{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T23:44:18Z","timestamp":1781135058032,"version":"3.54.1"},"reference-count":50,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,10,16]],"date-time":"2022-10-16T00:00:00Z","timestamp":1665878400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Hyperparathyroidism (HPT) is a rare endocrine disease associated with the elevated metabolism of calcium, vitamin D, and phosphate by the hyperfunctioning of the parathyroid glands. Here, we report our experience of parathyroidectomy using intraoperative parathyroid hormone (IOPTH) monitoring in a single tertiary hospital. Materials and Methods: From October 2018 to January 2022, a total of 47 patients underwent parathyroidectomy for HPT. We classified the patients into two groups\u2014primary HPT (PHPT, n = 37) and renal HPT (RHPT, n = 10)\u2014and then reviewed the patients\u2019 data, including their general characteristics, laboratory results, and perioperative complications. Results: Thirty-five of the thirty-seven patients in the PHPT group underwent focused parathyroidectomy, while all ten patients in the RHPT group underwent subtotal parathyroidectomy. IOPTH monitoring based on the Milan criteria was used in all cases. Preoperative and 2-week, 6-month, and 12-month postoperative parathyroid hormone (PTH) levels were within the normal range in the PHPT group, whereas they were higher than normal in the RHPT group. Transient hypocalcemia occurred only in the RHPT group, with calcium levels returning to normal levels 12 months after surgery. Conclusions: Parathyroidectomy with IOPTH monitoring in our hospital showed favorable clinical outcomes. However, owing to the small number of patients due to the low frequency of parathyroid disease, long-term, prospective studies are needed in the future.<\/jats:p>","DOI":"10.3390\/medicina58101464","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T02:29:46Z","timestamp":1665973786000},"page":"1464","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Single-Center Experience of Parathyroidectomy Using Intraoperative Parathyroid Hormone Monitoring"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5804-4490","authenticated-orcid":false,"given":"Seong Hoon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Surgery, Inha University Hospital, College of Medicine, Incheon 22332, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si Yeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, Inha University Hospital, College of Medicine, Incheon 22332, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Ah","family":"Min","sequence":"additional","affiliation":[{"name":"Department of Surgery, Inha University Hospital, College of Medicine, Incheon 22332, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3389-7294","authenticated-orcid":false,"given":"Young Mi","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Inha University Hospital, College of Medicine, Incheon 22332, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2442-664X","authenticated-orcid":false,"given":"Yun Suk","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Inha University Hospital, College of Medicine, Incheon 22332, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9296-8443","authenticated-orcid":false,"given":"Jin Wook","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Inha University Hospital, College of Medicine, Incheon 22332, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0140-6736(09)60507-9","article-title":"Hyperparathyroidism","volume":"374","author":"Fraser","year":"2009","journal-title":"Lancet"},{"key":"ref_2","unstructured":"Randolph, G.W. 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