{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:09:07Z","timestamp":1792026547688,"version":"4.4.0"},"reference-count":21,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T00:00:00Z","timestamp":1696636800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Laparoscopic surgery, which results in less bleeding, less postoperative pain, and better cosmetic results, may affect the lung dynamics via the pneumoperitoneum. After laparoscopic surgery, atelectasis develops. The primary aim of the present study is to demonstrate the effects of two different ventilation modes on the development of atelectasis using lung ultrasound, and the secondary outcomes include the plateau pressure, peak inspiratory pressure, and compliance differences between the groups. Materials and Methods: In this study, 62 participants aged 18\u201375 years undergoing laparoscopic cholecystectomy were enrolled. The patients were randomly assigned into two groups: the volume-controlled ventilation (VCV) group (group V) or the pressure-controlled-volume guaranteed ventilation (PCV-VG) group (group PV). The lung ultrasound score (LUS) was obtained thrice: prior to induction (T1), upon the patient\u2019s initial arrival in the recovery room (T2), and just before departing the recovery unit (T3). The hemodynamic data and mechanical ventilation parameters were recorded at different times intraoperatively. Results: The LUS score was similar between the groups at all the times. The change in the LUS score of the right lower anterior chest was statistically higher in the VCV group than the PCV group. The peak inspiratory pressure (PIP) was found to be statistically higher in the V group than the PV group five minutes after induction (T5) (20.84 \u00b1 4.32 p = 0.021). The plateau pressure was found to be higher in the V group than the PV group at all times (after induction (Tind) 17.29 \u00b1 5.53 p = 0.004, (T5) 17.77 \u00b1 4.89 p = 0.001, after pneumoperitoneum (TPP) 19.71 \u00b1 4.28 p = 0.002). Compliance was found to be statistically higher in the PV group than the V group at all times ((Tind) 48.87 \u00b1 15.37 p = 0.011, (T5) 47.94 \u00b1 13.71 p = 0.043, (TPP) 35.65 \u00b1 6.90 p = 0.004). Before and after the pneumoperitoneum, the compliance was determined to be lower in the V group than the PV group, respectively (40.68 \u00b1 13.91 p = 0.043, 30.77 \u00b1 5.73 p = 0.004). Conclusions: LUS score was similar between groups at all times. The PCV-VG mode was superior to the VCV mode in providing optimal ventilatory pressures and maintaining high dynamic compliance in patients undergoing laparoscopic abdominal surgery.<\/jats:p>","DOI":"10.3390\/medicina59101783","type":"journal-article","created":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T14:17:26Z","timestamp":1696688246000},"page":"1783","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Evaluation of the Effect of Pressure-Controlled Ventilation-Volume Guaranteed Mode vs. Volume-Controlled Ventilation Mode on Atelectasis in Patients Undergoing Laparoscopic Surgery: A Randomized Controlled Clinical Trial"],"prefix":"10.3390","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8548-8364","authenticated-orcid":false,"given":"Ayse Zeynep","family":"Turan Civraz","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Kocaeli City Hospital, Kocaeli 41060, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayten","family":"Saracoglu","sequence":"additional","affiliation":[{"name":"College of Medicine, Qatar University, Doha P.O. Box 2713, Qatar"},{"name":"Department of Anesthesiology, ICU and Perioperative Medicine, Aisha Bint Hamad Hospital, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kemal Tolga","family":"Saracoglu","sequence":"additional","affiliation":[{"name":"College of Medicine, Qatar University, Doha P.O. Box 2713, Qatar"},{"name":"Anesthesiology Section, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/anae.13964","article-title":"Intra-operative protective mechanical ventilation in lung transplantation: A randomised, controlled trial","volume":"72","author":"Verbeek","year":"2017","journal-title":"Anaesthesia"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/EJA.0000000000000223","article-title":"Development and validation of a score to predict postoperative respiratory failure in a multicentre European cohort: A prospective, observational study","volume":"32","author":"Canet","year":"2015","journal-title":"Eur. J. Anaesthesiol."},{"key":"ref_3","first-page":"91","article-title":"Postoperative pulmonary changes after laparoscopic cholecystectomy","volume":"55","year":"2001","journal-title":"Med. Arh."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"599","DOI":"10.4103\/0019-5049.165857","article-title":"Post-operative pulmonary complications after non-cardiothoracic surgery","volume":"59","author":"Kelkar","year":"2015","journal-title":"Indian J. Anaesth."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/ALN.0000000000000334","article-title":"Prospective external validation of a predictive score for postoperative pulmonary complications","volume":"121","author":"Mazo","year":"2014","journal-title":"Anesthesiology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1213\/ANE.0b013e3181ba7945","article-title":"Intraoperative ventilatory strategies for prevention of pulmonary atelectasis in obese patients undergoing laparoscopic bariatric surgery","volume":"109","author":"Talab","year":"2009","journal-title":"Anesth. Analg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/ALN.0000000000003943","article-title":"Perioperative Pulmonary Atelectasis: Part I","volume":"136","author":"Zeng","year":"2022","journal-title":"Biol. Mechanisms. Anesthesiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4103\/0019-5049.198406","article-title":"Comparison of volume controlled ventilation and pressure controlled ventilation in patients undergoing robot-assisted pelvic surgeries: An open-label trial","volume":"61","author":"Jaju","year":"2017","journal-title":"Indian J. Anaesth."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jclinane.2016.03.053","article-title":"Comparison of volume-controlled ventilation and pressure-controlled ventilation volume guaranteed during laparoscopic surgery in Trendelenburg position","volume":"34","author":"Assad","year":"2016","journal-title":"J. Clin. Anesth."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"258","DOI":"10.4097\/kjae.2014.67.4.258","article-title":"Volume-controlled versus pressure-controlled ventilation-volume guaranteed mode during one-lung ventilation","volume":"67","author":"Song","year":"2014","journal-title":"Korean J. Anesthesiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1213\/ANE.0000000000001726","article-title":"A Pilot Assessment of 3 Point-of-Care Strategies for Diagnosis of Perioperative Lung Pathology","volume":"124","author":"Ford","year":"2017","journal-title":"Anesth. Analg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1213\/ANE.0000000000001603","article-title":"Lung Ultrasonography for the Assessment of Perioperative Atelectasis: A Pilot Feasibility Study","volume":"124","author":"Monastesse","year":"2017","journal-title":"Anesth. Analg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1164\/rccm.201802-0227LE","article-title":"Training for Lung Ultrasound Score Measurement in Critically Ill Patients","volume":"1198","author":"Rouby","year":"2018","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4137\/CCRPM.S33382","article-title":"Ultrasound for the Pulmonary Consultant","volume":"10","author":"Chichra","year":"2016","journal-title":"Clin. Med. Insights Circ. Respir. Pulm. Med."},{"key":"ref_15","first-page":"206","article-title":"Perioperative Pulmonary Atelectasis: Part II","volume":"136","author":"Lagier","year":"2022","journal-title":"Clin. Implic. Anesthesiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/anae.13640","article-title":"A prospective, cohort evaluation of major and minor airway management complications during routine anaesthetic care at an academic medical centre","volume":"72","author":"Huitink","year":"2017","journal-title":"Anaesthesia"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1097\/00005373-199611000-00007","article-title":"Comparison of volume control and pressure control ventilation: Is flow waveform the difference?","volume":"41","author":"Davis","year":"1996","journal-title":"J. Trauma"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1378\/chest.14-3169","article-title":"Pressure-Controlled vs. Volume-Controlled Ventilation in Acute Respiratory Failure: A Physiology-Based Narrative and Systematic Review","volume":"148","author":"Rittayamai","year":"2015","journal-title":"Chest"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/bja\/aen067","article-title":"Pressure-controlled ventilation improves oxygenation during laparoscopic obesity surgery compared with volume-controlled ventilation","volume":"100","author":"Cadi","year":"2008","journal-title":"Br. J. Anaesth."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.bjan.2019.09.003","article-title":"Comparison of pressure-controlled volume-guaranteed ventilation and volume-controlled ventilation in obese patients during gynecologic laparoscopic surgery in the Trendelenburg position","volume":"69","author":"Toker","year":"2019","journal-title":"Rev. Bras. Anestesiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.jmig.2009.10.007","article-title":"Pressure-controlled vs. volume-controlled ventilation during laparoscopic gynecologic surgery","volume":"17","author":"Bilgin","year":"2010","journal-title":"J. Minim. Invasive Gynecol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/10\/1783\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:02:22Z","timestamp":1760130142000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/10\/1783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,7]]},"references-count":21,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["medicina59101783"],"URL":"https:\/\/doi.org\/10.3390\/medicina59101783","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,7]]}}}