{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T05:08:17Z","timestamp":1784610497860,"version":"3.55.0"},"reference-count":20,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T00:00:00Z","timestamp":1679616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Konkuk University Medical Center Research","award":["K220116"],"award-info":[{"award-number":["K220116"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: One of the most challenging tasks in a clinical setting is to differentiate between complex regional pain syndrome (CRPS) type II and traumatic neuropathic pain (NeP). CRPS is characterized by several dysautonomic manifestations, such as edema, hyper\/hypohidrosis, skin color change, and tachycardia. This study compared the outcomes of autonomic function screening tests in patients with CRPS type II and traumatic NeP for diagnostic differentiation. Materials and Methods: CRPS type II was diagnosed according to the Budapest research criteria, while NeP was diagnosed according to the updated grading system suggested by the International Association for the Study of Pain Special Interest Group on Neuropathic Pain in 2016. Twenty patients with CRPS type II and twenty-five with traumatic NeP were investigated. Results: Twelve patients with CRPS type II presented abnormal results for the quantitative sudomotor axon reflex test (QSART). Abnormal QSART results were more common in the CRPS type II group. Conclusions: Analysis of QSART combined with other ancillary tests can help in the differential diagnosis of CRPS type II and traumatic NeP if factors influencing abnormal QSART are sufficiently controlled.<\/jats:p>","DOI":"10.3390\/medicina59040646","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T08:43:03Z","timestamp":1679647383000},"page":"646","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["A Pilot Study of Autonomic Function Screening Tests for Differentiating Complex Regional Pain Syndrome Type II and Traumatic Neuropathic Pain"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2920-1418","authenticated-orcid":false,"given":"Dayoung","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology, Konkuk University College of Medicine, Konkuk University Medical Center, Seoul 05030, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Konkuk University College of Medicine, Konkuk University Medical Center, Seoul 05030, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Konkuk University College of Medicine, Konkuk University Medical Center, Seoul 05030, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0378-2947","authenticated-orcid":false,"given":"Jeeyoung","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Neurology, Konkuk University College of Medicine, Konkuk University Medical Center, Seoul 05030, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyomin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Neurology, Konkuk University College of Medicine, Konkuk University Medical Center, Seoul 05030, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1526-4637.2006.00169.x","article-title":"Proposed New Diagnostic Criteria for Complex Regional Pain Syndrome","volume":"8","author":"Harden","year":"2007","journal-title":"Pain Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.pain.2010.04.030","article-title":"Validation of Proposed Diagnostic Criteria (the \u201cBudapest Criteria\u201d) for Complex Regional Pain Syndrome","volume":"150","author":"Harden","year":"2010","journal-title":"Pain"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3233\/NRE-208001","article-title":"Complex Regional Pain Syndrome: An Updated Comprehensive Review","volume":"47","author":"Kessler","year":"2020","journal-title":"NeuroRehabilitation"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Arcidiacono, U.A., Armocida, D., Pesce, A., Maiotti, M., Proietti, L., D\u2019Andrea, G., Santoro, A., and Frati, A. 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