{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:40:03Z","timestamp":1792428003007,"version":"4.5.0"},"reference-count":45,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Skin scaffolding can be done using allografts and autografts. As a biological allograft, the skin of Oreochromis niloticus (ON) has been used due to its high type I and III collagen content. Oreochromis mossambicus (OM) is also a member of the Oreochromis family, but not much is known regarding its collagen content. As such, this study aimed to assess and compare the collagen content of the two fish species. Materials and Methods: This is a crossover study comparing the skin collagen contents of the two fish. Young fish were chosen, as they tend to have higher collagen concentrations. The skin samples were sterilized in chlorhexidine and increasing glycerol solutions and analyzed histochemically with Sirius red picrate under polarized light microscopy. Results: 6 young ON and 4 OM specimens were used. Baseline type I collagen was higher for OM, but at maximum sterilization it was higher for ON, with no differences in between Type III collagen was higher for OM across all comparisons with the exception of the last stage of sterilization. Generally, collagen concentrations were higher in highly sterilized samples. Conclusions: OM skin harvested from young fish, with its greater collagen III content may be a better candidate for use as a biological skin scaffold in the treatment of burn wounds, compared to ON.<\/jats:p>","DOI":"10.3390\/medicina59061002","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T10:51:56Z","timestamp":1684839116000},"page":"1002","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of Type I and Type III Collagen Concentration between Oreochromis mossambicus and Oreochromis niloticus in Relation to Skin Scaffolding"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5553-2536","authenticated-orcid":false,"given":"Bogdan","family":"Ciornei","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery and Orthopedics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300002 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9261-5309","authenticated-orcid":false,"given":"Adrian","family":"Vaduva","sequence":"additional","affiliation":[{"name":"Department of Pathology, Methodological Research Center ANAPATMOL, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300002 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4295-7487","authenticated-orcid":false,"given":"Vlad Laurentiu","family":"David","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Orthopedics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300002 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Popescu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, \u201cLouis Turcanu\u201d Emergency Children\u2019s Hospital, 300011 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1046-7272","authenticated-orcid":false,"given":"Dan Dumitru","family":"Vulcanescu","sequence":"additional","affiliation":[{"name":"Multidisciplinary Research Center on Antimicrobial Resistance (Multi-Rez), \u201cVictor Babes\u201c University of Medicine and Pharmacy, 300002 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Orthopedics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300002 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia Roberta","family":"Avram","sequence":"additional","affiliation":[{"name":"Department of Residential Training and Post-University Courses, \u201cVasile Goldis\u201d Western University, 300002 Arad, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina Cornelia","family":"Pacurari","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Medlife Hyperclinic, 300551 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugen Sorin","family":"Boia","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Orthopedics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300002 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,23]]},"reference":[{"key":"ref_1","unstructured":"WHO (2021, January 03). 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