{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T20:26:14Z","timestamp":1760300774087,"version":"build-2065373602"},"reference-count":11,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>In monochorionic twins with no evidence of chronic twin-to-twin transfusion syndrome or twin anemia-polycythemia sequence, a sudden onset of fetal transfusion syndrome after the second trimester of pregnancy is defined as acute twin-to-twin transfusion syndrome. Labor pain, change in the fetal position, and birth order are known risk factors for this condition, and the hemoglobin level of the donor twin is usually reported to be &lt;12 g\/dL. We report a recent case of acute twin-to-twin transfusion syndrome without effective labor pain causing cervical changes, resulting in fetal bradycardia and neonatal death after birth; however, the anemia of the donor twin was not as severe as has been reported previously in twin-to-twin transfusion syndrome cases.<\/jats:p>","DOI":"10.3390\/medicina58121813","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T04:46:46Z","timestamp":1670561206000},"page":"1813","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Acute Twin-to-Twin Transfusion Syndrome Resulting in Fetal Bradycardia and Neonatal Death: A Case Report"],"prefix":"10.3390","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9770-1580","authenticated-orcid":false,"given":"Mi Ju","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea"},{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu 41404, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Mi","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea"},{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu 41404, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4399-7627","authenticated-orcid":false,"given":"Hyun-Hwa","family":"Cha","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea"},{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu 41404, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haemin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu 41404, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8369-417X","authenticated-orcid":false,"given":"Hyo-Shin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu 41404, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won Joon","family":"Seong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu 41944, Republic of Korea"},{"name":"Department of Obstetrics and Gynecology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu 41404, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ijgo.2006.11.002","article-title":"Twin chorionicity and the risk of adverse perinatal outcome","volume":"96","author":"Becker","year":"2007","journal-title":"Int. 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Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000304512","article-title":"Twin anemia-polycythemia sequence: Diagnostic criteria, classification, perinatal management and outcome","volume":"27","author":"Slaghekke","year":"2010","journal-title":"Fetal. Diagn. Ther."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.siny.2008.02.002","article-title":"Fetal and neonatal haematological complications in monochorionic twins","volume":"13","author":"Lopriore","year":"2008","journal-title":"Semin Fetal. Neonatal. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3109\/14767058.2011.637146","article-title":"Acute twin-twin transfusion syndrome in labor: Pathophysiology and associated factors","volume":"25","author":"Skupski","year":"2012","journal-title":"J. Matern. Fetal. Neonatal. 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Gynaecol."},{"key":"ref_10","first-page":"257","article-title":"Frequency, distribution, and theoretical mechanisms of hematologic and weight discordance in monochorionic twins","volume":"80","author":"Wenstrom","year":"1992","journal-title":"Obstet. Gynecol."},{"key":"ref_11","first-page":"184","article-title":"Acute intrapartum twin-twin transfusion. A case report","volume":"37","author":"Sherer","year":"1992","journal-title":"J. Reprod. Med."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/12\/1813\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:37:05Z","timestamp":1760146625000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/58\/12\/1813"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,9]]},"references-count":11,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["medicina58121813"],"URL":"https:\/\/doi.org\/10.3390\/medicina58121813","relation":{},"ISSN":["1648-9144"],"issn-type":[{"type":"electronic","value":"1648-9144"}],"subject":[],"published":{"date-parts":[[2022,12,9]]}}}