{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:09:35Z","timestamp":1760148575921,"version":"build-2065373602"},"reference-count":13,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T00:00:00Z","timestamp":1684540800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>The present article explores the benefits of combining periodontally accelerated osteogenic orthodontics (PAOO) with Invisalign for optimal orthodontic treatment outcomes. PAOO is an interdisciplinary dental technique that minimizes complications and accelerates tooth movement while enhancing various orthodontic treatments. In conjunction with Invisalign, PAOO provides a discreet and comfortable solution for patients seeking to improve their smile. The study presents two challenging cases successfully treated using this combined approach, emphasizing the technique\u2019s potential to reduce treatment times and improve orthodontic outcomes. The interdisciplinary approach of PAOO ensures long-term success and stability by preserving periodontal structures and addressing potential bony defects. By incorporating bone grafting materials, PAOO helps prevent common concerns in traditional orthodontic treatments, such as bony defects and gingival recession. Furthermore, the combination with Invisalign offers a more aesthetically pleasing and comfortable treatment experience, allowing patients to maintain their self-esteem and confidence throughout the treatment. Despite the potential advantages, dental professionals must manage patient expectations and address potential complications to ensure the best possible results. Overall, the integration of PAOO and Invisalign demonstrates a viable alternative for patients who do not want to proceed with orthognathic surgery, enhancing patient satisfaction and overall treatment outcomes.<\/jats:p>","DOI":"10.3390\/medicina59050987","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T03:57:32Z","timestamp":1684727852000},"page":"987","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Harnessing the Power of PAOO and Invisalign: An Interdisciplinary Approach to Orthodontic Care"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8404-6940","authenticated-orcid":false,"given":"Kayvon","family":"Javid","sequence":"first","affiliation":[{"name":"Department of Oral Surgery, School of Dentistry, Fluminense Federal University, Niter\u00f3i 24020-140, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0201-3273","authenticated-orcid":false,"given":"Rafael Coutinho","family":"Mello-Machado","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry, Universidade Igua\u00e7u, Nova Igua\u00e7u, Rio de Janeiro 26260-045, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Montemezzi","sequence":"additional","affiliation":[{"name":"Department of Dentistry, San Raffaele Hospital, 20132 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"dos Santos Pereira","sequence":"additional","affiliation":[{"name":"Department of Oral & Maxillofacial Surgery, University of Grande Rio-UNIGRANRIO, Rio de Janeiro 25071-202, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0751-4894","authenticated-orcid":false,"given":"Adam","family":"Lowenstein","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Administration, Tufts University School of Dental Medicine, Boston, MA 02111, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5775-0222","authenticated-orcid":false,"given":"Carlos Fernando","family":"Mour\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Dental Research Administration, Tufts University School of Dental Medicine, Boston, MA 02111, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Gao, J., Nguyen, T., Oberoi, S., Oh, H., Kapila, S., Kao, R.T., and Lin, G.-H. (2021). The Significance of Utilizing A Corticotomy on Periodontal and Orthodontic Outcomes: A Systematic Review and Meta-Analysis. Biology, 10.","DOI":"10.3390\/biology10080803"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ortho.2019.03.006","article-title":"Does periodontally accelerated osteogenic orthodontics improve orthodontic treatment outcome? A systematic review and meta-analysis","volume":"17","author":"Kamal","year":"2019","journal-title":"Int. Orthod."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/cap.10045","article-title":"A Novel Approach in Periodontally Accelerated Osteogenic Orthodontics (PAOO): A Case Report","volume":"9","author":"Soltani","year":"2019","journal-title":"Clin. Adv. Periodontics"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.12998\/wjcc.v9.i6.1367","article-title":"Periodontally accelerated osteogenic orthodontics with platelet-rich fibrin in an adult patient with periodontal disease: A case report and review of literature","volume":"9","author":"Xu","year":"2021","journal-title":"World J. Clin. Cases"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e169","DOI":"10.11607\/prd.4545","article-title":"Periodontal Effect of Periodontally Accelerated Osteogenic Orthodontics in Skeletal Angle Class III: A Nonrandomized, Controlled Trial","volume":"40","author":"Xu","year":"2020","journal-title":"Int. J. Periodontics Restor. Dent."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Pinho, T., Rocha, D., Ribeiro, S., Monteiro, F., Pascoal, S., and Azevedo, R. (2022). Interceptive Treatment with Invisalign(\u00ae) First in Moderate and Severe Cases: A Case Series. Children, 9.","DOI":"10.3390\/children9081176"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.ajodo.2019.06.025","article-title":"Clinical follow-up of corticotomy-accelerated Invisalign orthodontic treatment with Dental Monitoring","volume":"158","author":"Hannequin","year":"2020","journal-title":"Am. J. Orthod. Dentofac. Orthop."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jclinepi.2017.04.026","article-title":"CARE Guidelines for Case Reports: Explanation and Elaboration Document","volume":"89","author":"Riley","year":"2017","journal-title":"J. Clin. Epidemiol."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Gheno, E., Alves, G.G., Ghiretti, R., Mello-Machado, R.C., Signore, A., Louren\u00e7o, E.S., Leite, P.E.C., Mour\u00e3o, C., Sohn, D.S., and Calasans-Maia, M.D. (2022). \u201cSticky Bone\u201d Preparation Device: A Pilot Study on the Release of Cytokines and Growth Factors. Materials, 15.","DOI":"10.3390\/ma15041474"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1590\/0100-69912015006013","article-title":"Obtention of injectable platelets rich-fibrin (i-PRF) and its polymerization with bone graft","volume":"42","author":"Valiense","year":"2015","journal-title":"Rev. Col\u00e9gio Bras. Cir."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.4103\/JPBS.JPBS_298_18","article-title":"Periodontal Accelerated Osteogenic Orthodontics Technique for Rapid Orthodontic Tooth Movement: A Systematic Review","volume":"11","author":"Vannala","year":"2019","journal-title":"J. Pharm. Bioallied Sci."},{"key":"ref_12","first-page":"e24985","article-title":"The Effectiveness of Periodontally Accelerated Osteogenic Orthodontics (PAOO) in Accelerating Tooth Movement and Supporting Alveolar Bone Thickness During Orthodontic Treatment: A Systematic Review","volume":"14","author":"Alsino","year":"2022","journal-title":"Cureus"},{"key":"ref_13","first-page":"979","article-title":"Effectiveness of modified periodontally accelerated osteogenic orthodontics in skeletal class II malocclusion treated by a camouflage approach","volume":"14","author":"Wang","year":"2022","journal-title":"Am. J. Transl. Res."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/5\/987\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:38:57Z","timestamp":1760125137000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/5\/987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,20]]},"references-count":13,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["medicina59050987"],"URL":"https:\/\/doi.org\/10.3390\/medicina59050987","relation":{},"ISSN":["1648-9144"],"issn-type":[{"type":"electronic","value":"1648-9144"}],"subject":[],"published":{"date-parts":[[2023,5,20]]}}}