{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:26:56Z","timestamp":1793395616952,"version":"4.5.0"},"reference-count":29,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Oradea, Oradea, Romania"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: This study explores the impact of hormonal fluctuations during pregnancy and lifestyle factors on stomatognathic system (SS) health. The aim is to determine how pregnancy-related hormonal changes and oral hygiene behaviors affect the onset of stomatognathic issues, such as gingival inflammation (GI) and dental erosion (DE). Materials and Methods: A prospective, observational study was conducted with 100 pregnant women, divided into two groups: Group A (60 women with significant stomatognathic alterations) and Group B (40 women without such alterations). Multiple regression analysis was used to evaluate the influence of hormonal levels, oral hygiene habits, and vomiting episodes on stomatognathic health. Results: Age and socioeconomic status showed no significant association with stomatognathic health (p &gt; 0.05). In contrast, elevated levels of estrogen (p = 0.001) and progesterone (p = 0.003) were significantly linked to the severity of stomatognathic changes. Oral hygiene habits also had a statistically significant impact (p = 0.02), while vomiting frequency was not an important factor (p &gt; 0.05). Conclusions: Hormonal changes during pregnancy, particularly increased estrogen and progesterone levels, are key predictors of stomatognathic health. These findings suggest that while oral hygiene is important, hormonal fluctuations play a dominant role in influencing stomatognathic system (SS) health during pregnancy.<\/jats:p>","DOI":"10.3390\/medicina60111773","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T10:49:52Z","timestamp":1730285392000},"page":"1773","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Impact of Hormones and Lifestyle on Oral Health During Pregnancy: A Prospective Observational Regression-Based Study"],"prefix":"10.3390","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7701-2307","authenticated-orcid":false,"given":"Liliana","family":"Sachelarie","sequence":"first","affiliation":[{"name":"Preclinics Department, Faculty of Medicine, Apollonia University, 700511 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ait el haj","family":"Iman","sequence":"additional","affiliation":[{"name":"Preclinics Department, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2747-1411","authenticated-orcid":false,"given":"Murvai Violeta","family":"Romina","sequence":"additional","affiliation":[{"name":"Preclinics Department, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5998-9488","authenticated-orcid":false,"given":"Anca","family":"Huniadi","sequence":"additional","affiliation":[{"name":"Clinics Department, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3803-9405","authenticated-orcid":false,"given":"Loredana Liliana","family":"Hurjui","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1111\/j.1600-051X.2008.01236.x","article-title":"Clinical changes in periodontium during pregnancy and post-partum","volume":"35","author":"Pajukanta","year":"2008","journal-title":"J. Clin. Periodontol."},{"key":"ref_2","unstructured":"World Health Organization (2018). Oral Health."},{"key":"ref_3","first-page":"1009","article-title":"Oral health in pregnancy (guidelines to gynaecologists, general physicians & oral health care providers)","volume":"61","author":"Kandan","year":"2011","journal-title":"JPMA-J. Pak. Med. Assoc."},{"key":"ref_4","first-page":"1139","article-title":"Oral health during pregnancy","volume":"77","author":"Silk","year":"2008","journal-title":"Am. Fam. 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