{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T17:29:58Z","timestamp":1774114198290,"version":"3.50.1"},"reference-count":13,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T00:00:00Z","timestamp":1681862400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Non-puerperal uterine inversion is an extremely rare and potentially dangerous condition. Cases are poorly described in the literature, and their actual incidence is unknown. A 34-year-old nulliparous female patient visited the emergency department following a loss of consciousness. She had experienced continuous vaginal bleeding over the preceding two months, with a two-day history of worsening symptoms. The patient showed signs of hypovolemic shock secondary to unceasing vaginal bleeding. Ultrasound and computed tomography revealed an inverted uterus and a large hematoma inside the patient\u2019s vaginal cavity. An emergency explorative laparoscopy was performed, which confirmed uterine inversion. Initially, Johnson\u2019s maneuver was attempted under laparoscopic visualization, but this failed to achieve uterine reduction. Following the unsuccessful performance of Huntington\u2019s maneuver, a re-trial of the manual reduction allowed the uterus to recover to its normal anatomy. The patient\u2019s vaginal bleeding was dramatically reduced after successful uterine reduction. The pathologic report conducted confirmed endometrioid adenocarcinoma. Laparoscopic visualization is a feasible and safe procedure for achieving uterine reduction in cases of non-puerperal uterine inversion with an unconfirmed pathology. Uterine malignancies should be considered in patients with non-puerperal uterine inversion.<\/jats:p>","DOI":"10.3390\/medicina59040793","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T03:25:11Z","timestamp":1681961111000},"page":"793","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Rare Case Report of Successful Laparoscopy-Guided Reduction of Non-Puerperal Uterine Inversion"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2541-8879","authenticated-orcid":false,"given":"Seongmin","family":"Kim","sequence":"first","affiliation":[{"name":"Gynecologic Cancer Center, CHA Ilsan Medical Center, CHA University College of Medicine, 1205 Jungang-ro, Ilsandong-gu, Goyang-si 10414, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5546-0763","authenticated-orcid":false,"given":"Sanghoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Korea University College of Medicine, 73 Inchon-ro, Seongbuk-gu, Seoul 02841, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Yun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Korea University College of Medicine, 73 Inchon-ro, Seongbuk-gu, Seoul 02841, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1097\/00006254-200011000-00022","article-title":"Uterine inversion and corpus malignancies: A historical review","volume":"55","author":"Gowri","year":"2000","journal-title":"Obstet. Gynecol. Surv."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1159\/000488089","article-title":"Non-puerperal uterine inversion: A systematic review","volume":"83","author":"Silva","year":"2018","journal-title":"Gynecol. Obstet. Investig."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1080\/01443610400025838","article-title":"Uterine inversion associated with endometrial carcinoma: A case report","volume":"25","author":"Kumar","year":"2005","journal-title":"J. Obstet. Gynaecol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.crad.2003.11.007","article-title":"MRI of non-puerperal uterine inversion due to endometrial carcinoma","volume":"59","author":"Moulding","year":"2004","journal-title":"Clin. Radiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.ygyno.2005.02.023","article-title":"Non-puerperal uterine inversion associated with endometrial carcinoma--a case report","volume":"97","author":"Oguri","year":"2005","journal-title":"Gynecol. Oncol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1701-2163(16)35305-1","article-title":"Complete uterine inversion in a patient with endometrial cancer","volume":"34","author":"Prefontaine","year":"2012","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1080\/01443610701844366","article-title":"Postmenopausal uterine inversion treated by subtotal hysterectomy","volume":"28","author":"Frederick","year":"2008","journal-title":"J. Obstet. Gynaecol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10147-005-0544-3","article-title":"Nonpuerperal inversion of the uterus associated with endometrial cancer: A case report","volume":"11","author":"Ueda","year":"2006","journal-title":"Int. J. Clin. Oncol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1016\/j.ajog.2011.01.024","article-title":"Management of nonpuerperal uterine inversion using a combined laparoscopic and vaginal approach","volume":"204","author":"Auber","year":"2011","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s10397-015-0899-z","article-title":"Total laparoscopic hysterectomy for non-puerperal uterine inversion: Anatomical and operative considerations","volume":"12","author":"Minas","year":"2015","journal-title":"Gynecol. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1159\/000366475","article-title":"Uterus preserving reposition of non-puerperal uterine inversion under laparoscope: A case report and literature review","volume":"79","author":"Zhang","year":"2015","journal-title":"Gynecol. Obstet. Investig."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.jmig.2018.12.014","article-title":"Laparoscopic Management of Nonpuerperal Uterine Inversion","volume":"26","author":"De","year":"2019","journal-title":"J. Minim. Invasive Gynecol."},{"key":"ref_13","first-page":"81","article-title":"A Rare Case of Nonpuerperal Uterine Inversion Managed by a Combined Laparoscopic and Vaginal Approach","volume":"11","author":"Younas","year":"2019","journal-title":"J. S. Asian Fed. Obstet. Gynaecol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/4\/793\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:19:17Z","timestamp":1760123957000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/4\/793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,19]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["medicina59040793"],"URL":"https:\/\/doi.org\/10.3390\/medicina59040793","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,19]]}}}