{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,4]],"date-time":"2026-01-04T10:45:47Z","timestamp":1767523547271,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>We present a case of endogenous endophthalmitis with urinary tract infection (UTI) caused by group B Streptococcus (GBS). An 86-year-old female initially presented with ocular pain and sudden visual disturbance of the left eye. The patient did not complain of other symptoms and had no history of recent ocular surgery or trauma. Endogenous endophthalmitis was clinically diagnosed based on ophthalmic examination, history, and lab results showing systemic infection. A few days later, GBS was identified in her aqueous humor, blood, and urine cultures. Intravitreal ceftazidime and vancomycin injections, as well as fortified ceftazidime and vancomycin eye drops, were used immediately after clinical diagnosis. However, the symptoms worsened despite repeated intravitreal injections, so evisceration was performed. Endogenous endophthalmitis caused by GBS is very virulent and may present without evident systemic symptoms. The early recognition of the disease and systemic work up, followed by prompt treatment, is necessary.<\/jats:p>","DOI":"10.3390\/medicina60050700","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T09:26:02Z","timestamp":1714123562000},"page":"700","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Endogenous Endophthalmitis from Urinary Tract Infection Caused by Group B Streptococcus: A Case Report"],"prefix":"10.3390","volume":"60","author":[{"given":"Heejeong","family":"You","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3717-2223","authenticated-orcid":false,"given":"Joonhyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam 13496, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1097\/00055735-200112000-00012","article-title":"Endogenous endophthalmitis","volume":"12","author":"Chee","year":"2001","journal-title":"Curr. Opin. Ophthalmol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0039-6257(03)00054-7","article-title":"Endogenous bacterial endophthalmitis: A 17-year prospective series and review of 267 reported cases","volume":"48","author":"Jackson","year":"2003","journal-title":"Surv. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/S0161-6420(00)00216-5","article-title":"Endogenous bacterial endophthalmitis: An East Asian experience and a reappraisal of a severe ocular affliction","volume":"107","author":"Wong","year":"2000","journal-title":"Ophthalmology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/S0161-6420(02)01225-3","article-title":"Group B Streptococcus endogenous endophthalmitis: Case reports and review of the literature","volume":"109","author":"Lee","year":"2002","journal-title":"Ophthalmology"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Yoshida, M., Yokokura, S., Nishida, T., Mochizuki, K., Suzuki, T., Maruyama, K., Otomo, T., Nishiguchi, K.M., Kunikata, H., and Nakazawa, T. (2020). Endogenous endophthalmitis caused by group B streptococcus; case reports and review of 35 reported cases. BMC Ophthalmol., 20.","DOI":"10.1186\/s12886-020-01378-0"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"28100","DOI":"10.1038\/srep28100","article-title":"Risk factors for endophthalmitis requiring evisceration or enucleation","volume":"6","author":"Lu","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"8869590","DOI":"10.1155\/2020\/8869590","article-title":"Endogenous Endophthalmitis: A Review of Case Series Published between 2011 and 2020","volume":"2020","author":"Danielescu","year":"2020","journal-title":"J. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/aos.15245","article-title":"When is vitrectomy for endophthalmitis needed?","volume":"101","author":"Kuhn","year":"2023","journal-title":"Acta Ophthalmol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1177\/11206721211021185","article-title":"Complete and early vitrectomy for endophthalmitis","volume":"31","author":"Morris","year":"2021","journal-title":"Eur. J. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"390","DOI":"10.3341\/kjo.2022.0014","article-title":"Immediate Vitrectomy for Acute Endophthalmitis in Patients with a Visual Acuity of Hand Motion or Better","volume":"36","author":"Kim","year":"2022","journal-title":"Korean J. Ophthalmol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3341\/kjo.2017.0036","article-title":"Endophthalmitis","volume":"31","author":"Sheu","year":"2017","journal-title":"Korean J. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s15010-022-01879-8","article-title":"First Italian report of a liver abscess and metastatic endogenous endophthalmitis caused by ST-23 hypervirulent Klebsiella pneumoniae in an immunocompetent individual","volume":"51","author":"Tiecco","year":"2023","journal-title":"Infection"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Gajdzis, M., Figu\u0142a, K., Kami\u0144ska, J., and Kaczmarek, R. (2022). Endogenous Endophthalmitis-The Clinical Significance of the Primary Source of Infection. J. Clin. Med., 11.","DOI":"10.3390\/jcm11051183"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1007\/s00417-017-3760-4","article-title":"59 eyes with endogenous endophthalmitis- causes, outcomes and mortality in a Danish population between 2000 and 2016","volume":"255","author":"Bjerrum","year":"2017","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.survophthal.2014.06.002","article-title":"Systematic review of 342 cases of endogenous bacterial endophthalmitis","volume":"59","author":"Jackson","year":"2014","journal-title":"Surv. Ophthalmol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12348-018-0158-3","article-title":"Endogenous endophthalmitis: A 9-year retrospective study at a tertiary referral hospital in Malaysia","volume":"8","author":"Muda","year":"2018","journal-title":"J. Ophthalmic Inflamm. Infect."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1081\/JDI-120013971","article-title":"Unusual Clinical Presentation of Klebsiella Pneumoniae Induced Endogenous Endophthalmitis and Xanthogranulomatous Pyelonephritis In a Non-Nephrolithiasis and Non-Obstructive Urinary Tract","volume":"24","author":"Lin","year":"2002","journal-title":"Ren. Fail."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1097\/IAE.0b013e318228e312","article-title":"Changes in the Clinical Features and Prognostic Factors of Endogenous Endophthalmitis: Fifteen Years of Clinical Experience in Korea","volume":"32","author":"Lee","year":"2012","journal-title":"Retina"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e36139","DOI":"10.1097\/MD.0000000000036139","article-title":"Endogenous endophthalmitis caused by urinary tract infection: A case report","volume":"102","author":"Ren","year":"2023","journal-title":"Medicine"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/5\/700\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:33:43Z","timestamp":1760106823000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/5\/700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,25]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,5]]}},"alternative-id":["medicina60050700"],"URL":"https:\/\/doi.org\/10.3390\/medicina60050700","relation":{},"ISSN":["1648-9144"],"issn-type":[{"type":"electronic","value":"1648-9144"}],"subject":[],"published":{"date-parts":[[2024,4,25]]}}}