{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:09:05Z","timestamp":1793830145425,"version":"4.6.1"},"reference-count":38,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T00:00:00Z","timestamp":1721865600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background: Narrow-band imaging is an advanced endoscopic technology used to detect changes on the laryngeal tissue surface, employing a comparative approach alongside white-light endoscopy to facilitate histopathological examination. Objective: This study aimed to assess the utility and advantages of NBI (narrow-band imaging) in identifying malignant laryngeal lesions through a comparative analysis with histopathological examination. Methods: We conducted a systematic literature review, utilizing databases such as PubMed, the CNKI database, and Embase for our research. Results: We analyzed the articles by reviewing their titles and abstracts, selecting those we considered relevant based on determined criteria; in the final phase, we examined the relevant studies according to the specific eligibility criteria. Conclusions: Narrow-band imaging is an advanced endoscopic technology that demonstrates its efficacy as a tool for diagnosing malignant laryngeal lesions and comparing them to premalignant lesions. The European Society of Laryngology has implemented a standardized classification system for laryngeal lesions to enhance data correlation and organization.<\/jats:p>","DOI":"10.3390\/medicina60081205","type":"journal-article","created":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T13:10:28Z","timestamp":1721913028000},"page":"1205","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Systematic Review Evaluating the Diagnostic Efficacy of Narrow-Band Imaging for Laryngeal Cancer Detection"],"prefix":"10.3390","volume":"60","author":[{"given":"Ileana Alexandra","family":"Sanda","sequence":"first","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy, General Medicine, 050474 Bucharest, Romania"},{"name":"ENT Institute of Phonoaudiology and Functional Surgery \u201cProf. Dr. D. Hociota\u201d, 050751 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Razvan","family":"Hainarosie","sequence":"additional","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy, General Medicine, 050474 Bucharest, Romania"},{"name":"ENT Institute of Phonoaudiology and Functional Surgery \u201cProf. Dr. D. Hociota\u201d, 050751 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina Gabriela","family":"Ionita","sequence":"additional","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy, General Medicine, 050474 Bucharest, Romania"},{"name":"ENT Institute of Phonoaudiology and Functional Surgery \u201cProf. Dr. D. Hociota\u201d, 050751 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"Voiosu","sequence":"additional","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy, General Medicine, 050474 Bucharest, Romania"},{"name":"ENT Institute of Phonoaudiology and Functional Surgery \u201cProf. Dr. D. Hociota\u201d, 050751 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius Razvan","family":"Ristea","sequence":"additional","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy, General Medicine, 050474 Bucharest, Romania"},{"name":"Bucharest Emergency University Hospital, 050098 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6269-9126","authenticated-orcid":false,"given":"Adina","family":"Zamfir Chiru Anton","sequence":"additional","affiliation":[{"name":"\u201cGrigore Alexandrescu\u201d Emergency Children Hospital, 011732 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.21037\/jtd.2016.11.61","article-title":"White light, autofluorescence and narrow-band imaging bronchoscopy for diagnosing airway pre-cancerous and early cancer lesions: A systematic review and meta-analysis","volume":"8","author":"Zhang","year":"2016","journal-title":"J. Thorac. Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"438","DOI":"10.6061\/clinics\/2017(07)09","article-title":"The diagnostic value of narrow-band imaging for early and invasive lung cancer: A meta-analysis","volume":"72","author":"Zhu","year":"2017","journal-title":"Clinics"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1002\/ijc.32823","article-title":"Tobacco smoking, chewing habits, alcohol drinking, and the risk of head and neck cancer in Nepal","volume":"147","author":"Chang","year":"2020","journal-title":"Int. J. Cancer"},{"key":"ref_4","first-page":"2248","article-title":"Laryngeal Cancer: Epidemiology, Etiology, and Prevention: A Narrative Review","volume":"52","author":"Igissin","year":"2023","journal-title":"Iran. J. Public Health"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1097\/MOO.0b013e32835908ac","article-title":"Narrow band imaging in endoscopic evaluation of the larynx","volume":"20","author":"Piazza","year":"2012","journal-title":"Curr. Opin. Otolaryngol. Head Neck Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.21037\/qims-22-728","article-title":"A narrative review: Narrrow band imaging endoscopic classifications","volume":"13","author":"Yang","year":"2023","journal-title":"Quant. Imaging Med. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.bjorl.2019.07.009","article-title":"Correlation of narrow band imaging vascular patterns with immunohistological microvessel density in vocal fold lesions","volume":"87","author":"Rzepakowska","year":"2021","journal-title":"Braz. J. Otorhinolaryngol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s12070-023-04183-5","article-title":"Contact Endoscopic Surface Vascular and Epithelial Morphology in Leukoplakia and Carcinoma of the Vocal Cords","volume":"76","author":"Pavlidis","year":"2024","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1017\/S0022215110002033","article-title":"Endoscopic diagnosis of laryngeal cancer and precancerous lesions by narrow band imaging","volume":"125","author":"Ni","year":"2011","journal-title":"J. Laryngol. Otol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1002\/lsm.23143","article-title":"Efficacy of transnasal flexible videoendoscopy with narrow band imaging for follow-up of patients after transoral laser cordectomy","volume":"52","author":"Lukes","year":"2020","journal-title":"Lasers Surg. Med."},{"key":"ref_11","unstructured":"(2024, May 03). European Society of Laryngology. Available online: https:\/\/www.elsoc.org\/."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s11912-015-0498-1","article-title":"The Role of Narrow Band Imaging in Head and Neck Cancers","volume":"18","author":"Ni","year":"2016","journal-title":"Curr. Oncol. Rep."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.critrevonc.2016.07.004","article-title":"Laryngeal preneoplastic lesions and cancer: Challenging diagnosis. Qualitative literature review and meta-analysis","volume":"106","author":"Mannelli","year":"2016","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Tiu, V.E., Popescu, B.O., Enache, I.I., Tiu, C., Terecoasa, E., and Panea, C.A. (2022). Serum and CSF Biomarkers Predict Active Early Cognitive Decline Rather Than Established Cognitive Impairment at the Moment of RRMS Diagnosis. Diagnostics, 12.","DOI":"10.3390\/diagnostics12112571"},{"key":"ref_15","first-page":"900","article-title":"Application of narrow band imaging in the detection of premalignant and malignant lesions of the larynx","volume":"52","author":"Wu","year":"2017","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2635","DOI":"10.1002\/hed.26186","article-title":"Use of narrowband imaging for the diagnosis and screening of laryngeal cancer: A systematic review and meta-analysis","volume":"42","author":"Kim","year":"2020","journal-title":"Head Neck"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4103\/ijc.IJC_590_17","article-title":"Role of narrow band imaging in the diagnosis of laryngeal lesions: Pilot study from India","volume":"55","author":"Sakthivel","year":"2018","journal-title":"Indian J. Cancer"},{"key":"ref_18","first-page":"428","article-title":"Application of narrow band imaging in laryngeal tumor","volume":"31","author":"Yue","year":"2017","journal-title":"Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"ref_19","first-page":"2078","article-title":"The value of target biopsy using narrow band imaging endoscopy for diagnosis of laryngeal carcinoma","volume":"29","author":"Yang","year":"2015","journal-title":"Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"ref_20","first-page":"665","article-title":"Role of narrow band imaging in the detection of malignant lesions of the oropharynx and the laryngopharynx","volume":"32","author":"Wu","year":"2018","journal-title":"Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"ref_21","first-page":"627","article-title":"Application of narrow-band imaging endoscopy in laryngeal malignant lesion biopsy","volume":"49","author":"Yang","year":"2014","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1177\/0145561320925327","article-title":"Diagnostic Value and Pathological Correlation of Narrow Band Imaging Classification in Laryngeal Lesions","volume":"100","author":"Lin","year":"2021","journal-title":"Ear Nose Throat J."},{"key":"ref_23","first-page":"22","article-title":"Diagnostic Value of Narrow Band Imaging in Visualization of Pathological Lesions in Larynx and Hypopharynx","volume":"64","author":"Laco","year":"2021","journal-title":"Acta Medica"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"18","DOI":"10.5604\/01.3001.0013.3401","article-title":"Clinical experience of narrow band imaging (NBI) usage in diagnosis of laryngeal lesions","volume":"73","author":"Popek","year":"2019","journal-title":"Otolaryngol. Pol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/hed.23838","article-title":"Value of narrow band imaging in the early diagnosis of laryngeal cancer","volume":"38","author":"Kraft","year":"2016","journal-title":"Head Neck"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/coa.12728","article-title":"Narrow band imaging as screening test for early detection of laryngeal cancer: A prospective study","volume":"42","author":"Meccariello","year":"2017","journal-title":"Clin. Otolaryngol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"5127","DOI":"10.1007\/s12070-021-02945-7","article-title":"Role of Narrow Band Imaging in Laryngeal Lesions: A Prospective Study from Southern India","volume":"74","author":"Sargunaraj","year":"2022","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"107","DOI":"10.32725\/jab.2023.015","article-title":"The importance of preoperative and perioperative Narrow Band Imaging endoscopy in the diagnosis of pre-tumor and tumor lesions of the larynx","volume":"21","author":"Filipovsky","year":"2023","journal-title":"J. Appl. Biomed."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Galli, J., Settimi, S., Mele, D.A., Salvati, A., Schiavi, E., Parrilla, C., and Paludetti, G. (2021). Role of Narrow Band Imaging Technology in the Diagnosis and Follow up of Laryngeal Lesions: Assessment of Diagnostic Accuracy and Reliability in a Large Patient Cohort. J. Clin. Med., 10.","DOI":"10.3390\/jcm10061224"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s00405-008-0835-1","article-title":"The value of narrow band imaging for early detection of laryngeal cancer","volume":"266","author":"Watanabe","year":"2009","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/hed.23582","article-title":"Effectiveness of narrow band imaging in the detection of premalignant and malignant lesions of the larynx: Validation of a new endoscopic clinical classification","volume":"37","author":"Bertino","year":"2015","journal-title":"Head Neck"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1080\/00016489.2017.1324216","article-title":"The usefulness of narrow-band imaging for the diagnosis and treatment of vocal fold leukoplakia","volume":"137","author":"Huang","year":"2017","journal-title":"Acta Otolaryngol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/coa.12654","article-title":"The clinical diagnostic value of target biopsy using narrow-band imaging endoscopy and accurate laryngeal carcinoma pathologic specimen acquisition","volume":"42","author":"Yang","year":"2017","journal-title":"Clin. Otolaryngol."},{"key":"ref_34","first-page":"143","article-title":"Application of narrow band imaging endoscopy in the diagnosis of laryngeal cancer","volume":"45","author":"Ni","year":"2010","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1002\/lary.26263","article-title":"Does narrow band imaging improve preoperative detection of glottic malignancy? A matched comparison study","volume":"127","author":"Lahav","year":"2017","journal-title":"Laryngoscope"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00405-016-4244-6","article-title":"The role of narrow-band imaging (NBI) endoscopy in optical biopsy of vocal cord leukoplakia","volume":"274","year":"2017","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00405-018-5256-1","article-title":"Flexible transnasal endoscopy with white light or narrow band imaging for the diagnosis of laryngeal malignancy: Diagnostic value, observer variability and influence of previous laryngeal surgery","volume":"276","author":"Davaris","year":"2019","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1007\/s00405-020-05864-5","article-title":"The diagnostic value of perpendicular vascular patterns of vocal cords defined by narrow-band imaging","volume":"277","author":"Gale","year":"2020","journal-title":"Eur. Arch. Otorhinolaryngol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/8\/1205\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:23:26Z","timestamp":1760109806000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/8\/1205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,25]]},"references-count":38,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["medicina60081205"],"URL":"https:\/\/doi.org\/10.3390\/medicina60081205","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,25]]}}}