{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:18:24Z","timestamp":1791922704965,"version":"4.3.4"},"reference-count":40,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007446","name":"King Khalid University","doi-asserted-by":"publisher","award":["1\/105\/45"],"award-info":[{"award-number":["1\/105\/45"]}],"id":[{"id":"10.13039\/501100007446","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and\u00a0Objective: The aim of this study was to evaluate cardiorespiratory fitness (CRF) measures, maximal oxygen consumption (VO2 max), and minute ventilation\/carbon dioxide production (VE\/VCO2 slope and others) among the T2DM population based on glycated haemoglobin (HBA1c). Material and Methods: The present study comprised a cross-sectional design, with two groups, based on HbA1c values (\u22647 and \u22657.1). Laboratory samples were taken to evaluate glycated haemoglobin and fasting blood glucose (FBS). Cardiopulmonary exercise testing was performed to calculate various fitness-related parameters. Data analysis: An independent t-test was used to analyse the outcomes in the two groups. p &lt; 0.05 was considered significant. Linear regression was used to examine the influence of predictor variables on dependent variables. Results: A total of 70 patients agreed to participate in the study, with 19 females and 51 males. The mean (standard deviation) BMI (body mass index) of all participants was 29.7(5.2), the mean (SD) weight was 84.4 (18.9) kg, and the mean height was 167.4 (23) cm. The average age of the individuals was 52 \u00b1 8 years. The independent t-test revealed a significant difference between the two groups in terms of CRF measures. Conclusions: The current research identified the presence of poor glycaemic control and cardiorespiratory fitness measures among the Brazilian population with T2DM. HBA1c, duration of diabetes, age, and BMI can be employed to predict the ventilatory threshold (VT) and VO2 max.<\/jats:p>","DOI":"10.3390\/medicina60111823","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T06:27:39Z","timestamp":1730874459000},"page":"1823","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of Glycated Haemoglobin (HBA1c) on Cardiorespiratory Fitness (CRF) in a Population with Type 2 Diabetes Mellitus (T2DM): A Cross-Sectional Study"],"prefix":"10.3390","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1617-6935","authenticated-orcid":false,"given":"Snehil","family":"Dixit","sequence":"first","affiliation":[{"name":"Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Alfara 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Bassi-Dibai","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Management and Health Care, Ceuma University, S\u00e3o Lu\u00eds 65075-120, MA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almir Vieira","family":"Dibai-Filho","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Physical Education, Federal University of Maranhao, S\u00e3o Lu\u00eds 65080-805, MA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata G.","family":"Mendes","sequence":"additional","affiliation":[{"name":"Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of Sao Carlos, Sao Carlos 13565-905, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7396-5079","authenticated-orcid":false,"given":"Abdulfattah S.","family":"Alqahtani","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11451, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed M.","family":"Alshehri","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5255-4860","authenticated-orcid":false,"given":"Monira I.","family":"Aldhahi","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Batool Abdulelah","family":"Alkhamis","sequence":"additional","affiliation":[{"name":"Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Alfara 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6638-0585","authenticated-orcid":false,"given":"Ravi Shankar","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Alfara 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2876-4227","authenticated-orcid":false,"given":"Jaya Shanker","family":"Tedla","sequence":"additional","affiliation":[{"name":"Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Alfara 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3891-6941","authenticated-orcid":false,"given":"Audrey","family":"Borghi-Silva","sequence":"additional","affiliation":[{"name":"Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of Sao Carlos, Sao Carlos 13565-905, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2337\/dc20-S002","article-title":"Classification and diagnosis of diabetes: Standards of Medical Care in Diabetes-2020","volume":"43","author":"Care","year":"2020","journal-title":"Diabetes Care"},{"key":"ref_2","unstructured":"(2024, June 11). 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