vivo study","volume":"61","author":"Mokry","year":"2019","journal-title":"Neuroradiology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1007\/s00270-017-1703-4","article-title":"Cirse Quality Assurance Document and Standards for Classification of Complications: The Cirse Classification System","volume":"40","author":"Filippiadis","year":"2017","journal-title":"CardioVascular Interv. Radiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1007\/s00270-012-0527-5","article-title":"CT-guided interventions using a free-hand, optical tracking system: Initial clinical experience","volume":"36","author":"Schubert","year":"2013","journal-title":"CardioVascular Interv. Radiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1055\/s-0042-103691","article-title":"Comparison of Two Electromagnetic Navigation Systems For CT-Guided Punctures: A Phantom Study","volume":"188","author":"Putzer","year":"2016","journal-title":"Rofo"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Durand, P., Moreau-Gaudry, A., Silvent, A.S., Frandon, J., Chipon, E., M\u00e9dici, M., and Bricault, I. (2017). Computer assisted electromagnetic navigation improves accuracy in computed tomography guided interventions: A prospective randomized clinical trial. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0173751"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1016\/j.ejrad.2015.07.004","article-title":"Radiation dose and quickness of needle CT interventions using a laser navigation system (LNS) compared with conventional method","volume":"84","author":"Schulz","year":"2015","journal-title":"Eur. J. Radiol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/10\/1359\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:40:56Z","timestamp":1760143256000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/10\/1359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,28]]},"references-count":8,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["medicina58101359"],"URL":"https:\/\/doi.org\/10.3390\/medicina58101359","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,28]]}}}