{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T18:09:53Z","timestamp":1789236593261,"version":"build-2803163510"},"reference-count":27,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Robotics is commonly used in the rehabilitation of neuro-musculoskeletal injuries and diseases. While in these conditions, robotics has clear benefits, it is unknown whether robotics will also enhance the outcome of cardiac rehabilitation. This systematic review evaluates the use of robotics in cardiac rehabilitation. Methods: A systematic literature search was conducted using PubMed (MEDLINE), CINAHL, AMED, SPORTDiscus, and the Physiotherapy Evidence Database. Longitudinal interventional studies were included if they met specified criteria. Two reviewers independently conducted title, abstract, and full-text screening and data extraction. The quality assessment and risk of bias were conducted according to the PEDRO scale and Cochrane Risk of Bias tool 2, respectively. Results: Four trials were included in this review out of 60 screened studies. The quality of the included studies was good with a low risk of bias. The trials used different robotic systems: Lokomat\u00ae system, Motomed Letto\/Thera Trainer tigo, BEAR, and Myosuit. It was found that interventions that included the use of robotic assistance technologies improved the exercise capacity, VO2 max\/peak, left ventricular ejection fraction, QOL, and physical functioning in people with cardiac diseases. Conclusions: Robotic assistance technologies can be used in cardiac rehabilitation programs. Further studies are needed to confirm the results and determine whether the use of robotics enhances intervention outcomes above standard interventions.<\/jats:p>","DOI":"10.3390\/medicina60071161","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T10:39:26Z","timestamp":1721299166000},"page":"1161","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Application of Robotics in Cardiac Rehabilitation: A Systematic Review"],"prefix":"10.3390","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2185-0859","authenticated-orcid":false,"given":"Aseel","family":"Aburub","sequence":"first","affiliation":[{"name":"Department of Physiotherapy, Applied Science Private University, Amman 11931, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0535-0195","authenticated-orcid":false,"given":"Mohammad Z.","family":"Darabseh","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, School of Rehabilitation Sciences, The University of Jordan, Amman 11942, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6617-6063","authenticated-orcid":false,"given":"Rahaf","family":"Badran","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Faculty of Applied Medical Sciences, Middle East University, Amman 11831, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ala\u2019a M.","family":"Shurrab","sequence":"additional","affiliation":[{"name":"Department of Basic Medical Science, Faculty of Medicine, Al-Balqa Applied University, Al Salt 19117, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anwaar","family":"Amro","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy, Applied Science Private University, Amman 11931, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7399-4841","authenticated-orcid":false,"given":"Hans","family":"Degens","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, Institute of Sport, Manchester Metropolitan University, Manchester M1 5GD, UK"},{"name":"Institute of Sport Science and Innovations, Lithuanian Sports University, LT 221 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (WHO) (2024, June 20). Cardiovascular Diseases (CVDs): Key Facts 2017. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cardiovascular-diseases-(cvds)."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.4258\/hir.2021.27.2.95","article-title":"Future and development direction of digital healthcare","volume":"27","author":"Kim","year":"2021","journal-title":"Healthc. Inform. Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"38","DOI":"10.21037\/mhealth.2017.08.07","article-title":"Digital health is a cultural transformation of traditional healthcare","volume":"3","author":"Drobni","year":"2017","journal-title":"Mhealth"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Jat, A.S., and Gr\u00f8nli, T.-M. (2022, January 27\u201330). Smart watch for smart health monitoring: A literature review. Proceedings of the International Work-Conference on Bioinformatics and Biomedical Engineering, Gran Canaria, Spain.","DOI":"10.1007\/978-3-031-07704-3_21"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Aburub, A., Darabseh, M.Z., Badran, R., Eilayyan, O., Shurrab, A.a.M., and Degens, H. (2024). The Effects of Digital Health Interventions for Pulmonary Rehabilitation in People with COPD: A Systematic Review of Randomized Controlled Trials. Medicina, 60.","DOI":"10.3390\/medicina60060963"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s12265-015-9629-1","article-title":"Digital health intervention as an adjunct to cardiac rehabilitation reduces cardiovascular risk factors and rehospitalizations","volume":"8","author":"Widmer","year":"2015","journal-title":"J. Cardiovasc. Transl. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1177\/1357633X14562732","article-title":"A review of telerehabilitation for cardiac patients","volume":"21","author":"Frederix","year":"2015","journal-title":"J. Telemed. Telecare"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/23288604.2019.1583040","article-title":"Digital technology and the future of health systems","volume":"5","author":"Mitchell","year":"2019","journal-title":"Health Syst. Reform."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Oldenburg, J., Chase, D., Christensen, K.T., and Tritle, B. (2020). Engage!: Transforming Healthcare through Digital Patient Engagement, CRC Press.","DOI":"10.4324\/9780367648015"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.physio.2020.08.001","article-title":"Digital interventions for promoting exercise adherence in chronic musculoskeletal pain: A systematic review and meta-analysis","volume":"111","author":"Bunting","year":"2021","journal-title":"Physiotherapy"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"C\u00e9spedes, N., Irfan, B., Senft, E., Cifuentes, C.A., Gutierrez, L.F., Rincon-Roncancio, M., Belpaeme, T., and M\u00fanera, M. (2021). A socially assistive robot for long-term cardiac rehabilitation in the real world. Front. Neurorobotics, 15.","DOI":"10.3389\/fnbot.2021.633248"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/MRR.0b013e32836195d1","article-title":"Robotics in rehabilitation: Successes and expectations","volume":"36","author":"Fazekas","year":"2013","journal-title":"Int. J. Rehabil. Res."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Guo, Y., Gu, X., and Yang, G.-Z. (2021). Human\u2013Robot Interaction for Rehabilitation Robotics, Springer.","DOI":"10.1007\/978-3-030-65896-0_23"},{"key":"ref_14","unstructured":"Erol, D., Mallapragada, V., Sarkar, N., Uswatte, G., and Taub, E. (2006, January 20\u201322). Autonomously adapting robotic assistance for rehabilitation therapy. Proceedings of the First IEEE\/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics, Pisa, Italy."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1080\/09638288.2019.1631892","article-title":"Virtual reality and video games in cardiac rehabilitation programs. A systematic review","volume":"43","year":"2021","journal-title":"Disabil. Rehabil."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"174","DOI":"10.5853\/jos.2013.15.3.174","article-title":"Robot-assisted therapy in stroke rehabilitation","volume":"15","author":"Chang","year":"2013","journal-title":"J. Stroke"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s13311-018-0642-3","article-title":"Robotic rehabilitation and spinal cord injury: A narrative review","volume":"15","author":"Mekki","year":"2018","journal-title":"Neurotherapeutics"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Payedimarri, A.B., Ratti, M., Rescinito, R., Vanhaecht, K., and Panella, M. (2022). Effectiveness of platform-based robot-assisted rehabilitation for musculoskeletal or neurologic injuries: A systematic review. Bioengineering, 9.","DOI":"10.3390\/bioengineering9040129"},{"key":"ref_19","unstructured":"EM MEDICA (2021). Effects of robot-assisted gait training on postural instability in Parkinson\u2019s disease: A systematic review. Eur. J. Phys. Rehabil. Med., 57, 472\u2013477."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.jclinepi.2009.10.005","article-title":"There was evidence of convergent and construct validity of Physiotherapy Evidence Database quality scale for physiotherapy trials","volume":"63","author":"Macedo","year":"2010","journal-title":"J. Clin. Epidemiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jclinepi.2017.03.002","article-title":"The PEDro scale had acceptably high convergent validity, construct validity, and interrater reliability in evaluating methodological quality of pharmaceutical trials","volume":"86","author":"Yamato","year":"2017","journal-title":"J. Clin. Epidemiol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.2522\/ptj.20110274","article-title":"Extended exercise rehabilitation after hip fracture improves patients\u2019 physical function: A systematic review and meta-analysis","volume":"92","author":"Auais","year":"2012","journal-title":"Phys. Ther."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Hashimoto, K., Hirashiki, A., Ozaki, K., Kawamura, K., Sugioka, J., Tanioku, S., Sato, K., Ueda, I., Itoh, N., and Nomoto, K. (2022). Benefits of a Balance Exercise Assist Robot in the Cardiac Rehabilitation of Older Adults with Cardiovascular Disease: A Preliminary Study. J. Cardiovasc. Dev. Dis., 9.","DOI":"10.3390\/jcdd9060191"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1111\/jocs.12576","article-title":"Robot-Assisted Training Early after Cardiac Surgery","volume":"30","author":"Schoenrath","year":"2015","journal-title":"J. Card. Surg."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Bart\u00edk, P., Vostr\u00fd, M., Hud\u00e1kov\u00e1, Z., \u0160ag\u00e1t, P., Les\u0148\u00e1kov\u00e1, A., and Duk\u00e1t, A. (2022). The Effect of Early Applied Robot-Assisted Physiotherapy on Functional Independence Measure Score in Post-Myocardial Infarction Patients. Healthcare, 10.","DOI":"10.3390\/healthcare10050937"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1002\/ehf2.13903","article-title":"Movement therapy in advanced heart failure assisted by a lightweight wearable robot: A feasibility pilot study","volume":"9","author":"Just","year":"2022","journal-title":"ESC Heart Fail."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/7\/1161\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:18:59Z","timestamp":1760109539000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/7\/1161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,18]]},"references-count":27,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["medicina60071161"],"URL":"https:\/\/doi.org\/10.3390\/medicina60071161","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,18]]}}}