{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T17:12:21Z","timestamp":1774631541398,"version":"3.50.1"},"reference-count":27,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T00:00:00Z","timestamp":1703894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Taichung Armed Forces General Hospital","award":["TCAFGH-D-112015"],"award-info":[{"award-number":["TCAFGH-D-112015"]}]},{"name":"Taichung Armed Forces General Hospital","award":["TCAFGH-E-112048"],"award-info":[{"award-number":["TCAFGH-E-112048"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Systemic lupus erythematosus (SLE) is a disease with multiple organ involvement, and spontaneous hemorrhage, especially perirenal hemorrhage, is rare. Case Presentation: We report the case of a 19-year-old teenager with SLE who experienced left flank pain and hypovolemic shock. Abdominal computed tomography revealed a large left retroperitoneal hematoma. Recurrent hypovolemic shock occurred despite the transcatheter arterial embolization of the left renal artery. Repetitive abdominal computed tomography results showed active hemorrhage. Result: An exploratory laparotomy was used to confirm descending colonic mesenteric artery bleeding, which was resolved. The patient needed temporary regular kidney replacement therapy for active lupus nephritis, which terminated one month after discharge. Conclusions: When patients with SLE experience acute abdominal pain, flank pain, or back pain combined with hypovolemia, there is a higher risk of bleeding due to spontaneous hemorrhage, which should be included in the differential diagnosis. Therefore, early diagnosis and adequate emergency intervention are necessary.<\/jats:p>","DOI":"10.3390\/medicina60010078","type":"journal-article","created":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T06:37:12Z","timestamp":1704004632000},"page":"78","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Spontaneous Retroperitoneal Bleeding in a Patient with Systemic Lupus Erythematosus"],"prefix":"10.3390","volume":"60","author":[{"given":"Wei-Hung","family":"Chen","sequence":"first","affiliation":[{"name":"Division of Rheumatology\/Immunology\/Allergy, Department of Internal Medicine, Taichung Armed-Forces General Hospital, Taichung 411, Taiwan"},{"name":"Division of Rheumatology\/Immunology\/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8092-274X","authenticated-orcid":false,"given":"Deng-Ho","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Rheumatology\/Immunology\/Allergy, Department of Internal Medicine, Taichung Armed-Forces General Hospital, Taichung 411, Taiwan"},{"name":"Division of Rheumatology\/Immunology\/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan"},{"name":"Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology, Taichung 406, Taiwan"},{"name":"Institute of Biomedical Science, National Chung-Hsing University, Taichung 402, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1038\/ki.1996.175","article-title":"Lupus autoantibodies interact directly with distinct glomerular and vascular cell surface antigens","volume":"49","author":"Kleyman","year":"1996","journal-title":"Kidney Int."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1038\/ki.1992.242","article-title":"Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites","volume":"41","author":"Vlahakos","year":"1992","journal-title":"Kidney Int."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1002\/art.21314","article-title":"Incidence rates of arterial and venous thrombosis after diagnosis of systemic lupus erythematosus","volume":"53","author":"Sarabi","year":"2005","journal-title":"Arthritis Care Res. 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