{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:21:35Z","timestamp":1793395295624,"version":"4.5.0"},"reference-count":73,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T00:00:00Z","timestamp":1734307200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Autonomic nervous system (ANS) disorders are responsible for primary dysmenorrhea and are closely linked to the spine. This study aims to evaluate the effects of sacroiliac joint manipulation on the ANS and lower abdominal pain in women with primary dysmenorrhea and proposes an alternative treatment method. Materials and Methods: A total of 40 participants were randomly assigned; however, 35 participants remained in the final analysis after 5 dropped out; they were assigned to either the sacroiliac joint manipulation group (n = 18) or the superficial heat therapy group (n = 17). Assessments included heart rate variability (HRV), visual analogue scale (VAS) scores for lower abdominal pain, the pressure pain threshold (PPT) of the sacroiliac joint, and the Moos Menstrual Distress Questionnaire (MMDQ) at baseline and after 4 weeks. Only the VAS and MMDQ scores were reassessed after 8 weeks to evaluate the sustained effects of the treatment. Results: Changes in HRV showed improvements in ANS balance only in the sacroiliac joint manipulation group (p &lt; 0.05). It was found to be more effective than superficial heat therapy (p &lt; 0.05). A significant decrease in lower abdominal pain following the intervention was observed in both groups (p &lt; 0.05), along with the sustained effects of the treatment (p &lt; 0.05). The MMDQ scores decreased after sacroiliac joint manipulation (p &lt; 0.05), with greater improvements compared to the superficial heat therapy (p &lt; 0.05). Conclusions: Sacroiliac joint manipulation positively affects ANS balance and is effective in alleviating lower abdominal pain and menstruation-related symptoms, with sustained effects observed over time. Therefore, sacroiliac joint manipulation can be an effective alternative treatment for women with primary dysmenorrhea.<\/jats:p>","DOI":"10.3390\/medicina60122068","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T06:48:39Z","timestamp":1734331719000},"page":"2068","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effects of Sacroiliac Joint Manipulation on Autonomic Nervous System and Lower Abdominal Pain in Women with Primary Dysmenorrhoea: A Randomized Controlled Trial"],"prefix":"10.3390","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5306-5981","authenticated-orcid":false,"given":"Sungeon","family":"Park","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Graduate School, Sahmyook University, 815, Hwarang-ro, Seoul 01795, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6538-3872","authenticated-orcid":false,"given":"Hyunjoong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Senior Exercise Prescription, Gwangju Health University, Bungmun-daero 419 beon-gil, Gwangju 62287, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1255-7792","authenticated-orcid":false,"given":"Jihye","family":"Jung","sequence":"additional","affiliation":[{"name":"Institute of SMART Rehabilitation, Sahmyook University, 815, Hwarang-ro, Seoul 01795, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0413-0510","authenticated-orcid":false,"given":"Seungwon","family":"Lee","sequence":"additional","affiliation":[{"name":"Institute of SMART Rehabilitation, Sahmyook University, 815, Hwarang-ro, Seoul 01795, Republic of Korea"},{"name":"Department of Physical Therapy, Sahmyook University, 815, Hwarang-ro, Seoul 01795, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ctim.2011.06.004","article-title":"A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of a far infrared-emitting sericite belt in patients with primary dysmenorrhea","volume":"19","author":"Lee","year":"2011","journal-title":"Complement. Ther. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1097\/01.AOG.0000230214.26638.0c","article-title":"Primary dysmenorrhea: Advances in pathogenesis and management","volume":"108","author":"Dawood","year":"2006","journal-title":"Gynaecol. Obstet."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1007\/s00404-008-0750-0","article-title":"Prevalence of primary dysmenorrhea in young adult female university students","volume":"279","author":"Polat","year":"2009","journal-title":"Arch. Gynecol. Obstet."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1111\/j.1526-4637.2010.00949.x","article-title":"A comparative study on the immediate effects of electroacupuncture at Sanyinjiao (SP6), Xuanzhong (GB39) and a non-meridian point, on menstrual pain and uterine arterial blood flow, in primary dysmenorrhea patients","volume":"11","author":"Ma","year":"2010","journal-title":"Pain. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1136\/bmj.332.7550.1134","article-title":"Diagnosis and management of dysmenorrhoea","volume":"332","author":"Proctor","year":"2006","journal-title":"Bmj"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.enfcli.2019.07.016","article-title":"Prostaglandin level of primary dysmenorrhea pain sufferers","volume":"30","author":"Fajrin","year":"2020","journal-title":"Enferm. Clin."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.5124\/jkma.2020.63.3.171","article-title":"A comprehensive review and the pharmacologic management of primary dysmenorrhea","volume":"63","author":"Lee","year":"2020","journal-title":"J. Korean Am. Med. Assoc."},{"key":"ref_8","first-page":"CD002119","article-title":"Spinal manipulation for primary and secondary dysmenorrhoea","volume":"3","author":"Proctor","year":"2001","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_9","first-page":"164","article-title":"Analysis on the heart rate variability of dysmenorrhoea patients","volume":"20","author":"Lee","year":"2007","journal-title":"J. Orien. OBGY"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/01674820500490218","article-title":"Autonomic nervous system activity in the late luteal phase of eumenorrheic women with premenstrual symptomatology","volume":"27","author":"Matsumoto","year":"2006","journal-title":"J. Psychosom. Obstet. Gynaecol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"601","DOI":"10.2114\/jpa.24.601","article-title":"Specific physiological responses in women with severe primary dysmenorrhea during the menstrual cycle","volume":"24","author":"Park","year":"2005","journal-title":"J. Physiol. Anthropol. Appl. Human. Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jpsychores.2008.04.008","article-title":"Reduced parasympathetic activity during sleep in the symptomatic phase of severe premenstrual syndrome","volume":"65","author":"Baker","year":"2008","journal-title":"J. Psychosom. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1751-0759-1-24","article-title":"Altered autonomic nervous system activity as a potential etiological factor of premenstrual syndrome and premenstrual dysphoric disorder","volume":"1","author":"Matsumoto","year":"2007","journal-title":"Biopsychosoc. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1080\/00016340600753117","article-title":"Surgical interruption of pelvic nerve pathways in dysmenorrhea: A systematic review of effectiveness","volume":"86","author":"Latthe","year":"2007","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jpag.2013.11.003","article-title":"The effects of local low-dose heat application on dysmenorrhea","volume":"27","author":"Potur","year":"2014","journal-title":"J. Pediatr. Adolesc. Gynecol."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Bernardo-Filho, M. (2021). The influence of sagittal plane spine alignment on neurophysiology and sensorimotor control measures: Optimization of function through structural correction. Therapy Approaches in Neurological Disorders, IntechOpen. Online First.","DOI":"10.5772\/intechopen.91533"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0304-3959(03)00320-8","article-title":"Joint manipulation reduces hyperalgesia by activation of monoamine receptors but not opioid or GABA receptors in the spinal cord","volume":"106","author":"Skyba","year":"2003","journal-title":"Pain"},{"key":"ref_18","first-page":"873","article-title":"Uterosacral ligament: Description of anatomic relationships to optimize surgical safety","volume":"97","author":"Buller","year":"2001","journal-title":"Obstet. Gynecol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00276-006-0171-3","article-title":"The female inferior hypogastric (= pelvic) plexus: Anatomical and radiological description of the plexus and its afferences\u2014Applications to pelvic surgery","volume":"29","author":"Mauroy","year":"2007","journal-title":"Surg. Radiol. Anat."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1002\/ar.1090720306","article-title":"The anatomy and development of the sacro-iliac joint in man","volume":"72","author":"Schunke","year":"1938","journal-title":"Anat. Rec."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/ptj\/70.4.250","article-title":"Anterior dysfunction of the sacroiliac joint as a major factor in the etiology of idiopathic low back pain syndrome","volume":"70","author":"DonTigny","year":"1990","journal-title":"Phys. Ther."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"e92","DOI":"10.7556\/jaoa.2018.139","article-title":"An osteopathic approach to diagnosis and management of sacroiliac joint dysfunction","volume":"118","author":"Glover","year":"2018","journal-title":"J. Osteopath. Med."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Wang, J., He, X., Zhu, C., Ding, H., Feng, G., Yang, X., Liu, L., and Song, Y. (2023). The relationship between spino-pelvic alignment and primary dysmenorrhea. Front. Surg., 10.","DOI":"10.3389\/fsurg.2023.1125520"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"252","DOI":"10.14474\/ptrs.2020.9.4.252","article-title":"The effect of sacroiliac joint manual therapy on heart rate variability in women with primary dysmenorrhea","volume":"9","author":"Park","year":"2020","journal-title":"Phys. Ther. Rehabil. Sci."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"L\u00f3pez-Liria, R., Torres-\u00c1lamo, L., Vega-Ram\u00edrez, F.A., Garc\u00eda-Luengo, A.V., Aguilar-Parra, J.M., Trigueros-Ramos, R., and Rocamora-P\u00e9rez, P. (2021). Efficacy of physiotherapy treatment in primary dysmenorrhea: A systematic review and meta-analysis. Int. J. Environ. Res. Public. Health, 18.","DOI":"10.3390\/ijerph18157832"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.NPR.0000454984.19413.28","article-title":"Complementary and alternative treatments for primary dysmenorrhea in adolescents","volume":"39","author":"Yu","year":"2014","journal-title":"Nurse Pract."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1093\/ptj\/pzz101","article-title":"Therapeutic exercise in the treatment of primary dysmenorrhea: A systematic review and meta-analysis","volume":"99","year":"2019","journal-title":"Phys. Ther."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"ES205","DOI":"10.36076\/ppj.2012\/15\/ES205","article-title":"Dysfunctional endogenous analgesia during exercise in patients with chronic pain: To exercise or not to exercise?","volume":"15","author":"Nijs","year":"2012","journal-title":"Pain. Physician"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.math.2009.12.006","article-title":"Adverse events and manual therapy: A systematic review","volume":"15","author":"Carnes","year":"2010","journal-title":"Man. Ther."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jbmt.2017.09.025","article-title":"Effects of spinal manipulation and myofascial techniques on heart rate variability: A systematic review","volume":"22","author":"Borges","year":"2018","journal-title":"J. Bodyw. Mov. Ther."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.explore.2017.08.001","article-title":"A systematic review and meta-analysis of the efficacy of manipulative therapy in women with primary dysmenorrhea","volume":"13","author":"Abaraogu","year":"2017","journal-title":"Explore"},{"key":"ref_32","first-page":"165","article-title":"Osteopathic manipulative treatment of primary dysmenorrhea and related factors: A randomized controlled trial","volume":"6","author":"Zecchillo","year":"2017","journal-title":"Int. J. Med. Res. Health Sci."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1111\/pme.12404","article-title":"Changes in pain perception after pelvis manipulation in women with primary dysmenorrhea: A randomized controlled trial","volume":"15","author":"Ricard","year":"2014","journal-title":"Pain. Med."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0167-5273(02)00057-8","article-title":"Functional assessment of heart rate variability: Physiological basis and practical applications","volume":"84","author":"Pumprla","year":"2002","journal-title":"Int. J. Cardiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1097\/01.ajp.0000131413.07468.8e","article-title":"Sacroiliac joint dysfunction: Evaluation and management","volume":"21","author":"Zelle","year":"2005","journal-title":"Clin. J. Pain."},{"key":"ref_36","unstructured":"Lawrence, D.J., Cassidy, J.D., McGregor, M., Meeker, W.C., and Vernon, H.T. (1996). Mechanical, physiologic, and neuromuscular considerations of chiropractic treatments. Advances in Chiropractic, Mosby-Year Book."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.jmpt.2006.01.010","article-title":"The effect of sacroiliac joint manipulation on feed-forward activation times of the deep abdominal musculature","volume":"29","author":"Marshall","year":"2006","journal-title":"J. Manipulative Physiol. Ther."},{"key":"ref_38","first-page":"125","article-title":"A comparative study on heat transfer characteristics in tissue model with application of heating or cooling therapeutic modalities","volume":"30","author":"Kim","year":"2013","journal-title":"J. Acupunct. Res."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/clc.4960130811","article-title":"Heart rate variability","volume":"13","author":"Malik","year":"1990","journal-title":"Clin. Cardiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"493","DOI":"10.14474\/ptrs.2022.11.4.493","article-title":"Effects of High-Frequency Treatment using Radiofrequency on Autonomic Nervous System and Pain in Women with Dysmenorrhea","volume":"11","author":"Park","year":"2022","journal-title":"Phys. Ther. Rehabil. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Munoz, M.L., Van Roon, A., Riese, H., Thio, C., Oostenbroek, E., Westrik, I., de Geus, E.J., Gansevoort, R., Lefrandt, J., and Nolte, I.M. (2015). Validity of (ultra-) short recordings for heart rate variability measurements. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0138921"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"e32","DOI":"10.5301\/heartint.5000232","article-title":"Influence diagram of physiological and environmental factors affecting heart rate variability: An extended literature overview","volume":"11","author":"Fatisson","year":"2016","journal-title":"Heart Int."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1526-4637.2007.00308.x","article-title":"Effectiveness of transcutaneous electrical nerve stimulation and interferential current in primary dysmenorrhea","volume":"8","author":"Tugay","year":"2007","journal-title":"Pain. Med."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.apmr.2011.05.027","article-title":"Sacroiliac joint manipulation attenuates alpha-motoneuron activity in healthy women: A quasi-experimental study","volume":"93","author":"Orakifar","year":"2012","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ijosm.2008.07.003","article-title":"The effects of high-velocity low-amplitude thrust manipulation and mobilisation techniques on pressure pain threshold in the lumbar spine","volume":"12","author":"Thomson","year":"2009","journal-title":"Int. J. Osteopath. Med."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1097\/00006842-196811000-00006","article-title":"The development of a menstrual distress questionnaire","volume":"30","author":"Moos","year":"1968","journal-title":"Psychosom. Med."},{"key":"ref_47","unstructured":"Kim, H., Hong, K., Park, Y., and Kim, J. (1999, January 23\u201327). Cultural comparison of menstrual discomforts and menstrual attitudes between Koreans and Americans. Sexuality in the Millennium. Proceedings of the 14th World Congress of Sexology, Hong Kong, China."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.jmpt.2018.12.005","article-title":"Autonomic effects of spinal manipulative therapy: Systematic review of randomized controlled trials","volume":"42","author":"Araujo","year":"2019","journal-title":"J. Manipulative Physiol. Ther."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12998-019-0235-1","article-title":"The acute effects of joint manipulative techniques on markers of autonomic nervous system activity: A systematic review and meta-analysis of randomized sham-controlled trials","volume":"27","author":"Picchiottino","year":"2019","journal-title":"Chiropr. Man. Therap."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.jcm.2008.04.001","article-title":"Sympathetic and parasympathetic responses to specific diversified adjustments to chiropractic vertebral subluxations of the cervical and thoracic spine","volume":"7","author":"Welch","year":"2008","journal-title":"J. Chiropr. Med."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.jmpt.2006.08.011","article-title":"The effects of thoracic manipulation on heart rate variability: A controlled crossover trial","volume":"29","author":"Budgell","year":"2006","journal-title":"J. Manipulative Physiol. Ther."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jmpt.2006.03.010","article-title":"Effect of chiropractic care on heart rate variability and pain in a multisite clinical study","volume":"29","author":"Zhang","year":"2006","journal-title":"J. Manipulative Physiol. Ther."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.mehy.2015.10.003","article-title":"Measureable changes in the neuro-endocrinal mechanism following spinal manipulation","volume":"85","author":"Sampath","year":"2015","journal-title":"Med. Hypotheses"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"3704964","DOI":"10.1155\/2016\/3704964","article-title":"Manipulation of dysfunctional spinal joints affects sensorimotor integration in the prefrontal cortex: A brain source localization study","volume":"2016","author":"Lelic","year":"2016","journal-title":"Neural Plast."},{"key":"ref_55","first-page":"12","article-title":"Cerebral metabolic changes in men after chiropractic spinal manipulation for neck pain","volume":"17","author":"Ogura","year":"2011","journal-title":"Altern. Ther. Health Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"340","DOI":"10.2519\/jospt.2013.4631","article-title":"Using functional magnetic resonance imaging to determine if cerebral hemodynamic responses to pain change following thoracic spine thrust manipulation in healthy individuals","volume":"43","author":"Sparks","year":"2013","journal-title":"J. Orthop. Sports Phys. Ther."},{"key":"ref_57","unstructured":"Chila, A.G. (2011). Pelvis and sacrum. Foundations of Osteopathic Medicine, Lippincott Williams & Wilkins."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/01.brs.0000147800.88242.48","article-title":"Effect of spinal manipulation duration on low threshold mechanoreceptors in lumbar paraspinal muscles: A preliminary report","volume":"30","author":"Sung","year":"2005","journal-title":"Spine"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.clinbiomech.2015.01.005","article-title":"Sensorimotor function of the cervical spine in healthy volunteers","volume":"30","author":"Artz","year":"2015","journal-title":"Clin. Biomech."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jmpt.2008.02.005","article-title":"Prospective case series on the effects of lumbosacral manipulation on dysmenorrhea","volume":"31","author":"Holtzman","year":"2008","journal-title":"J. Manipulative Physiol. Ther."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/S0161-4754(99)70018-7","article-title":"A randomized, placebo-controlled clinical trial on the efficacy of chiropractic therapy on premenstrual syndrome","volume":"22","author":"Walsh","year":"1999","journal-title":"J. Manipulative Physiol. Ther."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3233\/BMR-140472","article-title":"The role of the descending inhibitory pain mechanism in musculoskeletal pain following high-velocity, low amplitude thrust manipulation. A review of the literature","volume":"27","author":"Savva","year":"2014","journal-title":"J. Back. Musculoskelet. Rehabil."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13643-015-0162-8","article-title":"Descending pain modulation in irritable bowel syndrome (IBS): A systematic review and meta-analysis","volume":"4","author":"Chakiath","year":"2015","journal-title":"Syst. Rev."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/BF02292765","article-title":"Pain-autonomic interactions: A selective review","volume":"11","author":"Benarroch","year":"2001","journal-title":"Clin. Auton. Res."},{"key":"ref_65","first-page":"CD001896","article-title":"Surgical interruption of pelvic nerve pathways for primary and secondary dysmenorrhoea","volume":"4","author":"Proctor","year":"2005","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1197\/S1069-6563(03)00372-5","article-title":"Clinically important change in the visual analog scale after adequate pain control","volume":"10","author":"Lee","year":"2003","journal-title":"Acad. Emerg. Med."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.16965\/ijpr.2019.154","article-title":"Effect Of Lumbar Spine Manipulation On Menstrual Distress","volume":"8","author":"Gurav","year":"2020","journal-title":"Int. J. Physiother. Res."},{"key":"ref_68","first-page":"147","article-title":"Pain pressure threshold in the region of the sacroiliac joint in patients diagnosed with sacroiliac joint pain","volume":"19","author":"Szadek","year":"2016","journal-title":"Pain. Physician"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1542-474X.2008.00213.x","article-title":"Effects of cigarette smoking on heart rate variability and plasma N-terminal pro-B-type natriuretic peptide in healthy subjects: Is there the relationship between both markers?","volume":"13","author":"Alyan","year":"2008","journal-title":"Ann. Noninvasive Electrocardiol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00421-008-0800-0","article-title":"Effect of physical activity on heart rate variability in normal weight, overweight and obese subjects: Results from the SAPALDIA study","volume":"104","author":"Schindler","year":"2008","journal-title":"Eur. J. Appl. Physiol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1161\/CIRCULATIONAHA.113.005361","article-title":"Physical activity and heart rate variability in older adults: The Cardiovascular Health Study","volume":"129","author":"Sattelmair","year":"2014","journal-title":"Circulation"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.1097\/00007632-199611150-00009","article-title":"The value of medical history and physical examination in diagnosing sacroiliac joint pain","volume":"21","author":"Dreyfuss","year":"1996","journal-title":"Spine"},{"key":"ref_73","first-page":"1459","article-title":"Sacroiliac sprain: An overlooked cause of back pain","volume":"46","author":"LeBlanc","year":"1992","journal-title":"Am. Fam. Physician"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/12\/2068\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:52:58Z","timestamp":1760115178000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/60\/12\/2068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,16]]},"references-count":73,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["medicina60122068"],"URL":"https:\/\/doi.org\/10.3390\/medicina60122068","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,16]]}}}