{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:26:14Z","timestamp":1791390374776,"version":"4.3.3"},"reference-count":26,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T00:00:00Z","timestamp":1733097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Extracorporeal cardiopulmonary resuscitation (ECPR) is a complex, life-saving procedure that uses mechanical support for patients with refractory cardiac arrest, representing the pinnacle of extracorporeal membrane oxygenation (ECMO) applications. Effective ECPR requires precise patient selection, rapid mobilization of a multidisciplinary team, and skilled cannulation techniques. Establishing a program necessitates a cohesive ECMO system that promotes interdisciplinary collaboration, which is essential for managing acute cardiogenic shock and severe pulmonary failure. ECPR is suited for selected patients, emphasizing the need to optimize every step of cardiac arrest management\u2014from public education to advanced post-resuscitation care. The flexibility of ECMO teams allows them to manage various emergencies such as cardiogenic shock, massive pulmonary embolism, and severe asthma, showcasing the program\u2019s adaptability. Launching an ECPR program involves addressing logistical, financial, and organizational challenges. This includes gaining administrative approval, assembling a diverse team, and crafting detailed protocols and training regimens. The development process entails organizing teams, refining protocols, and training extensively to ensure operational readiness. A systematic approach to building an ECPR program involves establishing a team, defining patient selection criteria, and evaluating caseloads. Critical elements like patient transport protocols and anticoagulation management are vital for the program\u2019s success. In conclusion, initiating an ECPR program demands thorough planning, collaborative effort across specialties, and ongoing evaluation to improve outcomes in critical cardiac emergencies. This guide offers practical insights to support institutions in navigating the complexities of ECPR program development and maintenance.<\/jats:p>","DOI":"10.3390\/medicina60121979","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T06:58:58Z","timestamp":1733122738000},"page":"1979","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Establishing an Extracorporeal Cardiopulmonary Resuscitation Program"],"prefix":"10.3390","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3878-044X","authenticated-orcid":false,"given":"Pietro","family":"Bertini","sequence":"first","affiliation":[{"name":"Department of Anesthesia and Intensive Care Medicine, Casa di Cura Privata San Rossore, 56122 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0645-2000","authenticated-orcid":false,"given":"Fabio","family":"Sangalli","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, ASST Valtellina e Alto Lario, University of Milano-Bicocca, 23020 Sondrio, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Meani","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, 6229 HX Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8100-3304","authenticated-orcid":false,"given":"Alberto","family":"Marabotti","sequence":"additional","affiliation":[{"name":"Intensive Care Unit and Regional, ECMO Referral Centre, Azienda Ospedaliero, Universitaria Careggi, 50134 Florence, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Rubino","sequence":"additional","affiliation":[{"name":"Royal Papworth Hospital NHS Foundation Trust, Cambridge CB2 0AY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabino","family":"Scolletta","sequence":"additional","affiliation":[{"name":"Department of Medical Science, Surgery and Neurosciences, Trauma Anesthesia and Intensive Care Unit, University Hospital of Siena, 53100 Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Ajello","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anesthesia, University of Tor Vergata, 00133 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6724-2122","authenticated-orcid":false,"given":"Tommaso","family":"Aloisio","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Anesthesia and Intensive Care Unit (ICU), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Donato, 20097 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7909-6399","authenticated-orcid":false,"given":"Massimo","family":"Baiocchi","sequence":"additional","affiliation":[{"name":"Cardio-Thoracic and Vascular Anesthesia and Intensive Care Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40126 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5186-1976","authenticated-orcid":false,"given":"Fabrizio","family":"Monaco","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4915-3572","authenticated-orcid":false,"given":"Marco","family":"Ranucci","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Anesthesia and Intensive Care Unit (ICU), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Donato, 20097 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4213-9153","authenticated-orcid":false,"given":"Cristina","family":"Santonocito","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria Policlinico-San Marco, Site \u201cPoliclinico G. Rodolico\u201d, 95123 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3320-9228","authenticated-orcid":false,"given":"Simona","family":"Silvetti","sequence":"additional","affiliation":[{"name":"Department of Cardiac Anesthesia and Intensive Care, Ospedale Policlinico San Martino IRCCS, IRCCS Cardiovascular Network, 16132 Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5144-0776","authenticated-orcid":false,"given":"Filippo","family":"Sanfilippo","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care, University Hospital Policlinico G. 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