{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:05:08Z","timestamp":1787317508064,"version":"build-2736575974"},"reference-count":24,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T00:00:00Z","timestamp":1700006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Acne scars are one of the most disturbing and long-term symptoms of acne vulgaris, having a negative impact on a person\u2019s physical, emotional, and social well-being. Aim: the purpose of the study was to evaluate the efficacy and post-treatment outcomes of a dual-wavelength system combining the irradiation of two wavelengths at 10,600 nm and 1540 nm in the management of facial atrophic acne scars. Materials and Methods: Four healthy adult volunteers aged 24\u201353 years were enrolled. The areas treated were the full face (two patients), cheeks (one patient), and forehead (one patient). A dual-wavelength system (1540 nm and 10,600 nm) was used for this study. Patients underwent 2\u20134 treatment sessions, and the treatments were performed once every 45\u201390 days. All possible side effects such as burning sensation, dyschromia, mild to moderate post-treatment erythema, bleeding, itching, edema, and crusting were checked. The index to assess edema and erythema was based on a four-point scale (none, mild, moderate, and severe) and was applied before and at 3-month follow-up (3 MFU) after the last treatment session. In addition, a patient assessment was conducted before treatment and at 3 MFU after the last treatment session. Results: For all patients examined, the edema index was mild, while for the erythema index, 3\/4 patients experienced moderate and 1\/4 patients experienced mild symptoms. The mean patient downtime was 5.8 \u00b1 0.5 days. Concerning the patient assessment, 2\/4 subjects showed excellent improvement, 1\/4 patients showed good improvement, and 1\/4 patients showed slight improvement. As shown by the photographic assessment, a noticeable improvement in skin texture and a substantial reduction in acne scars were observed at the end of treatment. Conclusions: This dual-wavelength laser technology has the potential to be an interesting and safe approach for acne scar treatment, with a low risk of scarring\/hypopigmentation and a shorter healing time.<\/jats:p>","DOI":"10.3390\/medicina59112012","type":"journal-article","created":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T01:56:29Z","timestamp":1700099789000},"page":"2012","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["An Innovative Dual-Wavelength Laser Technique for Atrophic Acne Scar Management: A Pilot Study"],"prefix":"10.3390","volume":"59","author":[{"given":"Stefania","family":"Belletti","sequence":"first","affiliation":[{"name":"Private Practice, Studio Kalos, 20100 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5386-7656","authenticated-orcid":false,"given":"Francesca","family":"Madeddu","sequence":"additional","affiliation":[{"name":"El. En. Group, 50041 Calenzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Fabrizio","family":"Amoruso","sequence":"additional","affiliation":[{"name":"Azienda Sanitaria Locale di Crotone, 88816 Strongoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio","family":"Provenzano","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Cosenza Hospital, 87100 Cosenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven Paul","family":"Nistic\u00f2","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University of Rome \u201cLa Sapienza\u201d, 00185 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7264-8808","authenticated-orcid":false,"given":"Irene","family":"Fusco","sequence":"additional","affiliation":[{"name":"El. En. Group, 50041 Calenzano, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0434-1027","authenticated-orcid":false,"given":"Luigi","family":"Bennardo","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,15]]},"reference":[{"key":"ref_1","first-page":"276","article-title":"Acne scarring: A review of cosmetic therapies","volume":"95","author":"LaNoue","year":"2015","journal-title":"Cutis"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/lsm.23484","article-title":"Energy-based devices for the treatment of Acne Scars: 2022 International consensus recommendations","volume":"54","author":"Salameh","year":"2022","journal-title":"Lasers Surg. 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