{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T13:32:04Z","timestamp":1782567124224,"version":"3.54.5"},"reference-count":27,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: To assess pregnancy and delivery complications in obese women with gestational diabetes mellitus (GDM) and neonatal weight and condition after birth. Materials and Methods: A retrospective tertiary referral centre study included all cases of GDM in the Department of Obstetrics and Gynaecology of the Lithuanian University of Health Sciences (LUHS) Birth Registry from 1 January 2019 to 31 December 2019. We included 583 women with GDM and singleton pregnancies. Women were divided into two groups according to their pre-pregnancy weight: 202 were obese (BMI \u2265 30 kg\/m2), and 381 were weight (BMI 18.5\u201324.9 kg\/m2). Survey data were analysed using IBM SPSS Statistics 26.0 and MS Excel 2016 software. A value of p &lt; 0.05 was considered significant. Results: Fasting glycaemia was significantly higher in obese women with GDM than in normal-weight women with GDM (p &lt; 0.001). In addition, fasting glycaemia was higher in obese women with GDM requiring insulin correction than in normal-weight women (p = 0.006). OGTT 0-min glycaemia was higher in obese than in non-obese women with gestational diabetes (p &lt; 0.001). Women with pre-pregnancy obesity had a higher incidence of primary hypertension (p &lt; 0.001), hypertensive disorders in pregnancy (p &lt; 0.001), gestational cholestasis (p = 0.002), polyhydramnios (p &lt; 0.001), induced labour (p &lt; 0.001), and caesarean section (p = 0.015), with emergency caesarean sections being more frequent than planned caesarean sections (p = 0.011) compared to normal-weight women with GDM. Labour dystocia (p = 0.003) and foetal distress (p = 0,019) were more common during labour in obese women. Neonates of these women more often had macrosomia (p &lt; 0.001) and lower Apgar scores at 1 min (p = 0.024) and at 5 min (p = 0.024) compared to neonates of normal-weight women. Conclusions: Obese women with GDM experience more pregnancy complications than normal-weight women with GDM.<\/jats:p>","DOI":"10.3390\/medicina61010051","type":"journal-article","created":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T11:24:19Z","timestamp":1735730659000},"page":"51","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pregnancy Complications and Outcomes in Obese Women with Gestational Diabetes"],"prefix":"10.3390","volume":"61","author":[{"given":"Gitana","family":"Ramonien\u0117","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Medical Academy, Lithuanian University of Health Sciences, A. Mickevicius St. 7, 44307 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8011-0765","authenticated-orcid":false,"given":"Laura","family":"Malakauskien\u0117","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Medical Academy, Lithuanian University of Health Sciences, A. Mickevicius St. 7, 44307 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5384-0738","authenticated-orcid":false,"given":"Egl\u0117","family":"Savukyn\u0117","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Medical Academy, Lithuanian University of Health Sciences, A. Mickevicius St. 7, 44307 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laima","family":"Maleckien\u0117","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Medical Academy, Lithuanian University of Health Sciences, A. Mickevicius St. 7, 44307 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Gruzdait\u0117","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Medical Academy, Lithuanian University of Health Sciences, A. Mickevicius St. 7, 44307 Kaunas, Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,1]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2020, November 16). Diagnostic Criteria and Classification of Hyperglycemia First Detected in Pregnancy. 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