{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:06:30Z","timestamp":1760148390361,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T00:00:00Z","timestamp":1682640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and objectives: Capillary hemangiomas are rare, benign vascular tumors that mainly affect the skin and soft tissue, with scarce appearance within the nasal cavities and paranasal sinuses. Materials and methods: We present a case report of capillary hemangioma of the sphenoid sinus and a review of the literature in the last ten years. Results: Clinical and endoscopic examination of the nose, radiologic assessment and particular histologic features contribute to the correct diagnosis of capillary hemangioma of the nose and paranasal sinuses. Conclusions: Transnasal endoscopic resection of capillary hemangioma located in the nose and paranasal sinuses is a valuable treatment method with good outcomes.<\/jats:p>","DOI":"10.3390\/medicina59050858","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T10:51:52Z","timestamp":1682679112000},"page":"858","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Management of Capillary Hemangioma of the Sphenoid Sinus"],"prefix":"10.3390","volume":"59","author":[{"given":"Irina-Gabriela","family":"Ionita","sequence":"first","affiliation":[{"name":"ENT Department, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8th Eroii Sanitari Boulevard, 050474 Bucharest, Romania"},{"name":"\u201cProf. Dr. D. Hociota\u201d Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viorel","family":"Zainea","sequence":"additional","affiliation":[{"name":"ENT Department, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8th Eroii Sanitari Boulevard, 050474 Bucharest, Romania"},{"name":"\u201cProf. Dr. D. Hociota\u201d Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"Voiosu","sequence":"additional","affiliation":[{"name":"ENT Department, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8th Eroii Sanitari Boulevard, 050474 Bucharest, Romania"},{"name":"\u201cProf. Dr. D. Hociota\u201d Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian Dragos","family":"Stefanescu","sequence":"additional","affiliation":[{"name":"ENT Department, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8th Eroii Sanitari Boulevard, 050474 Bucharest, Romania"},{"name":"\u201cProf. Dr. D. Hociota\u201d Institute of Phonoaudiology and Functional ENT Surgery, 21st Mihail Cioranu Street, 061344 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina Aura","family":"Panea","sequence":"additional","affiliation":[{"name":"ENT Department, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8th Eroii Sanitari Boulevard, 050474 Bucharest, Romania"},{"name":"Neurology Department, Elias Emergency University Hospital, 17th Marasti Boulevard, 011461 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian Vasile","family":"Dumitru","sequence":"additional","affiliation":[{"name":"ENT Department, Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 8th Eroii Sanitari Boulevard, 050474 Bucharest, Romania"},{"name":"Pathology Department, Emergency University Hospital, 169th Independence Street, 050098 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruxandra Oana","family":"Alius","sequence":"additional","affiliation":[{"name":"\u201cProf. Dr. D. 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Case Rep."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"S117","DOI":"10.4103\/0973-029X.141321","article-title":"Update on the classification of hemangioma","volume":"18","author":"George","year":"2014","journal-title":"J. Oral Maxillofac. Pathol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Vukadinovi\u0107, T., Labus, M., Spasi\u0107, S., \u0110ur\u0111evi\u0107, B.V., and Peri\u0107, A. (2021). Maxillary Sinus Lobular Capillary Hemangioma in a 15-Year-Old Boy. Ear Nose Throat J., 0145561321993597.","DOI":"10.1177\/0145561321993597"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1016\/j.joms.2016.12.044","article-title":"Sinonasal hemangioma: Diagnosis, treatment, and follow-up of 37 patients at a single center","volume":"75","author":"Kim","year":"2017","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1097\/SCS.0000000000003480","article-title":"The Possible Role of Endoscopy in Diagnosis of Benign Tumors of the Nasal Cavity","volume":"28","author":"Min","year":"2017","journal-title":"J. Craniofac. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"107866","DOI":"10.1016\/j.ijscr.2022.107866","article-title":"Nasal lobular capillary hemangioma: Report of a case managed by endoscopic excision and pre-operative angio-embolization","volume":"102","author":"Albesher","year":"2023","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.wneu.2020.09.032","article-title":"Intracranial Capillary Hemangiomas: A Peripartum Presentation and Review of the Literature","volume":"145","author":"Massman","year":"2021","journal-title":"World Neurosurg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"104913","DOI":"10.1016\/j.amsu.2022.104913","article-title":"Recurrent posterior fossa intracranial capillary hemangioma in a pregnant woman: A case report and review of literature","volume":"84","author":"Mehrizi","year":"2022","journal-title":"Ann. Med. Surgery."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1007\/s12070-015-0918-4","article-title":"The Nasal Hemangioma","volume":"71","author":"Tan","year":"2019","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"bcr2013008695","DOI":"10.1136\/bcr-2013-008695","article-title":"Capillary haemangioma of the ethmoid sinus","volume":"2013","author":"Lightbody","year":"2013","journal-title":"BMJ Case Rep."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s12105-016-0697-6","article-title":"Update on Select Benign Mesenchymal and Meningothelial Sinonasal Tract Lesions","volume":"10","author":"Thompson","year":"2016","journal-title":"Head Neck Pathol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3348\/kjr.2015.16.3.566","article-title":"Computed tomography and magnetic resonance imaging findings of nasal cavity hemangiomas according to histological type","volume":"16","author":"Kim","year":"2015","journal-title":"Korean J. Radiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e933075","DOI":"10.12659\/AJCR.933075","article-title":"Recurrent Epistaxis and Unilateral Intranasal Mass in A Teenager","volume":"22","author":"Bradshaw","year":"2021","journal-title":"Am. J. Case Rep."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"bcr2014207070","DOI":"10.1136\/bcr-2014-207070","article-title":"Benign sinonasal capillary haemangioma","volume":"2014","author":"Stubbs","year":"2014","journal-title":"BMJ Case Rep."},{"key":"ref_15","first-page":"334","article-title":"Severe epistaxis in pregnancy due to nasal pyogenic granuloma: A case report","volume":"15","year":"2020","journal-title":"J. Taibah Univ. Med. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.2214\/AJR.12.10517","article-title":"Current Classification and Terminology of Pediatric Vascular Anomalies","volume":"201","author":"Kollipara","year":"2013","journal-title":"Am. J. Roentgenol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.anl.2017.01.012","article-title":"Features of sinonasal hemangioma: A retrospective study of 31 cases","volume":"44","author":"Takaishi","year":"2017","journal-title":"Auris Nasus Larynx"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"40","DOI":"10.4103\/2156-7514.119134","article-title":"Nasal lobular capillary hemangioma","volume":"3","author":"Patil","year":"2013","journal-title":"J. Clin. Imaging Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1007\/s12070-015-0885-9","article-title":"Lobular Capillary Hemangioma of the Ethmoid Sinus: A Report of Two Cases","volume":"71","author":"Binesh","year":"2019","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.5152\/balkanmedj.2014.13178","article-title":"Lobular capillary hemangioma of the nasal cavity: A retrospective study of 15 cases in taiwan","volume":"31","author":"Chi","year":"2014","journal-title":"Balk. Med J."},{"key":"ref_21","first-page":"577","article-title":"Cystic lymphangioma of nasopharynx in a 54-year-old man\u2014Case report. A new histogenetic hypothesis","volume":"59","author":"Sajin","year":"2018","journal-title":"Rom. J. Morphol. Embryol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1097\/SCS.0000000000007250","article-title":"Clinical Difference Between Capillary and Cavernous Hemangiomas of Nasal Cavity","volume":"32","author":"Lim","year":"2021","journal-title":"J. Craniofacial Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13005-022-00336-z","article-title":"Risky anatomical variations of sphenoid sinus and surrounding structures in endoscopic sinus surgery","volume":"18","author":"Fadda","year":"2022","journal-title":"Head Face Med."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.bjorl.2015.09.002","article-title":"Maxillary sinus hemangioma: Usefulness of embolization according to classification","volume":"83","author":"Hasegawa","year":"2017","journal-title":"Braz. J. Otorhinolaryngol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1002\/lary.25355","article-title":"Lobular capillary hemangioma formation: An unusual complication of submucous resection with power instrumentation of the inferior turbinate","volume":"125","author":"Gregorio","year":"2015","journal-title":"Laryngoscope"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s12105-012-0409-9","article-title":"Sinonasal lobular capillary hemangioma: A clinicopathologic study of 34 cases characterizing potential for local recurrence","volume":"7","author":"Smith","year":"2013","journal-title":"Head Neck Pathol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s43163-022-00306-x","article-title":"Demographic and clinical criteria of intranasal lobular capillary hemangioma: As retrospective multicentric audit","volume":"38","author":"Bargas","year":"2022","journal-title":"Egypt. J. Otolaryngol."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Kunimoto, K., Yamamoto, Y., and Jinnin, M. (2022). ISSVA Classification of Vascular Anomalies and Molecular Biology. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23042358"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1148\/rg.2016150197","article-title":"2014 Revised Classification of Vascular Lesions from the International Society for the Study of Vascular Anomalies: Radiologic-Pathologic Update","volume":"36","author":"Merrow","year":"2016","journal-title":"Radiographics"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/5\/858\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:26:01Z","timestamp":1760124361000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/5\/858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,28]]},"references-count":29,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["medicina59050858"],"URL":"https:\/\/doi.org\/10.3390\/medicina59050858","relation":{},"ISSN":["1648-9144"],"issn-type":[{"type":"electronic","value":"1648-9144"}],"subject":[],"published":{"date-parts":[[2023,4,28]]}}}