{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:14:07Z","timestamp":1760145247932,"version":"build-2065373602"},"reference-count":24,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Peri-acetabular metastases often lead to significant pain and functional impairment. Surgical interventions, including the Harrington procedure, aim to address these challenges. This study evaluates a modified Harrington procedure using the MUTARS\u00ae PRS\u00ae (Pelvic Revision Shell) with an 8 mm fixation screw for severe acetabular defects resulting from metastatic lesions. Materials and Methods: Retrospective analysis of 12 patients treated between January 2020 and December 2023 was conducted. The procedure involved using the novel MUTARS\u00ae PRS\u00ae with an 8 mm in diameter dome screw (length 70\u2013100 mm). Outcome measures included implant positioning changes, complication rates, functional outcomes, implant longevity, and patient survival. Radiological assessments were performed postoperatively, with follow-ups at 3, 6, 12 months, and annually thereafter. Results: Average follow-up was 15 \u00b1 11 months, with 67% patient survival at 1 year and 44% at 2 years. Implant survivorship remained 100%. Harris Hip Score improved significantly from 37 \u00b1 22 preoperatively to 75 \u00b1 15 at the last follow-up. No revisions involving implant components were reported. Complications occurred in 5 of 12 patients. Overall, PRS\u00ae demonstrates effective osseous ingrowth, high primary stability, immediate full weight-bearing, and low complication rates. Conclusions: PRS\u00ae integrates facilitating osseous ingrowth for preferable long-term outcomes, while efficiently transmitting the weight-bearing load to the intact aspect of the pelvis using a long 8 mm lever screw, enhancing the primary stability of the construct. It proves to be an effective and reproducible technique for managing destructive metastatic lesions of the acetabulum and peri-acetabular region, even in irradiated bone.<\/jats:p>","DOI":"10.3390\/medicina60071047","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T09:29:33Z","timestamp":1719394173000},"page":"1047","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Modified Harrington Procedure for Metastatic Peri-Acetabular Bone Lesion Using a Novel Highly Porous Titanium Revision Shell with Long Lever Arm Screw"],"prefix":"10.3390","volume":"60","author":[{"given":"Sven","family":"Frieler","sequence":"first","affiliation":[{"name":"Department of Tumour Orthopaedics and Revision Arthroplasty, Orthopaedic Hospital Volmarstein, 58300 Wetter, Germany"},{"name":"Department of Trauma and Orthopaedic Surgery, BG University Hospital Bergmannsheil, Ruhr University Bochum, 44801 Bochum, Germany"},{"name":"Seattle Science Foundation, Seattle, WA 98122, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carsten","family":"Gebert","sequence":"additional","affiliation":[{"name":"Department of Tumour Orthopaedics and Revision Arthroplasty, Orthopaedic Hospital Volmarstein, 58300 Wetter, Germany"},{"name":"Department of Orthopedics and Tumor Orthopedics, Muenster University Hospital, 48149 Muenster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4940-6928","authenticated-orcid":false,"given":"Yannik","family":"Hanusrichter","sequence":"additional","affiliation":[{"name":"Department of Tumour Orthopaedics and Revision Arthroplasty, Orthopaedic Hospital Volmarstein, 58300 Wetter, Germany"},{"name":"Center for Musculoskeletal Surgery, University Hospital of Essen, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Periklis","family":"Godolias","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Trauma Surgery, St. Josef Hospital Essen-Werden, 45239 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Wessling","sequence":"additional","affiliation":[{"name":"Department of Tumour Orthopaedics and Revision Arthroplasty, Orthopaedic Hospital Volmarstein, 58300 Wetter, Germany"},{"name":"Center for Musculoskeletal Surgery, University Hospital of Essen, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"609","DOI":"10.3928\/01477447-20060701-01","article-title":"Advances and challenges in diagnosis and management of skeletal metastases","volume":"29","author":"Papagelopoulos","year":"2006","journal-title":"Orthopedics"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"653","DOI":"10.2106\/00004623-198163040-00017","article-title":"The management of acetabular insufficiency secondary to metastatic malignant disease","volume":"63","author":"Harrington","year":"1981","journal-title":"J. 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