{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:45:24Z","timestamp":1760150724293,"version":"build-2065373602"},"reference-count":13,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T00:00:00Z","timestamp":1702944000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Kuraray Co., Ltd."}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Postoperative loss of correction is a concern in cases of distal radius fracture with bone loss after surgery. The purpose of this study was to evaluate the usefulness of a \u03b2-tricalcium phosphate (\u03b2-TCP) with unidirectional pore structure (Affinos\u00ae: Kuraray Co., Ltd, Tokyo, Japan) with internal fixation in patients with bone defects during the correction of distal radius fractures. Thirty-nine patients (40 radii) treated between 2016 and August 2020 were included in the study. There were 8 males and 31 females; the mean age was 70.9 (32\u201388). The mean postoperative observation period was 14.6 (3.4\u201324) months. The bone defect that occurred in the surgery was filled with Affinos\u00ae and fixed with a locking plate. Radial inclination (RI), volar tilt (VT), and ulnar variance (UV) were evaluated after the operation and at the final observation. The start of absorption and the completion of replacement to the host bone of Affinos\u00ae were also evaluated. There were no complications associated with grafts of Affinos\u00ae. The mean time of translucent findings around artificial bone was 1.85 (0.5\u20136) months, and that of complete resorption was 10.6 (1.5\u201316.5) months after surgery. The mean RI was 21.82\u00b0 after surgery and 21.16\u00b0 at final observation. The mean VT was 8.54\u00b0 after surgery and 8.50\u00b0 at final observation. The mean UV was \u22120.3 mm after surgery and 0.5 mm at final observation. Affinos\u00ae was resorbed relatively early, and host bone formation was observed. Filling of unidirectional pore structure \u03b2-TCP with internal fixation showed favorable outcomes in the surgery of distal radius fractures with bone defects.<\/jats:p>","DOI":"10.3390\/medicina60010001","type":"journal-article","created":{"date-parts":[[2023,12,19]],"date-time":"2023-12-19T04:18:37Z","timestamp":1702959517000},"page":"1","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Outcomes of a Novel Unidirectional Porous \u03b2-Tricalcium Phosphate Filling in Distal Radius Fracture with Volar Locking Plate Fixation: Secondary Publication of the Japanese Version"],"prefix":"10.3390","volume":"60","author":[{"given":"Yoshito","family":"Sudo","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Gifu Prefectural Tajimi Hospital, Gifu 507-8522, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7511-6388","authenticated-orcid":false,"given":"Yoshihiro","family":"Nishida","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya 466-8550, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroatsu","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Gifu Prefectural Tajimi Hospital, Gifu 507-8522, Japan"},{"name":"Medical Corporation Rokujukai, Goto Orthopaedic Clinic, Tsuhima 496-0072, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Gifu Prefectural Tajimi Hospital, Gifu 507-8522, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuro","family":"Takatsu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Gifu Prefectural Tajimi Hospital, Gifu 507-8522, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1177\/2151458511426874","article-title":"Aspects of current management of distal radius fractures in the elderly individuals","volume":"2","author":"Arora","year":"2011","journal-title":"Geriatr. 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Disord., 21.","DOI":"10.1186\/s12891-020-03203-7"},{"key":"ref_5","first-page":"e7465","article-title":"A novel unidirectional porous\u03b2-tricalcium phosphate bone substitute in orthopedic surgery: A technical note and case illustrations","volume":"12","author":"Funayama","year":"2020","journal-title":"Cureus"},{"key":"ref_6","first-page":"2","article-title":"The use of unidirectional porous \u03b2-tricalcium phosphate in surgery for calcaneal fractures: A report of four cases","volume":"10","author":"Izawa","year":"2017","journal-title":"Foot Ankle Online J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"211","DOI":"10.2185\/jrm.3017","article-title":"A novel unidirectional porous \u03b2-tricalcium phosphate grafting for vertebral fracture in the elderly: Preliminary case series","volume":"14","author":"Funayama","year":"2019","journal-title":"J. Rural Med."},{"key":"ref_8","first-page":"59","article-title":"Unidirectional porous \u03b2-tricalcium phosphate: A new bone filling substitute for treatment of distal radius fracture in elderly population","volume":"25","author":"Muramatsu","year":"2020","journal-title":"J. Hand Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1142\/S0218810411005023","article-title":"Use of the volar fixed angle plate for comminuted distal radius fractures and augmentation with a hydroxyapatite bone graft substitute","volume":"16","author":"Goto","year":"2011","journal-title":"Hand Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.jhsa.2018.05.028","article-title":"The Effect of Osteoporosis on the Outcomes After Volar Locking Plate Fixation in Female Patients Older than 50 Years with Unstable Distal Radius Fractures","volume":"43","author":"Lee","year":"2018","journal-title":"J. Hand Surg. Am."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/BOT.0000000000000519","article-title":"Volar Locking Plate or External Fixation with Optional Addition of K-Wires for Dorsally Displaced Distal Radius Fractures: A Randomized Controlled Study","volume":"30","author":"Navarro","year":"2016","journal-title":"J. Orthop. Trauma"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.2106\/JBJS.H.00722","article-title":"Unstable distal radial fractures treated with external fixation, a radial column plate, or a volar plate. A prospective randomized trial","volume":"91","author":"Wei","year":"2009","journal-title":"J. Bone Jt. Surg."},{"key":"ref_13","first-page":"596","article-title":"Clinical outcomes of a novel unidirectional porous \u03b2-tricalcium phosphate filling in distal radius fracture with volar locking plate fixation","volume":"44","author":"Sudo","year":"2022","journal-title":"J. Jpn. Soc. Fract. Repair"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/1\/1\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:41:10Z","timestamp":1760132470000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/1\/1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,19]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1]]}},"alternative-id":["medicina60010001"],"URL":"https:\/\/doi.org\/10.3390\/medicina60010001","relation":{},"ISSN":["1648-9144"],"issn-type":[{"type":"electronic","value":"1648-9144"}],"subject":[],"published":{"date-parts":[[2023,12,19]]}}}