{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T06:10:35Z","timestamp":1776751835015,"version":"3.51.2"},"reference-count":68,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objective: Interatrial block (IAB) is defined as a conduction delay between the right and left atria. No data are available about the prevalence of both partial IAB and advanced IAB among the different stages of chronic kidney disease. The aim of this study was to describe the prevalence and type of advanced IAB across the spectrum of renal function, including patients on dialysis and the clinical characteristics associated with advanced IAB. Materials and Methods: Retrospective, single-center study of 151 patients consecutively admitted to the Nephrology and Ophthalmology Unit for 3 months. The study population was divided into three groups according to stages of chronic kidney disease. We evaluated the prevalence and pattern of IAB among the groups and the clinical characteristics associated with advanced IAB. Results: The prevalence of partial IAB was significantly lower in end-stage kidney disease (ESKD) group compared to control group (36.7% vs. 59.6%; p = 0.02); in contrast the prevalence of advanced IAB was significantly higher in both chronic kidney disease (CKD) (17.8% vs. 5.3%, p = 0.04) and ESKD group (24.5% vs. 5.3%, p = 0.005) compared to control group. The atypical pattern of advanced IAB was more frequent in both the ESKD and CKD group than in the control group (100% and 75% vs. 33.3%; p = 0.02). Overall, among patients that showed advanced IAB, 17 (73.9%) showed an atypical pattern by morphology and 2 (8.7%) showed an atypical pattern by duration of advanced IAB. The ESKD group was younger than the control group (65.7 \u00b1 12.3 years vs. 71.3 \u00b1 9.9 years; p = 0.01) and showed a higher prevalence of beta blockers (42.9% vs. 19.3%; p = 0.009), as in the CKD group (37.8% vs. 19.3%; p= 0.04). Conclusions: The progressive worsening of renal function was associated with an increasing prevalence of advanced IAB. Advanced IAB may be a sign of uremic cardiomyopathy and may suggest further evaluation with long-term follow-up to investigate its prognostic significance in chronic kidney disease.<\/jats:p>","DOI":"10.3390\/medicina60061001","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T04:21:28Z","timestamp":1718770888000},"page":"1001","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Advanced Interatrial Block across the Spectrum of Renal Function"],"prefix":"10.3390","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3982-1987","authenticated-orcid":false,"given":"Marco","family":"Marano","sequence":"first","affiliation":[{"name":"Unit of Nephrology and Dialysis, Maria Rosaria Clinic, Via Colle San Bartolomeo, 80045 Pompei, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Senigalliesi","sequence":"additional","affiliation":[{"name":"Unit of Nephrology and Dialysis, Maria Rosaria Clinic, Via Colle San Bartolomeo, 80045 Pompei, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossella","family":"Cocola","sequence":"additional","affiliation":[{"name":"Unit of Nephrology and Dialysis, Maria Rosaria Clinic, Via Colle San Bartolomeo, 80045 Pompei, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariarosaria","family":"Fontana","sequence":"additional","affiliation":[{"name":"Unit of Nephrology and Dialysis, Maria Rosaria Clinic, Via Colle San Bartolomeo, 80045 Pompei, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1246-4876","authenticated-orcid":false,"given":"Erika","family":"Parente","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Medical Translational Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, Monaldi Hospital, Via Leonardo Bianchi, 80126 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9227-0360","authenticated-orcid":false,"given":"Vincenzo","family":"Russo","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Medical Translational Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, Monaldi Hospital, Via Leonardo Bianchi, 80126 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.jelectrocard.2012.06.029","article-title":"Interatrial blocks. A separate entity from left atrial enlargement: A consensus report","volume":"45","author":"Platonov","year":"2012","journal-title":"J. Electrocardiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1378\/chest.65.3.252","article-title":"Atrial ultrastructure in patients with fixed intra-atrial block","volume":"65","author":"Legato","year":"1974","journal-title":"Chest"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1016\/j.amjcard.2016.03.013","article-title":"Electrocardiographic advanced interatrial block and atrial fibrillation risk in the general population","volume":"117","author":"Zhang","year":"2016","journal-title":"Am. J. Cardiol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e008247","DOI":"10.1161\/JAHA.117.008247","article-title":"Risk prediction of atrial fibrillation based on electrocardiographic interatrial block","volume":"7","author":"Skov","year":"2018","journal-title":"J. Am. Heart Assoc."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1076-7460.2006.04518.x","article-title":"Prevalence of interatrial block in the Program of All-Inclusive Care for the Elderly (PACE)","volume":"15","author":"Ariyarajah","year":"2006","journal-title":"Am. J. Geriatr. Cardiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.hrthm.2015.10.034","article-title":"Interatrial block and atrial arrhythmias in centenarians: Prevalence, associations, and clinical implications","volume":"13","author":"Roessel","year":"2016","journal-title":"Heart Rhythm"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.jacc.2022.01.030","article-title":"Cardiovascular Complications of Interatrial Conduction Block: JACC State-of-the-Art Review","volume":"79","author":"Power","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e90","DOI":"10.1016\/j.hrthm.2015.12.041","article-title":"Letter to the editor\u2014Prevalence of interatrial block during lifetime","volume":"13","author":"Russo","year":"2016","journal-title":"Heart Rhythm"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.nmd.2018.01.010","article-title":"Interatrial block to predict atrial fibrillation in myotonic dystrophy type 1","volume":"28","author":"Russo","year":"2018","journal-title":"Neuromuscul. Disord."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e13781","DOI":"10.1111\/eci.13781","article-title":"The prognostic role of interatrial block among COVID-19 patients hospitalized in medicine wards","volume":"52","author":"Russo","year":"2022","journal-title":"Eur. J. Clin. Investig."},{"key":"ref_11","first-page":"841","article-title":"Analysis of the Association Between Electrocardiographic P-wave Characteristics and Atrial Fibrillation in the REGICOR Study","volume":"70","author":"Grau","year":"2017","journal-title":"Rev. Espa\u00f1ola Cardiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/S0002-9149(03)00027-4","article-title":"Association of interatrial block with development of atrial fibrillation","volume":"91","author":"Agarwal","year":"2003","journal-title":"Am. J. Cardiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1542-474X.2009.00341.x","article-title":"Abnormal P wave morphology is a predictor of atrial fibrillation in MADIT II patients","volume":"15","author":"Holmqvist","year":"2010","journal-title":"Ann. Noninvasive Electrocardiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s11255-012-0187-z","article-title":"Electrocardiographic P-wave characteristics in patients with end-stage renal disease: P-index and interatrial block","volume":"45","author":"Solak","year":"2013","journal-title":"Int. Urol. Nephrol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e13053","DOI":"10.1111\/anec.13053","article-title":"New electrocardiographic aspects of the P wave: Its value in clinical cardiology","volume":"28","author":"Bacharova","year":"2023","journal-title":"Ann. Noninvasive Electrocardiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s11255-015-0914-3","article-title":"Prevalence and determinants of interatrial block in hemodialysis patients","volume":"47","author":"Marano","year":"2015","journal-title":"Int. Urol. Nephrol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1093\/europace\/euaa114","article-title":"Advanced interatrial block and P-wave duration are associated with atrial fibrillation and stroke in older adults with heart disease: The BAYES registry","volume":"22","author":"Elosua","year":"2020","journal-title":"EP Europace"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.jacep.2023.04.006","article-title":"Interatrial Block Association with Adverse Cardiovascular Outcomes in Patients Without a History of Atrial Fibrillation","volume":"9","author":"Lampert","year":"2023","journal-title":"Clin. Electrophysiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/07853890.2020.1731759","article-title":"The prevalence and prognostic significance of interatrial block in the general population","volume":"52","author":"Istolahti","year":"2020","journal-title":"Ann. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ijcard.2020.08.006","article-title":"Interatrial block and cognitive impairment in the BAYES prospective registry","volume":"321","author":"Ibarrola","year":"2020","journal-title":"Int. J. Cardiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"e014553","DOI":"10.1161\/JAHA.119.014553","article-title":"Association of abnormal P-wave indices with dementia and cognitive decline over 25 years: ARIC-NCS (the atherosclerosis risk in communities neurocognitive study)","volume":"8","author":"Gutierrez","year":"2019","journal-title":"J. Am. Heart Assoc."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.amjcard.2020.09.008","article-title":"Relation of Interatrial Block to Cognitive Impairment in Patients \u2265 70 Years of Age (From the CAMBIAD Case-control Study)","volume":"136","author":"Herrera","year":"2020","journal-title":"Am. J. Cardiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"ytad532","DOI":"10.1093\/ehjcr\/ytad532","article-title":"Interatrial block as a first clinical presentation of atrial cardiomyopathy related to a novel LMNA variant: A case report","volume":"7","author":"Iavarone","year":"2023","journal-title":"Eur. Heart J. Case Rep."},{"key":"ref_24","first-page":"561","article-title":"Interatrial block: An under-recognized electrocardiographic diagnosis with important clinical-therapeutic implications","volume":"15","author":"Proietti","year":"2014","journal-title":"G. Ital. Cardiol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/j.amjcard.2017.01.012","article-title":"Relation of prolonged P-wave duration to risk of sudden cardiac death in the general population (from the atherosclerosis risk in communities study)","volume":"119","author":"Maheshwari","year":"2017","journal-title":"Am. J. Cardiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.hrthm.2010.09.020","article-title":"P wave duration is associated with cardiovascular and all-cause mortality outcomes: The national health and nutrition examination survey","volume":"8","author":"Magnani","year":"2011","journal-title":"Heart Rhythm"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/hdi.12403","article-title":"Advanced interatrial block in hemodialysis patients","volume":"20","author":"Marano","year":"2016","journal-title":"Hemodial. Int."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-0736(85)80029-7","article-title":"Electrocardiographic and vectorcardiographic study of interatrial conduction disturbances with left atrial retrograde activation","volume":"18","author":"Trilla","year":"1985","journal-title":"J. Electrocardiol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.echo.2014.10.003","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: An update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"28","author":"Lang","year":"2015","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1136\/heartjnl-2011-300069","article-title":"Left atrial function: Pathophysiology, echocardiographic assessment, and clinical applications","volume":"97","author":"Rosca","year":"2011","journal-title":"Heart"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1161\/01.CIR.92.4.835","article-title":"Left Atrial Size and the Risk of Stroke and Death\u2014The Framingham Heart-Study","volume":"92","author":"Benjamin","year":"1995","journal-title":"Circulation"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1161\/CIRCIMAGING.108.826602","article-title":"Left Atrial Volume and Geometry in Healthy Aging the Cardiovascular Health Study","volume":"2","author":"Aurigemma","year":"2009","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1093\/ehjci\/jet284","article-title":"Echocardiographic reference ranges for normal cardiac chamber size: Results from the NORRE study","volume":"15","author":"Kou","year":"2014","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"611644","DOI":"10.1093\/ehjci\/jet105","article-title":"Recommendations for the echocardiographic assessment of native valvular regurgitation: An executive summary from the European Association of Cardiovascular Imaging","volume":"14","author":"Lancellotti","year":"2013","journal-title":"Eur. Heart J. Cardiovasc. Imaging"},{"key":"ref_35","first-page":"223244","article-title":"European Association of Echocardiography recommendation for the assessment of valvular regurgitation. Part 1: Aortic and pulmonary regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur. J. Echocardiogr."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"303371","DOI":"10.1016\/j.echo.2017.01.007","article-title":"Recommendations for noninvasive evaluation of native valvular regurgitation: A report from the American Society of Echocardiography developed in collaboration with the Society for Cardiovascular Magnetic Resonance","volume":"30","author":"Zoghbi","year":"2017","journal-title":"J. Am. Soc. Echocardiogr."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1053\/eupc.2002.0221","article-title":"Morphology of inter-atrial conduction routes in patients with atrial fibrillation","volume":"4","author":"Platonov","year":"2002","journal-title":"Europace"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s10840-018-0413-4","article-title":"Intra- and interatrial conduction abnormalities: Hemodynamic and arrhythmic significance","volume":"52","author":"Johner","year":"2018","journal-title":"J. Interv. Card. Electrophysiol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/kisup.2012.64","article-title":"Definition and classification of CKD","volume":"3","author":"Decreased","year":"2013","journal-title":"Kidney Int."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1053\/ajkd.2003.50007","article-title":"Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey","volume":"41","author":"Coresh","year":"2003","journal-title":"Am. J. Kidney Dis."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0140-6736(13)60595-4","article-title":"Chronic kidney disease and cardiovascular risk: Epidemiology, mechanisms, and prevention","volume":"382","author":"Gansevoort","year":"2013","journal-title":"Lancet"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1038\/s41581-022-00616-6","article-title":"Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease","volume":"18","author":"Matsushita","year":"2022","journal-title":"Nat. Rev. Nephrol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1161\/CIRCULATIONAHA.106.678342","article-title":"Chronic kidney disease: Eff ects on the cardiovascular system","volume":"116","author":"Schiffrin","year":"2007","journal-title":"Circulation"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"501","DOI":"10.2215\/CJN.04231206","article-title":"Kidney function, electrocardiographic findings, and cardiovascular events among older adults","volume":"2","author":"Kestenbaum","year":"2007","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1681\/ASN.2014101045","article-title":"Electrocardiographic Measures and Prediction of Cardiovascular and Noncardiovascular Death in CKD","volume":"27","author":"Deo","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Park, S., Yum, Y., Cha, J.J., Joo, H.J., Park, J.H., Hong, S.J., Yu, C.W., and Lim, D.S. (2022). Prevalence and Clinical Impact of Electrocardiographic Abnormalities in Patients with Chronic Kidney Disease. J. Clin. Med., 11.","DOI":"10.21203\/rs.3.rs-1507372\/v1"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1093\/eurheartj\/ehy060","article-title":"Chronic kidney disease and arrhythmias: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference","volume":"39","author":"Turakhia","year":"2018","journal-title":"Eur. Heart J."},{"key":"ref_48","unstructured":"National Institute of Diabetes and Digestive and Kidney Diseases (2006). 2006 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States, Bethesda, MD, Cardiovascular Special Studies."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/S0085-2538(15)50904-6","article-title":"Survival of dialysis patients after cardiac arrest and the impact of implantable cardioverter defibrillators","volume":"68","author":"Herzog","year":"2005","journal-title":"Kidney Int."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1093\/ndt\/17.12.2170","article-title":"Hemodialysis increase QTc interval but not QTc dispersion in ESRD patients without manifest cardiac disease","volume":"17","author":"Covic","year":"2002","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_51","first-page":"460","article-title":"Changes in QT intervals in patients with end-stage renal disease before and after hemodialysis","volume":"21","author":"Malhis","year":"2010","journal-title":"Saudi J. Kidney Dis. Transplant."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1177\/000331970005100607","article-title":"Increased QT interval dispersion after hemodialysis: Role of peridialytic electrolyte gradients","volume":"51","author":"Yetkin","year":"2000","journal-title":"Angiology"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0022-0736(98)80070-8","article-title":"Cellular basis for QT dispersion","volume":"30","author":"Antzelevitch","year":"1998","journal-title":"J. Electrocardiol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1681\/ASN.V1061297","article-title":"QT Dispersion in Patients with End-Stage Renal Failure and during Hemodialysis","volume":"10","author":"Zilahi","year":"1999","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"257","DOI":"10.12659\/AOT.889927","article-title":"Associations of ECG interval prolongations with mortality among ESRD patients evaluated for renal transplantation","volume":"19","author":"Patzer","year":"2014","journal-title":"Ann. Transplant."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"949","DOI":"10.2215\/CJN.07440711","article-title":"Electrocardiogram abnormalities and cardiovascular mortality in elderly patients with CKD","volume":"7","author":"Dobre","year":"2012","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1157\/13123993","article-title":"An\u00e1lisis de la prevalencia y los factores predisponentes de los bloqueos de rama en los pacientes que inician di\u00e1lisis [Prevalence of and predisposing factors for bundle branch block in patients starting dialysis]","volume":"61","year":"2008","journal-title":"Rev. Esp. Cardiol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.recesp.2021.05.016","article-title":"Left Atrial Enlargement in Competitive Athletes and Atrial Electrophysiology","volume":"75","author":"Herrera","year":"2022","journal-title":"Rev. Esp. Cardiol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0002-9149(77)80209-9","article-title":"Electrocardiographic left atrial enlargement. Electrophysiologic, echocardiographic and haemodynamic correlates","volume":"39","author":"Josephson","year":"1977","journal-title":"Am. J. Cardiol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"54","DOI":"10.15420\/ecr.2015.10.01.54","article-title":"The Diagnosis and Clinical Implications of Interatrial Block","volume":"10","author":"Robledo","year":"2015","journal-title":"Eur. Cardiol."},{"key":"ref_61","first-page":"161","article-title":"Diagnosis of interatrial block","volume":"14","author":"Baranchuk","year":"2017","journal-title":"J. Geriatr. Cardiol."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Bejarano-Arosemena, R., and Mart\u00ednez-Sell\u00e9s, M. (2023). Interatrial Block, Bay\u00e9s Syndrome, Left Atrial Enlargement, and Atrial Failure. J. Clin. Med., 12.","DOI":"10.3390\/jcm12237331"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/pace.13895","article-title":"Interatrial Block Can Occur in the Absence of Left Atrial Enlargement: New Experimental Model","volume":"43","author":"Guerra","year":"2020","journal-title":"Pacing Clin. Electrophysiol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s11255-020-02430-0","article-title":"Echocardiographic predictors of interatrial block in patients with severe chronic kidney disease","volume":"52","author":"Yetim","year":"2020","journal-title":"Int. Urol. Nephrol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1093\/europace\/euq042","article-title":"Alterations of atrialelectrophysiologyinduced by electrolytevariations: Combinedcomputational and P-waveanalysis","volume":"12","author":"Severi","year":"2010","journal-title":"Europace"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/anec.12252","article-title":"Hemodialysis affects interatrial conduction","volume":"20","author":"Marano","year":"2015","journal-title":"Ann. Noninvasive Electrocardiol."},{"key":"ref_67","first-page":"468493","article-title":"Second-degree interatrial block in hemodialysis patients","volume":"2015","author":"Enriquez","year":"2015","journal-title":"Case Rep. Cardiol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"e12583","DOI":"10.1111\/anec.12583","article-title":"Second-degree interatrial block: Brief review and concept","volume":"23","author":"Baranchuk","year":"2018","journal-title":"Ann. Noninvasive Electrocardiol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/6\/1001\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:00:48Z","timestamp":1760108448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/6\/1001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,18]]},"references-count":68,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,6]]}},"alternative-id":["medicina60061001"],"URL":"https:\/\/doi.org\/10.3390\/medicina60061001","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,18]]}}}