{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:12:07Z","timestamp":1791216727186,"version":"4.1.0"},"reference-count":31,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T00:00:00Z","timestamp":1691020800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>(1) Background: Aggressive angiomyxoma is a mesenchymal cancer that is rare during pregnancy. It is a neoplasm that relapses and infiltrates the nearest structures. Our aim is to evaluate the management and outcomes of an observed case, in light of the current literature. (2) Methods: We observed this condition at the \u201cMaggiore della Carit\u00e0\u201d Hospital in Novara (Italy) in a patient with an initial twin pregnancy and a suspected pelvic mass. The words \u201cangiomyxoma\u201d and \u201cpregnancy\u201d were searched on the main online scientific search sources (PubMed, Google Scholar, Scopus, WES, and Embase, etc.). (3) Results: The patient underwent surgery with a complicated follow-up, but recent negative controls. We analyzed the literature about the topic and found only 24 similar clinical cases. (4) Conclusions: Considering the current literature, it is useful to assess an aggressive angiomyxoma in the differential diagnosis of soft masses in pregnant women. The treatment of choice is surgical excision, and vaginal delivery is feasible. The therapeutic decision depends on each case.<\/jats:p>","DOI":"10.3390\/medicina59081417","type":"journal-article","created":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T11:08:43Z","timestamp":1691060923000},"page":"1417","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4797-6161","authenticated-orcid":false,"given":"Carmen Imma","family":"Aquino","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, \u201cMaggiore della Carit\u00e0\u201d Hospital, University of Piemonte Orientale, 28100 Novara, Italy"},{"name":"Department of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5597-3035","authenticated-orcid":false,"given":"Raffaele","family":"Tinelli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u201cValle D\u2019Itria\u201d Hospital, Martina Franca, 74015 Taranto, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8478-5471","authenticated-orcid":false,"given":"Alessandro","family":"Libretti","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, \u201cMaggiore della Carit\u00e0\u201d Hospital, University of Piemonte Orientale, 28100 Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1106-6626","authenticated-orcid":false,"given":"Riccardo","family":"Bertinato","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, \u201cMaggiore della Carit\u00e0\u201d Hospital, University of Piemonte Orientale, 28100 Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renzo Luciano","family":"Boldorini","sequence":"additional","affiliation":[{"name":"Department of Pathology, \u201cMaggiore della Carit\u00e0\u201d Hospital, University of Piemonte Orientale, 28100 Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Giana","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, \u201cMaggiore della Carit\u00e0\u201d Hospital, University of Piemonte Orientale, 28100 Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3993-2895","authenticated-orcid":false,"given":"Felice","family":"Sorrentino","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, 71121 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Nappi","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, 71121 Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5043-6676","authenticated-orcid":false,"given":"Valentino","family":"Remorgida","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, \u201cMaggiore della Carit\u00e0\u201d Hospital, University of Piemonte Orientale, 28100 Novara, Italy"},{"name":"Department of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Surico","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, \u201cMaggiore della Carit\u00e0\u201d Hospital, University of Piemonte Orientale, 28100 Novara, Italy"},{"name":"Department of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/00000478-198307000-00009","article-title":"Aggressive angiomyxoma of the female pelvis and perineum. 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