{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:09:44Z","timestamp":1792789784637,"version":"4.5.0"},"reference-count":29,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["JP19KK0244"],"award-info":[{"award-number":["JP19KK0244"]}]},{"name":"JSPS KAKENHI","award":["JP17H04134"],"award-info":[{"award-number":["JP17H04134"]}]},{"name":"JSPS KAKENHI","award":["JP19KK0244"],"award-info":[{"award-number":["JP19KK0244"]}]},{"name":"JSPS KAKENHI","award":["JP17H04134"],"award-info":[{"award-number":["JP17H04134"]}]},{"name":"National Research, Development and Innovation Fund","award":["JP19KK0244"],"award-info":[{"award-number":["JP19KK0244"]}]},{"name":"National Research, Development and Innovation Fund","award":["JP17H04134"],"award-info":[{"award-number":["JP17H04134"]}]},{"name":"Hungarian National Laboratory","award":["JP19KK0244"],"award-info":[{"award-number":["JP19KK0244"]}]},{"name":"Hungarian National Laboratory","award":["JP17H04134"],"award-info":[{"award-number":["JP17H04134"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Osteoporosis is a major risk of fractures, harming patients\u2019 quality of life. Dual-energy X-ray absorptiometry (DXA), which can detect osteoporosis early, is too expensive to be conducted on a regular basis. Therefore, we aimed to evaluate a screening method using chest radiographs developed in Japan applied to another population. Materials and Methods: Fifty-five patients who had a chest radiograph and DXA and applied within three months of each test were recruited from the patient database of Semmelweis University (Budapest, Hungary). Graphical analysis of the chest radiographs was conducted to identify the ratio of the cortical bone in the clavicle of each patient. Two researchers performed the analysis, and multiple regression was conducted to determine the bone mineral density of each patient provided by DXA. Results: The Pearson correlation between two examiners\u2019 determinations of the cortical bone ratio was 0.769 (p &lt; 0.001). The multiple regression model proved to be statistically significant in identifying osteoporosis, but the model adopted for the Hungarian population was different compared to the Japanese population. Conclusions: This simple, economic Japanese graphical analysis method for chest radiographs may be feasible in detecting osteoporosis. Further studies with a larger population of patients with greater variety of ethnicity would be of value in improving the accuracy of this model.<\/jats:p>","DOI":"10.3390\/medicina58121765","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T05:45:22Z","timestamp":1669787122000},"page":"1765","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Utilizing Graphical Analysis of Chest Radiographs for Primary Screening of Osteoporosis"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3288-423X","authenticated-orcid":false,"given":"Soichiro","family":"Saeki","sequence":"first","affiliation":[{"name":"Center Hospital of the National Center for Global Health and Medicine, Tokyo 162-8655, Japan"},{"name":"Department of Global and Innovative Medicine, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouichi","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, Faculty of Health Sciences, Morinomiya University of Medical Sciences, Osaka 559-8611, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Tomizawa","sequence":"additional","affiliation":[{"name":"Center for Twin Research, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan"},{"name":"School of Nursing, Graduate School of Nursing, Osaka Metropolitan University, Osaka 545-8585, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szilvia","family":"Meszaros","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Oncology, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"Horvath","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Oncology, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Zoldi","sequence":"additional","affiliation":[{"name":"Medical Imaging Centre, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helga","family":"Szabo","sequence":"additional","affiliation":[{"name":"Medical Imaging Centre, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5909-3780","authenticated-orcid":false,"given":"Adam Domonkos","family":"Tarnoki","sequence":"additional","affiliation":[{"name":"Center for Twin Research, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan"},{"name":"Medical Imaging Centre, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7001-7647","authenticated-orcid":false,"given":"David Laszlo","family":"Tarnoki","sequence":"additional","affiliation":[{"name":"Center for Twin Research, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan"},{"name":"Medical Imaging Centre, Semmelweis University, 1082 Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6851-0598","authenticated-orcid":false,"given":"Takayuki","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Medical Physics & Engineering, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chika","family":"Honda","sequence":"additional","affiliation":[{"name":"Center for Twin Research, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan"},{"name":"Department of Public Health Nursing, Shiga University of Medical Science, Otsu 520-2192, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/00003086-200003000-00016","article-title":"Osteoporosis","volume":"372","author":"Lane","year":"2000","journal-title":"Clin. 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