{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T20:27:42Z","timestamp":1774038462553,"version":"3.50.1"},"reference-count":22,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: There is a lack of data about the survival of patients after the implantation of sutureless relative to stented bioprostheses in middle-income settings. The objective of this study was to compare the survival of people with isolated severe aortic stenosis after the implantation of sutureless and stented bioprostheses in a tertiary referral center in Serbia. Materials and Methods: This retrospective cohort study included all people treated for isolated severe aortic stenosis with sutureless and stented bioprostheses from 1 January 2018 to 1 July 2021 at the Institute for Cardiovascular Diseases \u201cDedinje\u201d. Demographic, clinical, perioperative and postoperative data were extracted from the medical records. The follow-up lasted for a median of 2 years. Results: The study sample comprised a total of 238 people with a stented (conventional) bioprosthesis and 101 people with a sutureless bioprosthesis (Perceval). Over the follow-up, 13.9% of people who received the conventional and 10.9% of people who received the Perceval valve died (p = 0.400). No difference in the overall survival was observed (p = 0.797). The multivariate Cox proportional hazard model suggested that being older, having a higher preoperative EuroScore II, having a stroke over the follow-up period and having valve-related complications were independently associated with all-cause mortality over a median of 2 years after the bioprosthesis implantation. Conclusions: This research conducted in a middle-income country supports previous findings in high-income countries regarding the survival of people with sutureless and stented valves. Survival after bioprosthesis implantation should be monitored long-term to ensure optimum postoperative outcomes.<\/jats:p>","DOI":"10.3390\/medicina59061032","type":"journal-article","created":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T16:10:53Z","timestamp":1685203853000},"page":"1032","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience"],"prefix":"10.3390","volume":"59","author":[{"given":"Marko","family":"Kaitovic","sequence":"first","affiliation":[{"name":"Cardiac Surgery Department, Institute for Cardiovascular Diseases \u201cDedinje\u201d, 11040 Belgrade, Serbia"},{"name":"Department of Surgery, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slobodan","family":"Micovic","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, Institute for Cardiovascular Diseases \u201cDedinje\u201d, 11040 Belgrade, Serbia"},{"name":"Department of Surgery, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Nesic","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, Institute for Cardiovascular Diseases \u201cDedinje\u201d, 11040 Belgrade, Serbia"},{"name":"Department of Surgery, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatjana","family":"Raickovic","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, Institute for Cardiovascular Diseases \u201cDedinje\u201d, 11040 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jelena","family":"Dotlic","sequence":"additional","affiliation":[{"name":"Clinic for Obstetrics and Gynecology, Clinical Center of Serbia, 11000 Belgrade, Serbia"},{"name":"Department of Gynecology and Obstetrics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Stojanovic","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Department, Institute for Cardiovascular Diseases \u201cDedinje\u201d, 11040 Belgrade, Serbia"},{"name":"Department of Surgery, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatjana","family":"Gazibara","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1136\/heartjnl-2021-319025","article-title":"Cumulative burden of clinically significant aortic stenosis in community-dwelling older adults","volume":"107","author":"Owens","year":"2021","journal-title":"Heart"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.pcad.2014.02.006","article-title":"The global burden of aortic stenosis","volume":"56","author":"Thaden","year":"2014","journal-title":"Prog. 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