{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:03:37Z","timestamp":1767650617197,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Invasive forms of aspergillosis of the nervous system are relatively rare and are usually diagnosed in immunocompromised patients. We present the case of a young female patient, treated in the last two months with corticosteroids and antifungal drug for pulmonary aspergillosis, who developed progressive paraparesis. An intramedullary abscess at the C7\u2013D1 level was identified and the lesion was treated with a combination of surgery and antifungal therapy. Histopathologic findings of surgical specimens showed myelomalacia with Aspergillus hyphae and a peripheral rim of neutrophils. We consider that the use of multiple drugs and corticosteroids for our patient\u2019s initial community pneumonia could be the factor that transformed her into a mildly immunocompromised individual and permitted the Aspergillus spp. to disseminate through the blood and into the spinal cord. Moreover, we highlight the fact that more attention should be paid to living and working conditions of the patients, as a simple colonization of the lung with Aspergillus spp. could develop, in a short time, into an invasive disease with a high risk of mortality.<\/jats:p>","DOI":"10.3390\/medicina59040806","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T03:01:48Z","timestamp":1682046108000},"page":"806","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cervico-Dorsal Intramedullary Spinal Cord Abscess with Aspergillus fumigates following Pulmonary Infection in an Immunocompetent Patient"],"prefix":"10.3390","volume":"59","author":[{"given":"Vasile Deniss","family":"Mereuta","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, St. Spiridon\u201d Emergency Clinical County Hospital, 700111 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anca","family":"Sava","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"},{"name":"Department of Pathology, \u201cProf. Dr. N. Oblu\u201d Emergency Clinical Hospital, 700309 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristinel Ionel","family":"Stan","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucian","family":"Eva","sequence":"additional","affiliation":[{"name":"2nd Neurosurgical Clinic, \u201cProf. Dr. N. Oblu\u201d Emergency Clinical Hospital, 700309 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela Florenta","family":"Dumitrescu","sequence":"additional","affiliation":[{"name":"Department of Pathology, \u201cProf. Dr. N. Oblu\u201d Emergency Clinical Hospital, 700309 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolaie","family":"Dobrin","sequence":"additional","affiliation":[{"name":"2nd Neurosurgical Clinic, \u201cProf. Dr. N. Oblu\u201d Emergency Clinical Hospital, 700309 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelia","family":"Tudorache","sequence":"additional","affiliation":[{"name":"Department of Radiology, \u201cProf. Dr. N. Oblu\u201d Emergency Clinical Hospital, 700309 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Chiriac","sequence":"additional","affiliation":[{"name":"2nd Neurosurgical Clinic, \u201cProf. Dr. N. Oblu\u201d Emergency Clinical Hospital, 700309 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina Ruxandra","family":"Strambu","sequence":"additional","affiliation":[{"name":"\u201cMarius Nasta\u201d Institute of Pneumology, 050159 Bucharest, Romania"},{"name":"Department of Pneumology, \u201cCarol Davila\u201d, University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1485-0543","authenticated-orcid":false,"given":"Dragos Andrei","family":"Chiran","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Maria","family":"Dumitrescu","sequence":"additional","affiliation":[{"name":"Department of Morpho-Functional Sciences I, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.3389\/fmicb.2018.01303","article-title":"Diagnostic Aspects of Veterinary and Human Aspergillosis","volume":"9","author":"Elad","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1365-2133.1971.tb14119.x","article-title":"Skin manifestations of disseminated aspergillosis","volume":"85","author":"Findlay","year":"1971","journal-title":"Br. J. 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