{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:02:02Z","timestamp":1773100922431,"version":"3.50.1"},"reference-count":19,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T00:00:00Z","timestamp":1729555200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2021R1I1A3048089"],"award-info":[{"award-number":["NRF-2021R1I1A3048089"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background\/Objectives: Anatomical variations in the biceps brachii muscle (BBM) are extremely frequent, leading to developmental and clinical implications. We studied the topography of the BBM and analyzed its correlations with other structures in the brachial region. Methods: A total of 103 cadaveric upper extremities were dissected. The length of the upper extremities was utilized as a reference line. The origin and insertion of the BBM, the coracobrachialis muscle (CBM), and the related neurovascular system were evaluated. Results: Each variable was calculated as a percentile and compared according to the presence of the considered variation; in particular, a supernumerary head of the BBM was found in 12\/103 (11.65%) of upper extremities and was associated with a longer upper limb (506.25 \u00b1 32.55 mm vs. 484.27 \u00b1 30.41 mm, p = 0.022). When the variables were standardized by the length of the upper limb, the accessory head of the BBM was associated with the distal insertion point of the CBM (28.18 \u00b1 3.54% vs. 30.59 \u00b1 2.94%, p = 0.011) and BBM length (55.11 \u00b1 2.17% vs. 58.18 \u00b1 3.72%, p = 0.006). Other variables did not present significant differences with respect to the presence of the supernumerary head of the BBM. Conclusions: BBM variations may affect the topography of other structures, such as the length of the upper extremities, insertion of the CBM, and length of the BBM. Further studies are required to elucidate its clinical implications.<\/jats:p>","DOI":"10.3390\/medicina60111726","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T06:11:25Z","timestamp":1729577485000},"page":"1726","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Supernumerary Head of the Biceps Brachii Muscle Influences the Topography of the Coracobrachialis and Biceps Brachii Muscles"],"prefix":"10.3390","volume":"60","author":[{"given":"Yu-Ran","family":"Heo","sequence":"first","affiliation":[{"name":"Department of Anatomy, Keimyung University School of Medicine, Daegu 42601, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3631-3028","authenticated-orcid":false,"given":"Hyunsu","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Physiology, Pusan National University School of Medicine, Yangsan 50612, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si-Wook","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Keimyung University Dongsan Hospital, Daegu 42601, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8728-512X","authenticated-orcid":false,"given":"Beom-Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Keimyung University Dongsan Hospital, Daegu 42601, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6701-8481","authenticated-orcid":false,"given":"Hong-Tae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anatomy, School of Medicine, Catholic University of Daegu, Daegu 42472, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5562-0720","authenticated-orcid":false,"given":"Jae-Ho","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Keimyung University School of Medicine, Daegu 42601, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.14740\/jocmr2901w","article-title":"Actions of the Biceps Brachii at the Shoulder: A Review","volume":"9","author":"Landin","year":"2017","journal-title":"J. Clin. Med. Res."},{"key":"ref_2","first-page":"101","article-title":"High incidence of the third head of biceps brachii in south african populations","volume":"182","author":"Asvat","year":"1993","journal-title":"J. Anat."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/ca.20100","article-title":"Three-headed biceps brachii muscle associated with duplicated musculocutaneous nerve","volume":"18","year":"2005","journal-title":"Clin. Anat."},{"key":"ref_4","first-page":"116","article-title":"An anatomical study on the three-headed biceps brachii in human foetuses, and clinical relevance","volume":"70","author":"Kervancioglu","year":"2011","journal-title":"Folia Morphol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"266","DOI":"10.4103\/ijabmr.IJABMR_339_16","article-title":"Bilateral three-headed biceps brachii muscle and its clinical implications","volume":"7","author":"Saluja","year":"2017","journal-title":"Int. J. Appl. Basic Med. Res."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.11637\/kjpa.1992.5.2.139","article-title":"The relation of the musculocutaneous nerve to the coracobrachialis muscle in Korean adults","volume":"5","author":"Kang","year":"1992","journal-title":"Korean J. Phys. Anthropol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"327","DOI":"10.2478\/folmed-2018-0080","article-title":"Anatomical variations of the musculocutaneous and median nerves: A case report","volume":"61","author":"Darvishi","year":"2019","journal-title":"Folia. Med."},{"key":"ref_8","unstructured":"Tucker, W.D., Arora, Y., and Mahajan, K. (2021). Anatomy, Blood Vessels, StatPearls."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s00276-005-0326-7","article-title":"Morphometric study of the nerves entering into the coracobrachialis muscle","volume":"27","author":"Ozturk","year":"2005","journal-title":"Surg. Radiol. Anat."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"359","DOI":"10.5603\/FM.a2019.0075","article-title":"Long head of biceps brachii tendon and transverse humeral ligament morphometry and their associated pathology","volume":"79","author":"Khan","year":"2020","journal-title":"Folia Morphol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Szewczyk, B., Sanudo, J.R., Podg\u00f3rski, M., Zielinska, N., Pires, M.B., Aragon\u00e9s, P., and Olewnik, \u0141. (2022). A Proposal for a New Classification of the Supernumerary Heads of the Biceps Brachii Muscle. Biomed Res Int., 2022.","DOI":"10.1155\/2022\/1510363"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1097\/PHM.0000000000001057","article-title":"Trifid median nerve: A rare variant in a patient with carpal tunnel syndrome","volume":"98","author":"Cai","year":"2019","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_13","first-page":"45","article-title":"Fusion between the median and musculocutaneous nerve: A case study","volume":"59","author":"Clarke","year":"2019","journal-title":"Folia. Med. Cracov."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/ca.20828","article-title":"Classifying musculocutaneous nerve variations","volume":"22","author":"Ingolotti","year":"2009","journal-title":"Clin. Anat."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s12565-010-0094-2","article-title":"The superficial brachial artery passing superficially to the pectoral ansa, the highest superficial brachial artery (arteria brachialis superficialis suprema)","volume":"86","author":"Honma","year":"2011","journal-title":"Anat. Sci. Int."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00276-017-1919-7","article-title":"Morphology and relationships of the biceps brachii and brachialis with the musculocutaneous nerve","volume":"40","author":"Yamamoto","year":"2018","journal-title":"Surg. Radiol. Anat."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Tubbs, R.S., Shoja, M.M., and Loukas, M. (2016). Bergman\u2019s Comprehensive Encyclopedia of Human Anatomic Variation, John Wiley & Sons.","DOI":"10.1002\/9781118430309"},{"key":"ref_18","first-page":"100282","article-title":"The third head of the biceps brachii muscle exhibiting variable shape presentation: Prevalence, variability and clinical considerations","volume":"34","author":"Manjatika","year":"2024","journal-title":"Transl. Res. Anat."},{"key":"ref_19","first-page":"100289","article-title":"Structural and functional analysis of bilateral five-headed biceps brachii muscles with clinical insights","volume":"35","author":"Snow","year":"2024","journal-title":"Transl. Res. Anat."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/11\/1726\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:17:35Z","timestamp":1760113055000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/11\/1726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,22]]},"references-count":19,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["medicina60111726"],"URL":"https:\/\/doi.org\/10.3390\/medicina60111726","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,22]]}}}