{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T07:31:19Z","timestamp":1788852679893,"version":"build-2803163510"},"reference-count":35,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T00:00:00Z","timestamp":1671062400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Benign osseous tumors of the spinal column comprise about 10% of all spinal tumors and are rare cause for surgery. However, these tumors pose various management challenges and conventional surgery may be associated with significant morbidity. Previous reports on minimally invasive resection of these lesions are rare. We report a series of patients managed by total resection of benign osseous spine tumors using MIS techniques. Surgical decisions and technical considerations are discussed. Materials and Methods: A retrospective evaluation of prospectively collected data of patients who underwent minimally invasive surgery for removal of benign osseous vertebral tumors. Demographic, clinical and radiographic features, operative details and final pathological reports were summarized. Primary outcomes were completeness of tumor resection and pain relief assessed by VAS for back and leg pain. Secondary outcome measures were recurrence of tumor on repeat post-operative MRI and postoperative unstable deformity on standing scoliosis X-rays. Results: This series included 32 cases of primary osseous spine tumors resected by minimally invasive techniques. There were 17 males and 15 females aged 5\u201368 years (mean 23.3). The follow-up period was 8\u201390 months (mean 32 months) and the preoperative symptoms duration was 9\u201396 months. Axial spinal pain was the presenting symptom in all the patients. Five patients also complained about radicular pain and four patients had antalgic scoliosis. The tumor involved the thoracic spine in 12 cases, the lumbar segment in 11, the cervical in 5 and the sacral area in 4 cases. Complete tumor removal was performed in all patients. No procedure-related complications were encountered. Histopathology showed osteoid osteoma in 24 patients, osteoblastoma in 5 patients, and fibrous dysplasia, fibroadenoma and eosinophilic granuloma in one case each. All patients experienced significant pain relief after surgery, and had stopped pain medications by 12 months postoperatively. No patient suffered from tumor recurrence or spinal deformity. Conclusions: Minimally invasive surgery is feasible for total removal of selected benign vertebral tumors and may have some advantages over conventional surgical techniques.<\/jats:p>","DOI":"10.3390\/medicina58121840","type":"journal-article","created":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T01:52:30Z","timestamp":1671069150000},"page":"1840","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Minimally Invasive Resection of Benign Osseous Tumors of the Spinal Column: 10 Years\u2019 Experience and Long-Term Outcomes of a Specialized Center"],"prefix":"10.3390","volume":"58","author":[{"given":"Khalil","family":"Salame","sequence":"first","affiliation":[{"name":"Spine Surgery Unit, Department of Neurosurgery, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Weitzman 6, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zvi","family":"Lidar","sequence":"additional","affiliation":[{"name":"Spine Surgery Unit, Department of Neurosurgery, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Weitzman 6, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morsi","family":"Khashan","sequence":"additional","affiliation":[{"name":"Spine Surgery Unit, Department of Neurosurgery, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Weitzman 6, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dror","family":"Ofir","sequence":"additional","affiliation":[{"name":"Spine Surgery Unit, Department of Neurosurgery, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Weitzman 6, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilad J.","family":"Regev","sequence":"additional","affiliation":[{"name":"Spine Surgery Unit, Department of Neurosurgery, Tel Aviv Sourasky Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Weitzman 6, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S124","DOI":"10.1093\/neuros\/nyw064","article-title":"Spine Oncology-Primary Spine Tumors","volume":"80","author":"Dea","year":"2017","journal-title":"Neurosurgery"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1007\/s00586-006-0188-7","article-title":"Primary bone tumors of the spine: A 42-year survey from the Leeds Regional Bone Tumour Registry","volume":"16","author":"Kelly","year":"2007","journal-title":"Eur. 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