{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:49:04Z","timestamp":1785426544022,"version":"3.56.0"},"reference-count":44,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Sleep and pain are non-motor symptoms encountered frequently in Parkinson\u2019s disease (PD). Several subtypes of pain have been identified in PD, with different associations with other non-motor symptoms. To evaluate the prevalence of various subtypes of pain in a PD cohort and their associations with sleep disturbances and quality of sleep. Materials and Methods: In this study, 131 consecutive PD patients were assessed, focusing on pain and sleep using several validated scales and questionnaires. Results: According to KPPQ, the most reported types of pain were musculoskeletal pain (82.44%), nocturnal pain (58.77%), and radicular pain (55.72%). \u201cBad sleepers\u201d (PSQI score &gt; 5) reported significantly more pain than \u201cgood sleepers\u201d regarding all KPPS subdomains, with statistically significant differences observed in the following domains: musculoskeletal pain (5.48 \u00b1 3.50 vs. 2.70 \u00b1 2.67, p &lt; 0.001), chronic pain, specifically central pain (1.19 \u00b1 2.01 vs. 0.15 \u00b1 0.71, p = 0.004), nocturnal pain, specifically pain related to akinesia (2.26 \u00b1 2.74 vs. 0.64 \u00b1 1.22, p = 0.001), and radicular pain (4.35 \u00b1 4.20 vs. 2.45 \u00b1 3.55, p = 0.022). The prevalence of sleep disturbances was higher in patients with nocturnal pain (odds = 1.165, 95% CI: 1.064\u20131.276, p = 0.001), orofacial pain (odds = 1.108, 95% CI: 1.051\u20131.167, p &lt; 0.001), and radicular pain (odds = 1.015, 95% CI: 1.015\u20131.149, p = 0.015). Conclusions: Pain is common in PD patients with sleep disorders. Identifying specific types of pain that are associated with sleep disorders and their correct management may improve sleep quality.<\/jats:p>","DOI":"10.3390\/medicina61040591","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T04:17:14Z","timestamp":1742962634000},"page":"591","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Sleep Disturbances and Pain Subtypes in Parkinson\u2019s Disease"],"prefix":"10.3390","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0251-4043","authenticated-orcid":false,"given":"Stefania","family":"Diaconu","sequence":"first","affiliation":[{"name":"Department of Neurology, County Clinic Hospital, 500326 Brasov, Romania"},{"name":"Faculty of Medicine, Transilvania University, 500019 Brasov, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Ciopleias","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Transilvania University, 500019 Brasov, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Zarnoveanu","sequence":"additional","affiliation":[{"name":"Department of Neurology, County Clinic Hospital, 500326 Brasov, Romania"},{"name":"Faculty of Medicine, Transilvania University, 500019 Brasov, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7394-7161","authenticated-orcid":false,"given":"Cristian","family":"Falup-Pecurariu","sequence":"additional","affiliation":[{"name":"Department of Neurology, County Clinic Hospital, 500326 Brasov, Romania"},{"name":"Faculty of Medicine, Transilvania University, 500019 Brasov, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.sleep.2021.02.036","article-title":"Sleep problems affect quality of life in Parkinson\u2019s disease along disease progression","volume":"81","author":"Liguori","year":"2021","journal-title":"Sleep Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jocn.2019.08.058","article-title":"Potential predictors of quality of life in Parkinson\u2019s Disease: Sleep and mood disorders","volume":"70","author":"Palmeri","year":"2019","journal-title":"J. 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