{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T14:47:12Z","timestamp":1760453232030,"version":"build-2065373602"},"reference-count":27,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T00:00:00Z","timestamp":1694217600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Hypertensive heart disease, especially left ventricular hypertrophy (LVH), is considered to be one of the main types hypertension-mediated organ damage. Hence, the purpose of this study was to examine which method of measuring BP (office BP measurement (OBPM), 24 h ambulatory BP monitoring (ABPM), or home BP monitoring (HBPM)), can be better correlated with echocardiographic LVH in the untreated hypertensive population. Materials and Methods: This study\u2019s population consisted of 202 patients 58 \u00b1 15 years old (40.8% males). All patients reported elevated home BP measurements for at least 3 months, but they had never been treated before for hypertension. Office and out-of-office BP measurements, including ABPM on a usual working day and seven-day HBPM, as well as 2D echocardiography, were performed. Results: In the univariate analysis, LVH was associated (p &lt; 0.05) with a mean 24 h systolic BP (OR: 1.93, CI: 1.29\u20132.91), a mean 24 h diastolic BP (OR: 1.30, CI: 1.16\u20131.80), ambulatory daytime systolic (OR: 1.11, CI:1.01\u20131.82) and diastolic BP (OR: 1.13, CI:1.09\u20131.17), ambulatory nighttime systolic BP (OR: 2.11, CI: 1.04\u20134.31), and mean home systolic BP (OR: 1.05, CI:1.01\u20131.12). Pearson\u2019s correlation analysis showed a significant correlation between the LV mass index and the mean 24 h systolic BP (r = 0.58, p &lt; 0.05), daytime systolic BP (r = 0.59, p &lt; 0.05), and nighttime systolic BP (r = 0.57, p &lt; 0.05). Most of the population with confirmed LVH presented confirmed hypertension (based on ABPM, 48.1% or HBPM, 40%). The second most dominant phenotype was masked hypertension (ABPM, 32.7% and HBPM, 23.7%). The majority (59.3%) had non-dipping status, 20.4% had a reverse dipping pattern, 13% had a dipping pattern, and only 7.3% had extreme dipping BP. Conclusions: Out-of-office BP measurement devices seemed to be superior compared to in-office. This advantage is highlighted by better correlations in the identification of LVH as well as the diagnosis of masked hypertension, a condition also highly correlated with LVH.<\/jats:p>","DOI":"10.3390\/medicina59091636","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T09:00:52Z","timestamp":1694422852000},"page":"1636","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Importance of Out-of-Office Blood Pressure Measurement, as Highlighted by the Correlation with Left Ventricular Hypertrophy in an Untreated Hypertensive Population"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5164-7435","authenticated-orcid":false,"given":"Christina","family":"Antza","sequence":"first","affiliation":[{"name":"3rd Department of Internal Medicine, Aristotle University, Hypertension-24h Ambulatory Blood Pressure Monitoring Center, Papageorgiou Hospital, 56429 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Tziomalos","sequence":"additional","affiliation":[{"name":"1st Cardiology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1081-334X","authenticated-orcid":false,"given":"Georgios","family":"Kostopoulos","sequence":"additional","affiliation":[{"name":"3rd Department of Internal Medicine, Aristotle University, Hypertension-24h Ambulatory Blood Pressure Monitoring Center, Papageorgiou Hospital, 56429 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8110-938X","authenticated-orcid":false,"given":"Christina","family":"Trakatelli","sequence":"additional","affiliation":[{"name":"3rd Department of Internal Medicine, Aristotle University, Hypertension-24h Ambulatory Blood Pressure Monitoring Center, Papageorgiou Hospital, 56429 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasilios","family":"Kotsis","sequence":"additional","affiliation":[{"name":"3rd Department of Internal Medicine, Aristotle University, Hypertension-24h Ambulatory Blood Pressure Monitoring Center, Papageorgiou Hospital, 56429 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1097\/HJH.0000000000001940","article-title":"2018 ESC\/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension","volume":"36","author":"Williams","year":"2018","journal-title":"J. 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