{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T10:46:55Z","timestamp":1776077215284,"version":"3.50.1"},"reference-count":19,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T00:00:00Z","timestamp":1699920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Penile augmentation using filler injections is gaining popularity; however, complications such as foreign body reactions can arise, leading to issues like penile ulceration and necrosis, subsequently necessitating reconstruction. The existing method of the reconstruction of the penis is primarily aimed at filling the deficit. In this paper, we describe a case in which a scrotal flap and autologous augmentation were utilized to treat a soft tissue defect caused by a delayed infection following a penile filler injection. The patient, a 41-year-old male, had received an Aquafilling\u00ae (Biomedica, Prague, Czech Republic) filler injection seven years earlier and later developed a delayed infection. After debridement, the penile defect spanned the entire shaft, and the circumference of the flaccid penis was 7.5 cm. Using a bilateral scrotal flap technique, the lower margins of both flaps were rolled inward after de-epithelialization to achieve autologous augmentation. Over the three-month post-surgery follow-up, neither infections nor flap necrosis were observed. The penile circumference increased to 12 cm, and the patient reported high satisfaction with the outcome. This new surgical technique can be widely applied as treatment for a variety of penile defects.<\/jats:p>","DOI":"10.3390\/medicina59111998","type":"journal-article","created":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T11:03:45Z","timestamp":1699959825000},"page":"1998","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Reconstruction Using a Scrotal Flap with Autologous Augmentation for Delayed Infection Caused by Penile Filler Injection: A Case Report"],"prefix":"10.3390","volume":"59","author":[{"given":"Hee-Jun","family":"Son","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Gil Medical Center, College of Medicine, Gachon University, 24, Incheon 21565, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo-Sik","family":"Pae","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Gil Medical Center, College of Medicine, Gachon University, 24, Incheon 21565, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1093\/asj\/sjac112","article-title":"Motivations and Psychological Characteristics of Men Seeking Penile Girth Augmentation","volume":"42","author":"Sharp","year":"2022","journal-title":"Aesthetic Surg. J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1097\/PRS.0000000000009656","article-title":"Preliminary Application of a Novel Autologous Scrotal Dartos Flap Method for Enlargement of Penile Girth in Men with Small Penis Syndrome","volume":"150","author":"Lei","year":"2022","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1097\/DSS.0000000000002816","article-title":"Nonsurgical Methods for Penile Augmentation: A Systematic Review","volume":"47","author":"Salloum","year":"2021","journal-title":"Dermatol. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"601","DOI":"10.4103\/aja20223","article-title":"Penile augmentation with injectable hyaluronic acid gel: An alternative choice for small penis syndrome","volume":"24","author":"Zhang","year":"2022","journal-title":"Asian J. Androl."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/bju.15145","article-title":"Non-invasive and surgical penile enhancement interventions for aesthetic or therapeutic purposes: A systematic review","volume":"127","author":"Manfredi","year":"2021","journal-title":"BJU Int."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1007\/s00261-020-02788-w","article-title":"Penile girth augmentation by injectable fillers: A comprehensive review of imaging features and inflammatory complications","volume":"46","author":"Badawi","year":"2021","journal-title":"Abdom. Radiol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"124","DOI":"10.14730\/aaps.2015.21.3.124","article-title":"Correcting shape and size using temporary filler after breast augmentation with silicone implants","volume":"21","author":"Shin","year":"2015","journal-title":"Arch. Aesthetic Plast. 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Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1097\/PRS.0b013e3181ead122","article-title":"Complications after polyacrylamide hydrogel injection for soft-tissue augmentation","volume":"126","author":"Ono","year":"2010","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/sj.ijir.3901415","article-title":"Penis invalidating cicatricial outcomes in an enlargement phalloplasty case with polyacrylamide gel (Formacryl)","volume":"18","author":"Parodi","year":"2006","journal-title":"Int. J. Impot. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/aja.2011.29","article-title":"An up-date on penile reconstruction","volume":"13","author":"Garaffa","year":"2011","journal-title":"Asian J. Androl."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"83","DOI":"10.5372\/1905-7415.0801.265","article-title":"Anatomical and functional outcome after bilateral scrotal flap in penile reconstruction","volume":"8","author":"Pungrasmi","year":"2014","journal-title":"Asian Biomed."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/00000637-199610000-00007","article-title":"A new repair technique for penile paraffinoma: Bilateral scrotal flaps","volume":"37","author":"Jeong","year":"1996","journal-title":"Ann. Plast. Surg."},{"key":"ref_16","first-page":"401","article-title":"A Study on the Penile Size of Korea men","volume":"12","author":"Chung","year":"1971","journal-title":"Korean J. Urol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1177\/145749691310200106","article-title":"Pelvic, perineal and genital reconstructions","volume":"102","author":"Kolehmainen","year":"2013","journal-title":"Scand. J. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1093\/asj\/sjx203","article-title":"Surgical Management of Penile Lesions Secondary to Foreign Body Reaction: A Case Report and Systematic Review","volume":"38","author":"Faveret","year":"2018","journal-title":"Aesthet. Surg. J."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/aja.2012.9","article-title":"Penile reconstruction","volume":"15","author":"Garaffa","year":"2013","journal-title":"Asian J. 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