{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T16:05:12Z","timestamp":1792598712053,"version":"4.5.0"},"reference-count":27,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Aim and Objectives: We aimed to test the impact of age on long-term urinary continence (\u226512 months) in patients undergoing robotic-assisted radical prostatectomy. Methods and Materials: We relied on an institutional tertiary-care database to identify the patients who underwent robotic-assisted radical prostatectomy between January 2014 and January 2021. Patients were divided into three age groups: age group one (\u226460 years), age group two (61\u201369 years) and age group three (\u226570 years). Multivariable logistic regression models tested the differences between the age groups in the analyses addressing long-term urinary continence after robotic-assisted radical prostatectomy. Results: Of the 201 prostate cancer patients treated with robotic-assisted radical prostatectomy, 49 (24%) were assigned to age group one (\u226460 years), 93 (46%) to age group two (61\u201369 years) and 59 (29%) to age group three (\u226570 years). The three age groups differed according to long-term urinary continence: 90% vs. 84% vs. 69% for, respectively, age group one vs. two vs. three (p = 0.018). In the multivariable logistic regression, age group one (Odds Ratio (OR) 4.73, 95% CI 1.44\u201318.65, p = 0.015) and 2 (OR 2.94; 95% CI 1.23\u20137.29; p = 0.017) were independent predictors for urinary continence, compared to age group three. Conclusion: Younger age, especially \u226460 years, was associated with better urinary continence after robotic-assisted radical prostatectomy. This observation is important at the point of patient education and should be discussed in informed consent.<\/jats:p>","DOI":"10.3390\/medicina59061153","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T01:31:31Z","timestamp":1686879091000},"page":"1153","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Impact of Age on Long-Term Urinary Continence after Robotic-Assisted Radical Prostatectomy"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4829-0241","authenticated-orcid":false,"given":"Cristina","family":"Cano Garcia","sequence":"first","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"},{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montr\u00e9al Health Center, Montr\u00e9al, QC H2X 0A9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4338-0889","authenticated-orcid":false,"given":"Mike","family":"Wenzel","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Humke","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarissa","family":"Wittler","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julius","family":"Dislich","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reha-Baris","family":"Incesu","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montr\u00e9al Health Center, Montr\u00e9al, QC H2X 0A9, Canada"},{"name":"Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20251 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8495-6621","authenticated-orcid":false,"given":"Jens","family":"K\u00f6llermann","sequence":"additional","affiliation":[{"name":"Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Steuber","sequence":"additional","affiliation":[{"name":"Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20251 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Graefen","sequence":"additional","affiliation":[{"name":"Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20251 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7033-1380","authenticated-orcid":false,"given":"Derya","family":"Tilki","sequence":"additional","affiliation":[{"name":"Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20251 Hamburg, Germany"},{"name":"Department of Urology, University Hospital Hamburg-Eppendorf, 20246 Hamburg, Germany"},{"name":"Department of Urology, Koc University Hospital, 34010 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre I.","family":"Karakiewicz","sequence":"additional","affiliation":[{"name":"Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montr\u00e9al Health Center, Montr\u00e9al, QC H2X 0A9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Kluth","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Preisser","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix K. H.","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Mandel","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt","family":"Hoeh","sequence":"additional","affiliation":[{"name":"Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.euf.2017.08.001","article-title":"Short- and Long-term Functional Outcomes and Quality of Life after Radical Prostatectomy: Patient-reported Outcomes from a Tertiary High-volume Center","volume":"3","author":"Pompe","year":"2017","journal-title":"Eur. Urol. Focus"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1111\/bju.14760","article-title":"A comparative study of robot-assisted and open radical prostatectomy in 10 790 men treated by highly trained surgeons for both procedures","volume":"123","author":"Haese","year":"2019","journal-title":"BJU Int."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1056\/NEJMoa1606220","article-title":"10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer","volume":"375","author":"Hamdy","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1056\/NEJMoa1113162","article-title":"Radical Prostatectomy versus Observation for Localized Prostate Cancer","volume":"367","author":"Wilt","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"ref_6","first-page":"59.e7","article-title":"Feasibility and outcome of radical prostatectomy following inductive neoadjuvant therapy in patients with suspicion of rectal infiltration","volume":"40","author":"Hoeh","year":"2021","journal-title":"Urol. Oncol. Semin. Orig. Investig."},{"key":"ref_7","first-page":"830.e17","article-title":"Radical prostatectomy for localized prostate cancer: 20-year oncological outcomes from a German high-volume center","volume":"39","author":"Wenzel","year":"2021","journal-title":"Urol. Oncol. Semin. Orig. Investig."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/bju.13499","article-title":"Symptomatic and quality-of-life outcomes after treatment for clinically localised prostate cancer: A systematic review","volume":"118","author":"Whiting","year":"2016","journal-title":"BJU Int."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Borges, R.C., Tobias-Machado, M., Gabriotti, E.N., Figueiredo, F.W.D.S., Bezerra, C.A., and Glina, S. (2019). Post-radical prostatectomy urinary incontinence: Is there any discrepancy between medical reports and patients\u2019 perceptions?. BMC Urol., 19.","DOI":"10.1186\/s12894-019-0464-6"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1557988320957535","DOI":"10.1177\/1557988320957535","article-title":"Current Mental Distress Among Men with a History of Radical Prostatectomy and Related Adverse Correlates","volume":"14","author":"Ilie","year":"2020","journal-title":"Am. J. Men\u2019s Health"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s11701-007-0009-y","article-title":"Age-stratified outcomes after robotic-assisted laparoscopic radical prostatectomy","volume":"1","author":"Zorn","year":"2007","journal-title":"J. Robot. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ejso.2015.04.006","article-title":"Age Stratified Comparative Analysis of Perioperative, Functional and Oncologic Outcomes in Patients after Robot Assisted Radical Prostatectomy\u2014A Propensity Score Matched Study","volume":"41","author":"Kumar","year":"2015","journal-title":"Eur. J. Surg. Oncol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s00345-022-03945-0","article-title":"Age-stratified outcomes after radical prostatectomy in a randomized setting (LAP-01): Do younger patients have more to lose?","volume":"40","author":"Holze","year":"2022","journal-title":"World J. Urol."},{"key":"ref_14","first-page":"203.e11","article-title":"The effect of age on functional outcomes after radical prostatectomy","volume":"33","author":"Mandel","year":"2015","journal-title":"Urol. Oncol. Semin. Orig. Investig."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/bju.12407","article-title":"Functional and oncological outcomes of patients aged <50 years treated with radical prostatectomy for localised prostate cancer in a European population","volume":"114","author":"Becker","year":"2013","journal-title":"BJU Int."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1089\/end.2017.0512","article-title":"Outcome of Robotic Radical Prostatectomy in Men Over 74","volume":"32","author":"Ubrig","year":"2018","journal-title":"J. Endourol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2791","DOI":"10.1007\/s00345-020-03096-0","article-title":"Functional and perioperative outcomes in elderly men after robotic-assisted radical prostatectomy for prostate cancer","volume":"38","author":"Traboulsi","year":"2020","journal-title":"World J. Urol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1097\/JU.0000000000002391","article-title":"How Does Age Affect Urinary Continence following Robot-Assisted Radical Prostatectomy? A Prospective Multi-Institutional Study Using Independently Collected, Validated Questionnaires","volume":"207","author":"Gondoputro","year":"2022","journal-title":"J. Urol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1007\/s00345-020-03304-x","article-title":"Oncological and functional outcomes in patients over 70 years of age treated with robotic radical prostatectomy: A propensity-matched analysis","volume":"39","author":"Gurung","year":"2020","journal-title":"World J. Urol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.eururo.2011.02.040","article-title":"Full Functional-Length Urethral Sphincter Preservation During Radical Prostatectomy","volume":"60","author":"Schlomm","year":"2011","journal-title":"Eur. Urol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"825183","DOI":"10.3389\/fsurg.2021.825183","article-title":"Anatomical Fundamentals and Current Surgical Knowledge of Prostate Anatomy Related to Functional and Oncological Outcomes for Robotic-Assisted Radical Prostatectomy","volume":"8","author":"Hoeh","year":"2022","journal-title":"Front. Surg."},{"key":"ref_22","first-page":"177","article-title":"Full functional-length urethral sphincter- and neurovascular bundle preservation improves long-term continence rates after robotic-assisted radical prostatectomy","volume":"17","author":"Hoeh","year":"2022","journal-title":"J. Robot. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"4738","DOI":"10.3390\/curroncol28060399","article-title":"Correlation of Urine Loss after Catheter Removal and Early Continence in Men Undergoing Radical Prostatectomy","volume":"28","author":"Hoeh","year":"2021","journal-title":"Curr. Oncol."},{"key":"ref_24","unstructured":"R Core Team (2020). R: A Language and Environment for Statistical Computing, R Foundation for Statistical Computing. Available online: https:\/\/www.R-project.org\/."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1111\/j.1464-410X.2009.08718.x","article-title":"Robot-assisted radical prostatectomy in men aged \u2265 70 years","volume":"104","author":"Greco","year":"2009","journal-title":"BJU Int."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.2147\/CMAR.S358054","article-title":"Quality of Life of Prostate Cancer Patients Undergoing Prostatectomy and Affective Temperament","volume":"14","author":"Brzoszczyk","year":"2022","journal-title":"Cancer Manag. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1634\/theoncologist.2009-0059","article-title":"The Chronology of Distress, Anxiety, and Depression in Older Prostate Cancer Patients","volume":"14","author":"Nelson","year":"2009","journal-title":"Oncologist"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/6\/1153\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:55:38Z","timestamp":1760126138000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/6\/1153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,15]]},"references-count":27,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["medicina59061153"],"URL":"https:\/\/doi.org\/10.3390\/medicina59061153","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,15]]}}}