{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:41:21Z","timestamp":1760150481215,"version":"build-2065373602"},"reference-count":14,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,11,25]],"date-time":"2023-11-25T00:00:00Z","timestamp":1700870400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>The occurrence of pneumorrhachis (PR), defined as the presence of air within the spinal canal, presents a complex clinical picture with diverse etiological factors. We report an exceedingly rare case of PR arising from locally advanced rectal cancer accompanied by a pre-sacral abscess. This report aims to enhance awareness and understanding of rare causes of PR within the medical community, particularly among surgeons engaged in emergency procedures. The patient survived the acute phase of the disease through multiple surgical interventions and admission to the intensive care unit, but succumbed to cardiovascular complications three weeks later. We also offer a brief review of the literature concerning PR originating from the colorectal lumen.<\/jats:p>","DOI":"10.3390\/medicina59122076","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T03:33:56Z","timestamp":1701056036000},"page":"2076","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pneumorrhachis Secondary to a Locally Advanced Rectal Cancer with Pre-Sacral Abscess\u2014Case Report and Review"],"prefix":"10.3390","volume":"59","author":[{"given":"Razvan","family":"Diaconescu","sequence":"first","affiliation":[{"name":"Department of Oncology, Faculty of Medicine, Victor Babe\u015f University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania"},{"name":"Departments of General Surgery, Vasile Goldi\u015f Western University of Arad, 310025 Arad, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2772-7547","authenticated-orcid":false,"given":"Dorel","family":"Popovici","sequence":"additional","affiliation":[{"name":"Department of Oncology, Faculty of Medicine, Victor Babe\u015f University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1772-3910","authenticated-orcid":false,"given":"Cristi","family":"Tarta","sequence":"additional","affiliation":[{"name":"Department X, 2nd Surgical Clinic, Researching Future Chirurgie 2, \u201cVictor Babes\u201d University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Isaic","sequence":"additional","affiliation":[{"name":"Department X, 2nd Surgical Clinic, Researching Future Chirurgie 2, \u201cVictor Babes\u201d University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5944-3522","authenticated-orcid":false,"given":"Dan","family":"Costachescu","sequence":"additional","affiliation":[{"name":"Discipline of Radiology and Medical Imaging, \u201cVictor Babes\u201d University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bogdan","family":"Totolici","sequence":"additional","affiliation":[{"name":"Departments of General Surgery, Vasile Goldi\u015f Western University of Arad, 310025 Arad, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1007\/s00586-006-0160-6","article-title":"Pathogenesis, diagnosis, and management of pneumorrhachis","volume":"15","author":"Oertel","year":"2006","journal-title":"Eur. Spine J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s10140-018-1595-x","article-title":"Causes of pneumocephalus and when to be concerned about it","volume":"25","author":"Cunqueiro","year":"2018","journal-title":"Emerg. Radiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1445-2197.1998.tb04823.x","article-title":"Pneumocephalus resulting from an inflammatory neuro-enteric fistula: A case report","volume":"68","author":"Krishna","year":"1998","journal-title":"Aust. New Zealand J. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e301","DOI":"10.1259\/bjr\/20935250","article-title":"Pneumocephalus as a complication of diverticulitis","volume":"80","author":"Shetty","year":"2007","journal-title":"Br. J. Radiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"216","DOI":"10.2484\/rcr.v3i4.216","article-title":"Pneumoscrotum, pneumomediastinum, pneumothorax, and pneumorrhachis following colon surgery","volume":"3","author":"Anaye","year":"2015","journal-title":"Radiol. Case Rep."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1111\/j.1463-1318.2009.01805.x","article-title":"Pneumospine and pneumocranium\u2014An unusual complication of anastomotic leak: A case report","volume":"12","author":"Warsi","year":"2010","journal-title":"Color. Dis."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3109\/02688697.2010.500420","article-title":"Pneumorrhachis with pneumocranium: An unusual complication of in-tra-abdominal sepsis","volume":"25","author":"Amit","year":"2011","journal-title":"Br. J. Neurosurg."},{"key":"ref_8","first-page":"195","article-title":"The vertebral vein system. Caldwell lecture, 1956","volume":"78","author":"Batson","year":"1957","journal-title":"Am. J. Roentgenol. Radium. Ther. Nucl. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1136\/jnnp.64.1.136","article-title":"Pneumocephalus as a complication of metastases and eroding infection in the sacral region","volume":"64","author":"Willheim","year":"1998","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_10","first-page":"S171","article-title":"Pneumorrhachis","volume":"46","author":"Oertel","year":"2004","journal-title":"Neuroradiology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"3947","DOI":"10.21037\/qims-2022-04","article-title":"The value of magnetic resonance imaging and computed tomography in the study of spinal disorders","volume":"12","year":"2022","journal-title":"Quant. Imaging Med. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1016\/j.asjsur.2021.12.022","article-title":"Magnetic resonance imaging pelvimetry predicts the technical difficulty of rectal surgery","volume":"45","author":"Ma","year":"2022","journal-title":"Asian J. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1016\/j.asjsur.2022.01.026","article-title":"Robotic versus laparoscopic total mesorectal excision for mid-low rectal cancer with difficult anatomical conditions","volume":"45","author":"Pan","year":"2022","journal-title":"Asian J. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/codi.16364","article-title":"Which factors influence the decision to perform Hartmann\u2019s reversal in various causative disease situations? A retrospective cohort study between 2006 and 2021","volume":"25","author":"Katsura","year":"2023","journal-title":"Color. Dis."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/12\/2076\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:30:02Z","timestamp":1760131802000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/59\/12\/2076"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,25]]},"references-count":14,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["medicina59122076"],"URL":"https:\/\/doi.org\/10.3390\/medicina59122076","relation":{},"ISSN":["1648-9144"],"issn-type":[{"type":"electronic","value":"1648-9144"}],"subject":[],"published":{"date-parts":[[2023,11,25]]}}}